Genomic Location: chr6:8605039...8606371
NR annotation: XP_031561667.1, tissue inhibitor of metalloproteinase-like [Actinia tenebrosa]
Species Condylactis gigantea · all data for this species · gene families
| CDS |
| ENSKFPT00000033941 |
| Transcript |
| ENSKFPT00000033941 |
| Protein |
| ENSKFPP00000031386.1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000896 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00965 all species → | TIMP | Tissue inhibitor of metalloproteinase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001820 all species → | Family | Protease inhibitor I35 (TIMP) | Interproscan |
| IPR008993 all species → | Homologous_superfamily | Tissue inhibitor of metalloproteinases-like, OB-fold | Interproscan |
| IPR027465 all species → | Homologous_superfamily | Proteinase inhibitor I35b (TIMP), C-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11844 all species → | METALLOPROTEASE INHIBITOR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0002020 all species → | Molecular Function | protease binding | Interproscan |
| GO:0005615 all species → | Cellular Component | extracellular space | Interproscan |
| GO:0008191 all species → | Molecular Function | metalloendopeptidase inhibitor activity | Interproscan |
| GO:0010033 all species → | Biological Process | obsolete response to organic substance | Interproscan |
| GO:0010951 all species → | Biological Process | negative regulation of endopeptidase activity | Interproscan |
| GO:0031012 all species → | Cellular Component | extracellular matrix | Interproscan |
| GO:0051045 all species → | Biological Process | negative regulation of membrane protein ectodomain proteolysis | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K16866 | TIMP3; metalloproteinase inhibitor 3 | - | Peptidases and inhibitors | ko01002 | deepkoala |
Genes whose expression across the transcriptome samples of Condylactis gigantea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Condylactis gigantea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
