Gene detail

Detailed information of ENSKFPP00000033729.1 in Condylactis gigantea

Genomic Location: chr8:4479847...4489693
NR annotation: XP_028515858.1, sodium/potassium-transporting ATPase subunit alpha-2 [Exaiptasia diaphana]
Species Condylactis gigantea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSKFPT00000036565

ATGGCAGAAACTGCAGAGCTAGCACTCAATGATATTGAAGTGAAGGAAGATGGTGAAAATGAAGCAGAAGGAGAGGCGTCACCCGATCCCAGCCCTACGGAGGATACTCAAGTGGAAGAAAACGTGACGCAGGAAAATGTTGAAGCTGAGCCAGGACCTACAGAAGGGAAGGGAACAGAAGTGGCTAACAAACTGGATAAACCGGGCCCTTCAGAGGTAGGGCAGGGGGTGGTTACCAAACCAAAACAACCAACCATGAAGAAAGCAGAAAAGGGCAAAAAGAACTTGGATGATCTGAAGCAGGAACTGGAAATGGTGAGATATCTTGGGCTTACACAGGCGGAAGCAGAGAAGCGACTACAACGTGATGGTCCAAACTGTCTGACCCCACCCCCTACAGTTCCAGAATGGGTCAAATTTTGCAGACTCTTATTTGGAGGTTTCTCGATGCTATTGTGGACAGGCGCGATCCTTTGTTTCGCAATCTATGGAATCAAAGTTGCGACTGAAGAAGAGCCTTCACAGGATGACTTATACCTTGGAGTCGTGTTGGCCACTGTCGTGGTGATAACGGGATGCTTCTCGTACTATCAGGAAGCAAAAAGCTCAAAGATCATGGAAAGCTTCAAGAACATGGTTCCTCTGGAAGCTACTATTCTTCGTGATGGTGTTAAAGTCAAGAAGAATTCAGAGGAGGTGGTTGTTGGAGACATCATCTTTGTTGCGTTTGGTGACCGAATTCCAGCAGATATCAGGGTGTTGGAATCAAAAGGATTCAAGGTTGATAACTCATCGTTGACTGGCGAATCTGAGCCTCAAGCACGCAGCCCAGACTGCACCAATCCGAACCCACTGGAGACTAAAAACCTGGCATTCTTCTCAACCAACGCAGTAGAAGGCACTTGCATCGGTCTGGTCATCCAAACGGGAGATTCCACTGTTATGGGACGTATTGCTAACCTGGCTAGTGGTCTCGATACTGGCAAGACACCCATCGCTATCGAGATTTCTCATTTCATCCACATTGTCACTGGAGTAGCTGTTTCTCTGGGTGTttcattcttcatcatttcttTTGTGCTGAATTACACGTTTCTTCAAGCTGTCATGTTCTTGATTGGCATCATTGTGGCTAATGTTCCAGAGGGTCTTTTAGCTACTGTCACGGTATGCTTGACCCTGACTGCTAAACGCATGGCCTCCAAGAACTGCTTGGTGAAGAATCTTGAAGCTGTGGAAACTCTTGGAAGTACATCTACCATCTGTTCCGATAAAACTGGTACACTCACCCAGAACAGGATGACTGTCGCTCATATGTGGTTTGATAACAAGATCGTGGAGGCAGACACGACAGAAGATCAAAGTGGAGTTACAATGGATAAGTCCGACACTTGGAATGCTCTGTGTCATATCGCAGGGCTATGTAACCGAGCAGAATTCGTTGTTGAAGCCGAAGACAAACCAGTTTTAAAACGTGATACCATGGGCGGCAATGCATCAGAGGCGGCTCTCCTCAAGTGTGTTGAACTCCAAGTTGGCAGCGTTAGTCTGATGAGAGAAAAGAACCCAATGGTGGCAGAGATTCCTTTCAATTCCACCAGCAAATACCACATAAGCATCCACGAGATTCAAGACTCGAAGGAAAACAGTCACATCTTGCTGATTAAGGGCGCTCCTGAGCGCGTCCTTGATCGTTGCAGTACCATTCTTTTAGATGGGAAGGAACAGCCTCTAAACGTCGACATGAAAGAAGCCTTTGAACAGGCTTACTTGAATCTTGGCGGCCTGGGTGAACGTGTACTTGGCTTTGGACATTATTTCCTATCCAAGGACAGCTTCCCCAAGGGATTTGAGTTTACGACAGATGACCCTGTTAATTTCCCATTGGAGAACCTCTGTTTTGTTGGTCTCATGTCCATGATCGACCCCCCAAGAGCTGCTGTGCCTGATGCTGTCAGCAAATGTCGTGGTGCTGGCATCAAAGTCATCATGGTTACTGGAGACCATCCTATCACTGCCAAGGCTATTGCCCGTGGTGTCGGCATCATCTCTGAAGGTACTGAGACCGTCGAGGACATTTCAATCCGCCTTAATATTCCTATCGAAGAGGTTAACCCAAGAGATGCTAAGGCAGTTGTTGTGCATGGTGGAGAACTCAAGAACATGGATCAAGAGTACCTAGACGACATTCTTCGAGAGCACACAGAGATCGTGTTTGCTCGTACTTCTCCTCAGCAAAAGCTGATCATTGTTGAGGGTTGCCAGAGAATGGGTGCTATTGTCGCTGTGACTGGCGATGGTGTCAATGATTCCCCTGCCTTGAAAAGAGCTGACATTGgtGTTGCCATGGGAATAGCTGGTTCAGATGTGTCTAAACAAGCTGCCGACATGATTCTGCTGGATGACAATTTTGCTTCCATCGTCACTGGAGTTGAAGAAGGTCGTTTGATCTTTGATAACTTGAAGAAGTCCATTGCCTACACACTGACCAGTAACATCCCTGAGATCACACCATTCTTGATGTTCATCGTGATTGGCATTCCTCAGCCACTCGGGGTGGTTACCATCCTATGCATTGATCTTGGCACTGATATGGTCCCTGCCATCTCCCTTGCCTATGAAGAAGCTGAAAGTGACATCATGAAACGAAAACCGAGAGATGCTAAGAAGGACAAACTTGTCAATGAAAGGTTGATTGCAATGACGTATGGACAGATTGGCTTTATTCAGGCTCTGGGTGGCTTCTTCACATACTTCGTGATCATGGGTGAGAATGGCTTCTATCCTTCGAGACTGATAGGAATCCGCTCTGAATGGGAAGACAAGAACAATCATGCAGTCCTGGATAGCTATGACCAAGAATGGAGTTACCGTCAGAGGAAGGTTCTGGAATACACCTGCCATACGGCATTCTTCATCAGCATTGTGGTGGTGCAGTGGGCTGATTTGATCATCTGCAAGACTAGAAAAAACTCCATCCTCACCCAAAAGATGACCAACAACGTACTGAACTTTGCCTTGGTATTCGAGACACTGTTGGCAGCCACGCTCTCATACACCCCTGGCCTATCTCACGGCTTAAATATGTACCCACTTAATGCATTGTGGTGGTTTCCAGCCATACCTTTCAGTTTACTGATCTTCGTGTATGATGAGGTCCGTCGATACTTTATTCGTAAATGGCCTGGATGCTGGCTTGAGCAGGAGACCTACTATTAG

Transcript

ENSKFPT00000036565

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P24798	Sodium/potassium-transporting ATPase subunit alpha-3 OS=Gallus gallus OX=9031 GN=ATP1A3 PE=2 SV=1
P13637	Sodium/potassium-transporting ATPase subunit alpha-3 OS=Homo sapiens OX=9606 GN=ATP1A3 PE=1 SV=3
Q6PIC6	Sodium/potassium-transporting ATPase subunit alpha-3 OS=Mus musculus OX=10090 GN=Atp1a3 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001595 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00702 all species →	Hydrolase	haloacid dehalogenase-like hydrolase	Domain	Interproscan
PF00689 all species →	Cation_ATPase_C	Cation transporting ATPase, C-terminus	Family	Interproscan
PF00690 all species →	Cation_ATPase_N	Cation transporter/ATPase, N-terminus	Domain	Interproscan
PF00122 all species →	E1-E2_ATPase	E1-E2 ATPase	Family	Interproscan
PF13246 all species →	Cation_ATPase	Cation transport ATPase (P-type)	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR008250 all species →	Homologous_superfamily	P-type ATPase, A domain superfamily	Interproscan
IPR001757 all species →	Family	P-type ATPase	Interproscan
IPR006068 all species →	Domain	Cation-transporting P-type ATPase, C-terminal	Interproscan
IPR004014 all species →	Domain	Cation-transporting P-type ATPase, N-terminal	Interproscan
IPR023299 all species →	Homologous_superfamily	P-type ATPase, cytoplasmic domain N	Interproscan
IPR018303 all species →	PTM	P-type ATPase, phosphorylation site	Interproscan
IPR023214 all species →	Homologous_superfamily	HAD superfamily	Interproscan
IPR050510 all species →	Family	Cation transport ATPase (P-type)	Interproscan
IPR036412 all species →	Homologous_superfamily	HAD-like superfamily	Interproscan
IPR005775 all species →	Family	P-type ATPase subfamily IIC, subunit alpha	Interproscan
IPR044492 all species →	Domain	P-type ATPase, haloacid dehalogenase domain	Interproscan
IPR023298 all species →	Homologous_superfamily	P-type ATPase, transmembrane domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43294 all species →	SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005215 all species →	Molecular Function	transporter activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0016887 all species →	Molecular Function	ATP hydrolysis activity	Interproscan
GO:0000166 all species →	Molecular Function	nucleotide binding	Interproscan
GO:0005391 all species →	Molecular Function	P-type sodium:potassium-exchanging transporter activity	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006883 all species →	Biological Process	intracellular sodium ion homeostasis	Interproscan
GO:0019829 all species →	Molecular Function	ATPase-coupled monoatomic cation transmembrane transporter activity	Interproscan
GO:0030007 all species →	Biological Process	intracellular potassium ion homeostasis	Interproscan
GO:0036376 all species →	Biological Process	sodium ion export across plasma membrane	Interproscan
GO:1902600 all species →	Biological Process	proton transmembrane transport	Interproscan
GO:1990573 all species →	Biological Process	potassium ion import across plasma membrane	Interproscan
GO:0006813 all species →	Biological Process	potassium ion transport	Interproscan
GO:0008556 all species →	Molecular Function	P-type potassium transmembrane transporter activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01539	ATP1A; sodium/potassium-transporting ATPase subunit alpha	EC:7.2.2.13	Exosome	ko04147	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Condylactis gigantea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Condylactis gigantea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →