Detailed information of ENSKFPP00000035136.1 in Condylactis gigantea

Genomic Location: chr8:1634199...1668249
NR annotation: XP_031569233.1, LOW QUALITY PROTEIN: dynein heavy chain 8, axonemal-like [Actinia tenebrosa]
Species Condylactis gigantea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q91XQ0Dynein axonemal heavy chain 8 OS=Mus musculus OX=10090 GN=Dnah8 PE=1 SV=2
Q8TE73Dynein axonemal heavy chain 5 OS=Homo sapiens OX=9606 GN=DNAH5 PE=1 SV=3
Q96JB1Dynein axonemal heavy chain 8 OS=Homo sapiens OX=9606 GN=DNAH8 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0000599 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF08393
all species →
DHC_N2Dynein heavy chain, N-terminal region 2FamilyInterproscan
PF03028
all species →
Dynein_heavyDynein heavy chain region D6 P-loop domain DomainInterproscan
PF12780
all species →
AAA_8P-loop containing dynein motor region D4DomainInterproscan
PF17857
all species →
AAA_lid_1AAA+ lid domainDomainInterproscan
PF08385
all species →
DHC_N1Dynein heavy chain, N-terminal region 1FamilyInterproscan
PF12781
all species →
AAA_9ATP-binding dynein motor regionDomainInterproscan
PF18198
all species →
AAA_lid_11Dynein heavy chain AAA lid domainDomainInterproscan
PF12777
all species →
MTMicrotubule-binding stalk of dynein motorDomainInterproscan
PF12774
all species →
AAA_6Hydrolytic ATP binding site of dynein motor regionDomainInterproscan
PF17852
all species →
Dynein_AAA_lidDynein heavy chain AAA lid domainDomainInterproscan
PF18199
all species →
Dynein_CDynein heavy chain C-terminal domainDomainInterproscan
PF12775
all species →
AAA_7P-loop containing dynein motor regionDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR027417
all species →
Homologous_superfamilyP-loop containing nucleoside triphosphate hydrolaseInterproscan
IPR043157
all species →
Homologous_superfamilyDynein heavy chain, AAA1 domain, small subdomainInterproscan
IPR013602
all species →
DomainDynein heavy chain, linkerInterproscan
IPR004273
all species →
DomainDynein heavy chain region D6 P-loop domainInterproscan
IPR024317
all species →
DomainDynein heavy chain, AAA module D4Interproscan
IPR041589
all species →
DomainDynein heavy chain 3, AAA+ lid domainInterproscan
IPR026983
all species →
FamilyDynein heavy chainInterproscan
IPR013594
all species →
DomainDynein heavy chain, tailInterproscan
IPR035706
all species →
DomainDynein heavy chain, ATP-binding dynein motor regionInterproscan
IPR041658
all species →
DomainDynein heavy chain AAA lid domainInterproscan
IPR024743
all species →
DomainDynein heavy chain, coiled coil stalkInterproscan
IPR035699
all species →
DomainDynein heavy chain, hydrolytic ATP-binding dynein motor regionInterproscan
IPR041466
all species →
DomainDynein heavy chain, AAA 5 extension domainInterproscan
IPR042222
all species →
Homologous_superfamilyDynein heavy chain, domain 2, N-terminalInterproscan
IPR041228
all species →
DomainDynein heavy chain, C-terminal domainInterproscan
IPR043160
all species →
Homologous_superfamilyDynein heavy chain, C-terminal domain, barrel regionInterproscan
IPR003593
all species →
DomainAAA+ ATPase domainInterproscan
IPR042219
all species →
Homologous_superfamilyDynein heavy chain AAA lid domain superfamilyInterproscan
IPR042228
all species →
Homologous_superfamilyDynein heavy chain, linker, subdomain 3Interproscan

 PANTHER
PANTHER termDescriptionSource
PTHR46532
all species →
MALE FERTILITY FACTOR KL5Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0007018
all species →
Biological Processmicrotubule-based movementInterproscan
GO:0008569
all species →
Molecular Functionminus-end-directed microtubule motor activityInterproscan
GO:0030286
all species →
Cellular Componentdynein complexInterproscan
GO:0005858
all species →
Cellular Componentaxonemal dynein complexInterproscan
GO:0045505
all species →
Molecular Functiondynein intermediate chain bindingInterproscan
GO:0051959
all species →
Molecular Functiondynein light intermediate chain bindingInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0016887
all species →
Molecular FunctionATP hydrolysis activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K10408DNAH; dynein axonemal heavy chain-Cytoskeleton proteinsko04812deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Condylactis gigantea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Condylactis gigantea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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