Genomic Location: chr9:1104164...1108059
NR annotation: XP_031551578.1, hydroxymethylglutaryl-CoA synthase 1-like [Actinia tenebrosa]
Species Condylactis gigantea · all data for this species · gene families
| CDS |
| ENSKFPT00000038149 |
| Transcript |
| ENSKFPT00000038149 |
| Protein |
| ENSKFPP00000035190.1 |
| UniProt accession | Description |
|---|---|
| P23228 | Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Gallus gallus OX=9031 GN=HMGCS1 PE=1 SV=1 |
| P54961 | Hydroxymethylglutaryl-CoA synthase 1 OS=Blattella germanica OX=6973 GN=HMGCS-1 PE=2 SV=1 |
| P17425 | Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Rattus norvegicus OX=10116 GN=Hmgcs1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005496 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08540 all species → | HMG_CoA_synt_C | Hydroxymethylglutaryl-coenzyme A synthase C terminal | Domain | Interproscan |
| PF01154 all species → | HMG_CoA_synt_N | Hydroxymethylglutaryl-coenzyme A synthase N terminal | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013746 all species → | Domain | Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain | Interproscan |
| IPR016039 all species → | Homologous_superfamily | Thiolase-like | Interproscan |
| IPR013528 all species → | Domain | Hydroxymethylglutaryl-coenzyme A synthase, N-terminal | Interproscan |
| IPR010122 all species → | Family | Hydroxymethylglutaryl-CoA synthase, eukaryotic | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43323 all species → | 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004421 all species → | Molecular Function | hydroxymethylglutaryl-CoA synthase activity | Interproscan |
| GO:0006084 all species → | Biological Process | acetyl-CoA metabolic process | Interproscan |
| GO:0010142 all species → | Biological Process | farnesyl diphosphate biosynthetic process, mevalonate pathway | Interproscan |
| GO:0016746 all species → | Molecular Function | acyltransferase activity | Interproscan |
| GO:0008299 all species → | Biological Process | isoprenoid biosynthetic process | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01641 | HMGCS; hydroxymethylglutaryl-CoA synthase | EC:2.3.3.10 | PPAR signaling pathway | ko03320 | deepkoala |
Genes whose expression across the transcriptome samples of Condylactis gigantea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Condylactis gigantea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
