Genomic Location: chr3:8406880...8415661
NR annotation: XP_029202249.2, nibrin-like [Acropora millepora]
Species Acropora austera · all data for this species · gene families
| CDS |
| ENSKKQT00000027550 |
| Transcript |
| ENSKKQT00000027550 |
| Protein |
| ENSKKQP00000023901.1 |
| UniProt accession | Description |
|---|---|
| O60934 | Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 |
| Q5RCV3 | Nibrin OS=Pongo abelii OX=9601 GN=NBN PE=2 SV=2 |
| Q9JIL9 | Nibrin OS=Rattus norvegicus OX=10116 GN=Nbn PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004927 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08599 all species → | Nbs1_C | DNA damage repair protein Nbs1 | Family | Interproscan |
| PF16508 all species → | NIBRIN_BRCT_II | Second BRCT domain on Nijmegen syndrome breakage protein | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013908 all species → | Domain | Nibrin, C-terminal | Interproscan |
| IPR040227 all species → | Family | Nibrin-related | Interproscan |
| IPR032429 all species → | Domain | Nibrin, second BRCT domain | Interproscan |
| IPR043014 all species → | Homologous_superfamily | Nibrin, second BRCT domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12162 all species → | NIBRIN-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000724 all species → | Biological Process | double-strand break repair via homologous recombination | Interproscan |
| GO:0003684 all species → | Molecular Function | damaged DNA binding | Interproscan |
| GO:0006302 all species → | Biological Process | double-strand break repair | Interproscan |
| GO:0007095 all species → | Biological Process | mitotic G2 DNA damage checkpoint signaling | Interproscan |
| GO:0030870 all species → | Cellular Component | Mre11 complex | Interproscan |
| GO:0032508 all species → | Biological Process | DNA duplex unwinding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10867 | NBN, NBS1; nibrin | - | DNA repair and recombination proteins | ko03400 | deepkoala |
Genes whose expression across the transcriptome samples of Acropora austera tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Acropora austera, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |