Genomic Location: :...
NR annotation: XP_029185427.2, merlin-like [Acropora millepora]
| CDS | |||||
| ENSKKQT00000055653 | |||||
| Transcript |
| ENSKKQT00000055653 |
| Protein |
| ENSKKQP00000047800.1 |
| Uniprot term | Description |
|---|---|
| P35240 | Merlin OS=Homo sapiens OX=9606 GN=NF2 PE=1 SV=1 |
| P59750 | Merlin OS=Papio anubis OX=9555 GN=NF2 PE=3 SV=1 |
| P46662 | Merlin OS=Mus musculus OX=10090 GN=Nf2 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF09379 | FERM_N | FERM N-terminal domain | Domain | Interproscan |
| PF00769 | ERM_C | Ezrin/radixin/moesin family C terminal | Domain | Interproscan |
| PF20492 | ERM_helical | Ezrin/radixin/moesin, alpha-helical domain | Coiled-coil | Interproscan |
| PF00373 | FERM_M | FERM central domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR008954 | Homologous_superfamily | Moesin tail domain superfamily | Interproscan |
| IPR029071 | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR018979 | Domain | FERM, N-terminal | Interproscan |
| IPR019748 | Domain | FERM central domain | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR035963 | Homologous_superfamily | FERM superfamily, second domain | Interproscan |
| IPR014352 | Homologous_superfamily | FERM/acyl-CoA-binding protein superfamily | Interproscan |
| IPR000798 | Family | Ezrin/radixin/moesin-like | Interproscan |
| IPR000299 | Domain | FERM domain | Interproscan |
| IPR011259 | Domain | Ezrin/radixin/moesin, C-terminal | Interproscan |
| IPR011174 | Family | Ezrin/radixin/moesin | Interproscan |
| IPR019749 | Domain | Band 4.1 domain | Interproscan |
| IPR046810 | Domain | Ezrin/radixin/moesin, alpha-helical domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23281 | MERLIN/MOESIN/EZRIN/RADIXIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003779 | Molecular Function | actin binding | Interproscan |
| GO:0008092 | Molecular Function | cytoskeletal protein binding | Interproscan |
| GO:0005856 | Cellular Component | cytoskeleton | Interproscan |
| GO:0005178 | Molecular Function | integrin binding | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0005912 | Cellular Component | adherens junction | Interproscan |
| GO:0008285 | Biological Process | negative regulation of cell population proliferation | Interproscan |
| GO:0008360 | Biological Process | regulation of cell shape | Interproscan |
| GO:0030175 | Cellular Component | filopodium | Interproscan |
| GO:0035330 | Biological Process | regulation of hippo signaling | Interproscan |
| GO:0045177 | Cellular Component | apical part of cell | Interproscan |
| GO:0050839 | Molecular Function | cell adhesion molecule binding | Interproscan |
| GO:1902115 | Biological Process | regulation of organelle assembly | Interproscan |
| GO:1902966 | Biological Process | positive regulation of protein localization to early endosome | Interproscan |
| GO:2000643 | Biological Process | positive regulation of early endosome to late endosome transport | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K16684 | NF2; merlin | - | Cytoskeleton proteins | ko04812 | deepkoala |