Genomic Location: chr10:2512025...2517543
NR annotation: CAB3991681.1, 3-hydroxyanthranilate 3,4-dioxygenase-like [Paramuricea clavata]
Species Eunicella cavolini · all data for this species · gene families
| CDS |
| ENSLDHT00000007285 |
| Protein |
| ENSLDHP00000006872.1 |
| UniProt accession | Description |
|---|---|
| A7RIT9 | 3-hydroxyanthranilate 3,4-dioxygenase OS=Nematostella vectensis OX=45351 GN=v1g178517 PE=3 SV=1 |
| Q0VCA8 | 3-hydroxyanthranilate 3,4-dioxygenase OS=Bos taurus OX=9913 GN=HAAO PE=1 SV=1 |
| P46953 | 3-hydroxyanthranilate 3,4-dioxygenase OS=Rattus norvegicus OX=10116 GN=Haao PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004048 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF06052 all species → | 3-HAO | 3-hydroxyanthranilic acid dioxygenase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR010329 all species → | Family | 3-hydroxyanthranilic acid dioxygenase | Interproscan |
| IPR011051 all species → | Homologous_superfamily | RmlC-like cupin domain superfamily | Interproscan |
| IPR014710 all species → | Homologous_superfamily | RmlC-like jelly roll fold | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR15497 all species → | 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000334 all species → | Molecular Function | 3-hydroxyanthranilate 3,4-dioxygenase activity | Interproscan |
| GO:0005506 all species → | Molecular Function | iron ion binding | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0034354 all species → | Biological Process | 'de novo' NAD biosynthetic process from tryptophan | Interproscan |
| GO:0046874 all species → | Biological Process | quinolinate metabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00452 | HAAO; 3-hydroxyanthranilate 3,4-dioxygenase | EC:1.13.11.6 | Tryptophan metabolism | ko00380 | deepkoala |
Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
