Detailed information of ENSLDHP00000011234.1 in Eunicella cavolini

Genomic Location: chr12:15560598...15563476
NR annotation: XP_028392117.1, DNA-directed RNA polymerase II subunit RPB3-like [Dendronephthya gigantea]
Species Eunicella cavolini · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P97760DNA-directed RNA polymerase II subunit RPB3 OS=Mus musculus OX=10090 GN=Polr2c PE=1 SV=2
Q3T0Q3DNA-directed RNA polymerase II subunit RPB3 OS=Bos taurus OX=9913 GN=POLR2C PE=1 SV=1
P19387DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0007702 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01000
all species →
RNA_pol_A_bacRNA polymerase Rpb3/RpoA insert domainDomainInterproscan
PF01193
all species →
RNA_pol_LRNA polymerase Rpb3/Rpb11 dimerisation domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR036603
all species →
Homologous_superfamilyRNA polymerase, RBP11-like subunitInterproscan
IPR011263
all species →
DomainDNA-directed RNA polymerase, RpoA/D/Rpb3-typeInterproscan
IPR011262
all species →
DomainDNA-directed RNA polymerase, insert domainInterproscan
IPR036643
all species →
Homologous_superfamilyDNA-directed RNA polymerase, insert domain superfamilyInterproscan
IPR022842
all species →
FamilyDNA-directed RNA polymerase subunit Rpo3/Rpb3/RPAC1Interproscan
IPR001514
all species →
Conserved_siteDNA-directed RNA polymerase, 30-40kDa subunit, conserved siteInterproscan
IPR050518
all species →
FamilyArchaeal Rpo3/Eukaryotic RPB3 RNA Polymerase SubunitInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11800
all species →
DNA-DIRECTED RNA POLYMERASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0006351
all species →
Biological ProcessDNA-templated transcriptionInterproscan
GO:0046983
all species →
Molecular Functionprotein dimerization activityInterproscan
GO:0003899
all species →
Molecular FunctionDNA-directed 5'-3' RNA polymerase activityInterproscan
GO:0003677
all species →
Molecular FunctionDNA bindingInterproscan
GO:0001055
all species →
Molecular FunctionRNA polymerase II activityInterproscan
GO:0005665
all species →
Cellular ComponentRNA polymerase II, core complexInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K03011RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3-DNA repair and recombination proteinsko03400deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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