Detailed information of ENSLDHP00000014304.1 in Eunicella cavolini

Genomic Location: chr11:2921020...2931634
NR annotation: XP_028398280.1, methionine aminopeptidase 2B-like [Dendronephthya gigantea]
Species Eunicella cavolini · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P50579Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1
Q3ZC89Methionine aminopeptidase 2 OS=Bos taurus OX=9913 GN=METAP2 PE=2 SV=1
O08663Methionine aminopeptidase 2 OS=Mus musculus OX=10090 GN=Metap2 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0004652 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00557
all species →
Peptidase_M24Metallopeptidase family M24DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR036005
all species →
Homologous_superfamilyCreatinase/aminopeptidase-likeInterproscan
IPR002468
all species →
FamilyPeptidase M24A, methionine aminopeptidase, subfamily 2Interproscan
IPR036388
all species →
Homologous_superfamilyWinged helix-like DNA-binding domain superfamilyInterproscan
IPR036390
all species →
Homologous_superfamilyWinged helix DNA-binding domain superfamilyInterproscan
IPR001714
all species →
FamilyPeptidase M24, methionine aminopeptidaseInterproscan
IPR018349
all species →
Binding_sitePeptidase M24A, methionine aminopeptidase, subfamily 2, binding siteInterproscan
IPR000994
all species →
DomainPeptidase M24Interproscan
IPR050247
all species →
FamilyMethionine Aminopeptidase Type 2Interproscan

 PANTHER
PANTHER termDescriptionSource
PTHR45777
all species →
METHIONINE AMINOPEPTIDASE 2Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0006508
all species →
Biological ProcessproteolysisInterproscan
GO:0070006
all species →
Molecular Functionmetalloaminopeptidase activityInterproscan
GO:0004177
all species →
Molecular Functionaminopeptidase activityInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0008235
all species →
Molecular Functionmetalloexopeptidase activityInterproscan
GO:0035551
all species →
Biological Processobsolete protein initiator methionine removal involved in protein maturationInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01265map; methionyl aminopeptidaseEC:3.4.11.18
Peptidases and inhibitorsko01002deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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