Gene detail

Detailed information of ENSLDHP00000014615.1 in Eunicella cavolini

Genomic Location: chr14:13598727...13603894
NR annotation: CAB4018546.1, argonaute 2 [Paramuricea clavata]
Species Eunicella cavolini · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSLDHT00000015908

ATGAGTGATCAAGGACGCGGGGGAAAGAAAGGCAAAGGACGGGGTAAGAAGCGAGGCAAGGGAAGAGGAgggcaacaacaacagcagcgaCAAAGTGAAAGTGTTCCTGGCGGGTTACAGCAGCCCAGAGATGAACCTCAAGGCGCTGCAGCTTTGCCAGAGCAAAGACAACAGCCACAGCAGGGTCAACAACAatcacagaaacagccacaacAGAAACAACAACCTAGAGATGACCAACAAGGGGGTACAGCATTACCAGAACATAGGCAATCGGCTAAAGGAAAAAGACAACCACAGCAAGGTCAACAACAATCACAGAGACAGCCGCAACAGAAACCGCAACCTGGAGACGACCAACAAGGAGCTACAGCATCGCCAGAACAGAGGCAGCCAGCAAAAGGAAAAGGACAACCACAGCAAGGTCAGCAACAATCAAAGAAACAGCAGCAACAGAAACAGCAACCTACAGACGACCAACAAGGAGCTACAGCATCGCCAGAACAGAGGCAGCCAGCAAAAGGAAAAGGACAACCACAGCAAGGTCAGCAACAATCAAAGAAACAGCAGCAACAGAAACAGCAACCTAAAGATCAAGCAGATGGTGCGGGCCCCAGTAAGCCACAGGGGCAGCCTCCAGCAGCATCGCATGGTGGTCCTAGACCTCAAGGCCCCCCTCAACCCAAAGCTCAGCCGTCAACACAACCACAACCATCTGCAGGAGCAACCAAGCCAGCAACCCCTCAGCAACCCCAATCGCCTCGTGGAGCAGAAAAACCCGACACCCCAGGTCAAAGAAAGGGTAGCCCACCTCGATCAGATAAAGCTGTTCCAAAACCACCTCGACGACCTGATGGTGGAGGCAGATCCGGGCGACCCATCCAACTCCGAGCAAACTTTCTGCCTGTAAGATTGCCAACTAATGACATCCATCACTATGACACAGATATCAAAGAGAAAGGGAAGAAAAGCGGGGAGGGATATACAAAGTCTGAGGCCCCAAAAATTATTCAAGAGGTTGTGAAAATGTACGAGAAGGAAAACCCAAGCGGTCCTAAATTAGCGTATGATAGGACTGGCAAGAACATGTATTGTCGCACTCTGATCCCTGGAATAGGTAAGGACAGTAAGAGATACAACCTGCCGTACACTACAGACAATGGGCGAGAAAAAGAATTTATTGTCGATATTAAATGGACCACTGGTACGGTTAGTCTTTATTATTTAAATGAAGCTCTTGAAGGACGGCATACTGAAATACCATATGATTCCTTGCAAGCAATCGAGGTTGTTCTACAGCAAATGCCAAAAATGAAGTCCATCCAAGTCCGTTCGTCATTTTTTGATTATCCAACCGGCCGCGAGAAAGACCTCGGCGGTGGTGTGCAGGTGTGGAATGGGACATTTGTTAGTATTCGTCCAACTCAGTGGAAGATGATGTTGAATGTTGACACTTGTGCCACTGGTTTTTATAAAGGACAGCCTGTGATAGATTTTATGTGCGATTTCCTTGGTCTCCGAGACTACCCAAGACGCTTGAACGAGACTCAGCGAAGAAAGTTTGGCAAAGAAATAAAATCAATAAAAGTTGAAACAACACATATCAAGAGGAAACAAAAAGCCAGTGGTCTGTCTGTCAAGTCTGCAAAAGATGAAACATTTGATTGTGAAGGTCGAAGAGTTTCAGTGTTGAATTACTTCAAAGATAAGTATAACATCAATTTGCAATATCCAGAGCTGCCCTGCATTCAAATTGGCCAAAAGAAAAACCTCATCCCATTGGAGCTGTGTCGTGTTGTTGATGGCCAAAAGAAGCAGGGGAAGTTGACGGGAGCACAAACGCAACAGATGATTCGTCACACTGCGATACCTGCGCCAGATCGCATGCAAAGAATTATGGAGTTGATACGAAAACTCCACTATGAAAGTGACCCATATTGTCGAGACTTTGGCATCAGTATTGGCAATGAAATGGTATCTATACAAGGACGGGTGTTAGACCCACCACCTATGATGTACGGTCCAAAAAACAGACCAGGAAGAGAGGTGCCTCGTGACGGAGCTTGGAAAATTACAAAGCAAATGCTTGATCCAAAGGAGTTGAGGGAGTGGGCTTTGATATCCTACATGAGTGATGGCCCTAAGAGGAGGGGGGCTGGCAGATATCGTGGCCCAGATTACCTTGATGATCGCGGGATGGACAACCTTATTCACTATCTGGTCGAGGTTGGTCGTGAAAAAGGGGTACATGTTAATGAGAATCCATGCTTTGTTAAAGTAGAAAGAGGTTTTCATGGTACTGACAAACTATTTGGTGATCTCAAGGCTCGTTATCCTAATTTACAGTTAATCGTTGTCGTGTTGCCAGTGGATGGCGATGATTATTATGAGGAAGTCAAGCACTGCGGTGATATTGTCCATGGTATCACAACACAATGTATCAAAGTTGAGCAAGCTTCAAATGATTTCTCTGATTGGAGGAAAAAAGAGACACTTGTTAACCTATGGCTCAAGATCAATGCCAAACTTGGTGGGACAACATGTGCTCTTGACAAGAGTGTAAAGTCTCCAATTTTGCAACGCCCAGTAATCATATTTGGTGCTGATGTCACCCATCCCGGAGCTGGGGACAGAGCTAACCCATCCATTGCAGCAGTGGTAGCAAGCAAAGATACCTACCCAACTCTTTACAATGCAGAAGTTCGTGTGCAGACACACCGTCAGGAAATGATTGCAGATCTTAAAGAAATGGTCAAAACACTGCTCAAGAAATTTCGGGCTTCGACAAGAGCAATTCCTGAAAGGATCATTTTTTACCGCGATGGCGTCAGCGAAGGTCAATTCCGAGATGTCCTGATCAATGAATTATCGGCGATTCAAAGGGCGTGCCTTGAGTTGCAACAGGGGTACACACCTGCTATAACCTTTATTGTTGTCCAGAAGCGTCACCATGCTAGATTCTTTGCAGTGGATCCAAGAGATCGAAAGGGGAAGAGTGGAAATATACCTGCAGGTACGGTGGTTGATCAACAAATCTGTCATCCAACTGAATTCAATTGGTACCTCTGTAGCCATGCTGGTATACAAGGTACCAGCAAACCATCCCTCTACCATGTACTATATGATGACAGCAATTTTGGCTCGGACGACTTACAGATTCTAACCAATCAGTTGTGCTACACGTACGTGCGATGTGCAAGGTCCGTGTCCATCCCTGCCCCTGCCTATTACGCCCACCATGTTGCGTTCCGAGCAAGACATCATTTGAAGATTGAAAGTAGTACCGAAGGCAGTACGGTATCTGATGACTCGGGACCCAAAGAAGTCACCcaagaaatgaaaaatttaGTCAGAGTTCATCCCAACGTGGACTGTACAATGTACTTTGCTTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6QME8	Protein argonaute-2 OS=Bos taurus OX=9913 GN=AGO2 PE=2 SV=1
Q9UKV8	Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3
Q8CJG0	Protein argonaute-2 OS=Mus musculus OX=10090 GN=Ago2 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000826 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02170 all species →	PAZ	PAZ domain	Domain	Interproscan
PF02171 all species →	Piwi	Piwi domain	Family	Interproscan
PF08699 all species →	ArgoL1	Argonaute linker 1 domain	Domain	Interproscan
PF16486 all species →	ArgoN	N-terminal domain of argonaute	Domain	Interproscan
PF16488 all species →	ArgoL2	Argonaute linker 2 domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR003165 all species →	Domain	Piwi domain	Interproscan
IPR036397 all species →	Homologous_superfamily	Ribonuclease H superfamily	Interproscan
IPR003100 all species →	Domain	PAZ domain	Interproscan
IPR014811 all species →	Domain	Argonaute, linker 1 domain	Interproscan
IPR012337 all species →	Homologous_superfamily	Ribonuclease H-like superfamily	Interproscan
IPR032474 all species →	Domain	Protein argonaute, N-terminal	Interproscan
IPR032472 all species →	Domain	Argonaute linker 2 domain	Interproscan
IPR036085 all species →	Homologous_superfamily	PAZ domain superfamily	Interproscan
IPR045246 all species →	Domain	Argonaute-like, PIWI domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22891 all species →	EUKARYOTIC TRANSLATION INITIATION FACTOR 2C	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003676 all species →	Molecular Function	nucleic acid binding	Interproscan
GO:0003723 all species →	Molecular Function	RNA binding	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0003727 all species →	Molecular Function	single-stranded RNA binding	Interproscan
GO:0004521 all species →	Molecular Function	RNA endonuclease activity	Interproscan
GO:0016246 all species →	Biological Process	regulatory ncRNA-mediated post-transcriptional gene silencing	Interproscan
GO:0035198 all species →	Molecular Function	miRNA binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11593	ELF2C, AGO; eukaryotic translation initiation factor 2C	-	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →