Gene detail

Detailed information of ENSLDHP00000015381.1 in Eunicella cavolini

Genomic Location: chr14:13845051...13867956
NR annotation: XP_028395164.1, regulatory-associated protein of mTOR-like isoform X1 [Dendronephthya gigantea]
Species Eunicella cavolini · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSLDHT00000016715

atctACAACTGttcatttctattttatagAAGCAAATGTGAGTGGATTATGATATGCATTCAGCGAAGAAATGCGAGGTCAGAAAATATGAGATCAGTGTCAAGACGTCAGTCCTGTTATGGCAAGGTTGCCGgttcttgttttaaaatgtctGTAGAGGAGGCAGAACTCGACGAAAGCGGTGGAGAAGAAGACGAAGGGGAGATAATTGACTGGCAGTTGCCACTATGTTTCATGAAAAAACGACATCGCGAGCGTATCGAGGGAGCACTGCCACTTGCTCAAACTTGGCGAATGAAAGAAAGGATGAAAACTGTCTCTGTTGCCTTGGCTTTATGTTTGAATATTGGTATTGACCCTCCAGATGTCGTCAAAACATCCCCGTGTGCTCGTATGGAGTGTTGGATagATCCAATGGTGATGACACCACAAAAAGCCTTAGATGAAATTGGCGGTCGTTTGCAAAAGCAATATGAAAGATGGCAGCCACGGGCAAGATACAAGTTGAGCTTAGATCCAACAGTGGATGAAGTGAAGAAATTATGCATGAGTTTAAGAAGAAATGCAAAGGAGGAGAGAGTTCTTTTTCATTACAATGGCCACGGTGTACCACGTCCCACTGCAAATGGCGAAGTATGGGTTTTTAATAAGagttATACTCAGTATATTCCTTTGTCTGTGTATGACTTACAAACATGGATGGGAAGTCCGTCAATATTTGTATATGACTGCTCCAGTGCAGGTATAATTTTAGAGAATTTTAGCCAGTTTTCAAAGCAACGTGAGAAGGAGTATGAGAGATGCAATGCTCAAGGGACAAGTGCCCCAATGCCATCATTCAAAGATTGTATCCAGATAGCAGCATGTCAACCACATGAACTCCTACCAATGCAGCCTGATTTGCCTGCTGATATCTTCACTGCATGTCTGACCACACCAATTAAGATTGCTCTCAGCTGGTTCTGTCAGCAAAACAGTGGGAAATTAGTTGAAGGAATCAACATTGATCTAATTGAAAAAATTCCTGGCAGACTGAATGATCGACGCACCCCACTGGGAGAACTGAACTGGATATTTACTGCCGTCACTGACACGATTGCTTGGAATGTTTTGCCAAGAGAATTATTTCAAAAGCTTTTCCGTCAAGATTTATTGGTTGCTAGTTTATTCCGTAACTTTCTGCTGGCAGAAAGAATCATGAGGTCGTATAACTGCATGCCAATGTCATCTCCGCAGCTACCACCCACCTACCAACATCCCATGTGGAATGCTTGGGACCTGGCTATAGATACATGTTTATCTCAGCTTCATGATGTCGTTAAGAATGGAAAGACGTTTCAGAATAGTTGTTTCTTCTCCCAACAATTGACGGCATTTCAAGTGTGGTTAGCCATGGGTAGGAAAGAACGAAGTCCACCGGAGCAGCTGCCCATTGTGCTTCAGGTTCTTCTCAGTCAAGTTCATAGACTTCGAGCTTTGGATCTTCTTGGACGATTTTTAGATCTTGGTCCTTGGGCTGTTCATTTAgCTCTTTCTGTTGGTATATTTCCTTACGTTCTTAAACTTTTACAAAGCGCTGCAAGAGAGCTGCGTCCATTACTGGTTTTTATCTGGGCAAAAATTTTAGCTGTAGATAATTCATGTCAAGCAGATTTAGTCAAAGACAATGGCCATCGTTATTTTTTGTCAGTTCTTGCTGATCCTTACATGCCGCCTGAACACAGGACAATGGCTGCTTTCATATTGGCAACAATAGTTAAAGATTACCCTGATGGACAGGAAGCATGTCTGCAAGGCAATCTGATCGCAATATGTCTGGAGCAGCTCAGCGATCCACATCCATTGTTACGTCAGTGGCTAGCCCTGTGTCTTGCGAGGACATGGACGAAGTACAATCGTGCAAAATGGTGTGGTGTTAGAGACTCAGCTCACGAGAAGCTCCAGACTCTGAGCTATGACCCTCTCCCTGAGGTTCGTGCTGCGGCCGTATTTGCTTTGGGTCATTTTGTTGGCAATACAGCGGAGAGAACGGATTTAGCGAACCAAGTTGATTTTGGCGTGTGTATGATGCTGACCAACCTGGCTTATGATGGCAGTCCCATTGTGAGAGAGGAAGTTGTGAGAGCATTATATGGTTTGGTATCGCAATTTGAAAGCAACTTTGGAGTCGTCGCGGTCCAGTTTCTTGAGGAGGAAGATCGCTTACGTGATATGCAACCTCAGCCTGCTATGACGTCAACTGGCTGGATTGTTGTCACGCCTGGTGTACCTGTGCCTCCCAACTTGGCCCACGTCTCTCCGCAAACATCGAAGACAAAGTCACGAATCAAGTCACGTGGTTCCGTCCCAAATCTTACAGCGATACCTGGAACGTCGCCAGTTCTCAGCAGTGGTAGTAGTGGTGGAAGCGTTGGTTCTGATTTGCAACTGAGACGAACGACATCGCATGCTCCATTCACGTCACCACAATCCAATGTTTACTCTTCTGTATGGCGGtattttttttttaaattcaattGTTGCTCCAAACTACCCCCAAACATTCTGACAGAGGCAAAAAAGTTTTCTTTCGATAAAACAATGATTTTTAACGCCCAAAatcatgttttaaaatttgtaaattttgcTCATGCGTACCATTTACATTTTAATAGATCCGGTGCCTTCAATGCCCTACAAGACGTCTCAAATATGGCGGGGGTTAAAACTCCAGAGAGGCCACCCTCCACCACACCATCACAAAAACCAAGTGCCACTGGTCTCGCACACTTCCCTCATTCTTATGCCTTTGGTGCAAAAAGACGAATGTTCGACAAAGGACCGGACGTAAGTAGAATTATGTCAGACGAATCTGAGGAAGAAGGAAGTCATCCTCCTGCCGCTTTTGTTGAAACGAAATTTTGTGATTGGTGTTGTAGTTATTTCGCTCAATCAGTCACCAAGCCCCCTGACGAGCATGACCCGTTTAGTGACGTTCACCTTGAGCGAGAAAACAGATTTACAAGAAACGCTCGAGTCAGATTTGAAGctgaaaaacaacaaaaaggtAGAAACTTTAATCGTCTTGATGATCAGATATTTATCAACAGGAATCCCTCACCGCCTTGTGTACTCCGATTTAACCCCTATGAACCCCATCTTGCTGTTGCCGACAGATCTAGAGTAAATATTTGGAATTTCCAAACTGGAACACGTCTCAATCATTTCGAGAATGGGAATCCAAAGCTAACTCGGATAACAGCCATGGAACTTCTTAATTCTCATGATTTGCCTTTGTTACTCACCGGCTCAAATGATGGTGGTGTCCGTATTTGGAGAAATTATACCCAAGGCGAACCTGAACTGGTCACAGCATGGCAAGCACTCTCGAGCCTGCTGCCGTCAACACGCGGCAATGGGTCAGGTTTAGTTGTGAATTGGGAACAACAGACAGGTTGGCTTATGGCGTCAGGAGATGTAAGACATATCCGTGTCTGGGATACTCAGAGAGAGATAAAACTACAGGATATTCCCACGGGAGCAGAAAGTTGTGTTACCAGTCTTGTGTCCGATTATGTCGGTCGTTCTCTGCTGGTGGTCGGCTGTGGTGATGGTTCTGTTCGACTGTTTGACAGAAGATTACCACCAAACGACAGTCGAGTAATGACCATGCGAGAACACCAGAGCTGGGTTGTCAATGTTGTGCTGGAGAGAAGTACTTCAGAGAGTATCATTTCTGCAAGTGTGGATGGAATGGTGAAATTCTGGGATCCGCGTTTTAGCAAATCTGTCCGTAATTTGGAGACAATGGTTGGTCAGATGACCGCATTTGAAGTCCACAGTTCTGCGAAAGTTATGGCAAGTGGCTCAGCAAATCAAATGGTCAAAGTGATAAAGGTGAAAGAAAAGGACTCAGACTGCATTAGCACGATTCGTCACCATGATGGATTTATGGGTCAAAGAATTGGTCCTGTCAACTCTATGAGTTTTCATCCACACCGGGTACACCTGGCCGTCGGTTGCGCTGACTCGATAATTTCTATTTACTCAACGGAAAAGAAGAGATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8K4Q0	Regulatory-associated protein of mTOR OS=Mus musculus OX=10090 GN=Rptor PE=1 SV=1
Q8N122	Regulatory-associated protein of mTOR OS=Homo sapiens OX=9606 GN=RPTOR PE=1 SV=1
Q55BR7	Protein raptor homolog OS=Dictyostelium discoideum OX=44689 GN=raptor PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003932 (this species only) · gene tree & orthology
Ubiquitin family	E3\|E3 adaptor Cullin RING\|CDC20 · all ubiquitin genes in this species
Ubiquitin family	E3\|E3 adaptor Cullin RING\|DWD · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00400 all species →	WD40	WD domain, G-beta repeat	Repeat	Interproscan
PF14538 all species →	Raptor_N	Raptor N-terminal CASPase like domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR029347 all species →	Domain	Raptor, N-terminal CASPase-like domain	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR015943 all species →	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	Interproscan
IPR001680 all species →	Repeat	WD40 repeat	Interproscan
IPR011989 all species →	Homologous_superfamily	Armadillo-like helical	Interproscan
IPR004083 all species →	Family	Regulatory associated protein of TOR	Interproscan
IPR036322 all species →	Homologous_superfamily	WD40-repeat-containing domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12848 all species →	REGULATORY-ASSOCIATED PROTEIN OF MTOR	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0009267 all species →	Biological Process	cellular response to starvation	Interproscan
GO:0010506 all species →	Biological Process	regulation of autophagy	Interproscan
GO:0030307 all species →	Biological Process	positive regulation of cell growth	Interproscan
GO:0030674 all species →	Molecular Function	protein-macromolecule adaptor activity	Interproscan
GO:0031929 all species →	Biological Process	TOR signaling	Interproscan
GO:0031931 all species →	Cellular Component	TORC1 complex	Interproscan
GO:0038202 all species →	Biological Process	TORC1 signaling	Interproscan
GO:0071230 all species →	Biological Process	cellular response to amino acid stimulus	Interproscan
GO:0071902 all species →	Biological Process	positive regulation of protein serine/threonine kinase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K07204	RAPTOR; regulatory associated protein of mTOR	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →