Genomic Location: chr14:2387729...2392795
NR annotation: CAB4014069.1, E3 ubiquitin- ligase CHIP-like [Paramuricea clavata]
Species Eunicella cavolini · all data for this species · gene families
| CDS |
| ENSLDHT00000018895 |
| Protein |
| ENSLDHP00000017326.1 |
| UniProt accession | Description |
|---|---|
| A6HD62 | E3 ubiquitin-protein ligase CHIP OS=Rattus norvegicus OX=10116 GN=Stub1 PE=1 SV=1 |
| Q9WUD1 | E3 ubiquitin-protein ligase CHIP OS=Mus musculus OX=10090 GN=Stub1 PE=1 SV=1 |
| Q9UNE7 | E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005407 (this species only) · gene tree & orthology |
| Ubiquitin family | E3|E3 activity RING|U-box · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF12895 all species → | ANAPC3 | Anaphase-promoting complex, cyclosome, subunit 3 | Repeat | Interproscan |
| PF04564 all species → | U-box | U-box domain | Domain | Interproscan |
| PF18391 all species → | CHIP_TPR_N | CHIP N-terminal tetratricopeptide repeat domain | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR003613 all species → | Domain | U-box domain | Interproscan |
| IPR019734 all species → | Repeat | Tetratricopeptide repeat | Interproscan |
| IPR045202 all species → | Domain | CHIP , U-box domain | Interproscan |
| IPR011990 all species → | Homologous_superfamily | Tetratricopeptide-like helical domain superfamily | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR041312 all species → | Domain | CHIP, N-terminal tetratricopeptide repeat domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46803 all species → | E3 UBIQUITIN-PROTEIN LIGASE CHIP | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004842 all species → | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0016567 all species → | Biological Process | protein ubiquitination | Interproscan |
| GO:0000209 all species → | Biological Process | protein polyubiquitination | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0006515 all species → | Biological Process | protein quality control for misfolded or incompletely synthesized proteins | Interproscan |
| GO:0043161 all species → | Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0045862 all species → | Biological Process | positive regulation of proteolysis | Interproscan |
| GO:0051087 all species → | Molecular Function | protein-folding chaperone binding | Interproscan |
| GO:0061630 all species → | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| GO:0071218 all species → | Biological Process | cellular response to misfolded protein | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K09561 | STUB1, CHIP; STIP1 homology and U-box containing protein 1 | EC:2.3.2.27 | Ubiquitin system | ko04121 | deepkoala |
Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
