Gene detail

Detailed information of ENSLDHP00000020339.1 in Eunicella cavolini

Genomic Location: chr16:8129665...8136597
NR annotation: CAB4004496.1, insulin receptor substrate 1-B-like [Paramuricea clavata]
Species Eunicella cavolini · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSLDHT00000022277

ATGGTCAGTTTATCTGTGTATATAACTATTGTAAATCCTAACCAAAAGAAACGCTACTTTGTGCTGGGATTCAACAAGGAAACAGGTGACGCACAATTACAGTATTACGAAAACCCCAAAAAGTGCAGTGCTGAAACTCTAGGCCTTCCAAAGAGAGTAATATCATTGCAACAATGTCTTGGCATTGTCAAAAAAGCTGATGAGAAATTTGGAAACATTCTTGCATTGTACTCTAAAGAAGCAATATTCCGACTGAAAGCTGATACAGATGAAATCCTAGAGGGTTGGTTCACAGATCTGAACAAACTACATCAGATGGAGTATAAAAATTTACAGGATTTAAAATATGATATGGTTTGGAAGGTGAAAGTTGTCCCGCGAGGTCTTGGTGGTGTAAAGAATGTCACTGGCTCATACAAACTTTGTCTAAAAGATAACACGTTATATTTTGTCAATCCCGTCTCACAAGATGTCATCATTGAAGAGAGACTCTATCATGTCCGCAAGTTTGGTTATTGGGACAATTGTGTGTTTATGGAATTTGGACGTTCCACAGCCCTGGGGCCTGGAGAAATATGGATGGAGGTTGAGGATCCTTTGATTGCACAGAAAATAGAAGACAGTTTATCAAGATCAGTAAAACCAAAATCAGAAAGACCAGAACGTAAATCAATGGTTGATGACCCCAGGATAACAGTCACAGAAGAACATCAGAACAATAACAATGAGAGTCCTAAGTCAAGACGACGTACTTTTGTTCAATTACTGGGAATAAGAAAGGGGAAAGGTGATGTGCGACCACATTCCAACTCAATGTCCACAACTCCAGGTAGTTCAGCAGAAGAAcaaataatattcaataataaaaaTGGCAGGCTACCACACAAAACTCCAAACACTGGTGAAGATGAAGATTCAGAAGACAGGCATTATCCAAAGATCGCCCCTCCAGTCCCGTCTGTTCCCAGGACGAAATCACAATCATCAGGATCATTTACAGATGACGGTATCATACACAGGAGGAAAGAAACTTTGGACCTCGAGTCAAAATGTGAACATGTAAGAAGTGAGGAAAATAATTATGCCAACCTTGTCAGACCAAGACGACGATCAGAACGCAAGCAAGATATAAATGCCGTTCGAAAAAATTTTGTAGAGCAATACCACCAATACCAAACGTCCTCCTTGCCCAGGCGTACCAGCAGCAGCTCCAGCAGTGATCCAAAATGGCGTCGCAGCCTGGGCAGTTTCGGCGATGACAGTGATAAAGATAGCACTCGGGGGTCTGACAGAGAAGATGGTGAAGCATTCTTACAGCAGAGTTCAGACCAGTATATACAAATGAGCCCTCGGCAACTGCCTAGAGGTAGTGACTCATCGACTGACGAACTTGGGATAAATGATCCTTTGAGTTCTGACCCTAGCGCATATATGCCTCTCAAACCTCCCACAGGTACTCCTGATCTATACGTCCAAATGAGTCGACCTGGAACAAGTCCAGAAAAGTTGCATAATCGTAGTTCAGACTCATACCATTCCCCCGAGGAGGAAGGCGGAGGACAAGACCCAGAAGTAAGTACCTACGTCAACATGAGGCCTGGATCACATCATGTCACGTCATCAACCTCATCTGATGATCATCCGGGAGATGAACGTTTTGATCATTTGAACCGGGGGGAGAATGCTGTCGGTGGTGATCAAGCTAATTATGTTAATATGAGCCCACAATCGAATAAGCTAAAAAAATCTCGTTCTCAAGTACATCGAGGTGCAGACAATGCTTATATAAATGTCGACATCAATCGCAGCAAAAGTGTTGGTAGTAAATCACCACGATTTTGTATCATGTCTGAGCAAAGTTCGTCCCCGACAAACAATGAGAACCAAGACATTCTGAGATGTTATGTAAATGTGAAACCGAAGGATGCAAGCTCAGATCAAGAACCAAATTATGCTAATTTTGTACCTGTAAACTGCAAGGAAAGCACAGAAAAATCTCCTGGGACAAATAAGCGAGAGTTGAATTATGCTTCAGTAGATTTCTCTAATGACAGTCCCCCCCGGGACAGAGGCTCGCCACAGAGATCTAGGAATCGTGACGCTAATTATTCGAAAATTGATTTTGAGAAGTCTAATGTTCTTGCTGATATTTCAATCACACGAGAACGGCAGTGGCATCACGCATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6P4Y6	Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 GN=irs1 PE=2 SV=1
Q9DF49	Insulin receptor substrate 2-A OS=Xenopus laevis OX=8355 GN=irs2-a PE=2 SV=2
Q5RJW5	Insulin receptor substrate 2-B OS=Xenopus laevis OX=8355 GN=irs2-b PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007645 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02174 all species →	IRS	PTB domain (IRS-1 type)	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR039011 all species →	Family	Insulin receptor substrate	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR002404 all species →	Domain	IRS-type PTB domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10614 all species →	INSULIN RECEPTOR SUBSTRATE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005158 all species →	Molecular Function	insulin receptor binding	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0008286 all species →	Biological Process	insulin receptor signaling pathway	Interproscan
GO:0043548 all species →	Molecular Function	phosphatidylinositol 3-kinase binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K08824	CDKL; cyclin-dependent kinase-like	EC:2.7.11.22	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.