Detailed information of ENSLDHP00000022434.1 in Eunicella cavolini

Genomic Location: chr2:28847752...28874715
NR annotation: XP_046862276.1, LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase UHRF1-like [Xenia sp. Carnegie-2017]
Species Eunicella cavolini · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
B6CHA3E3 ubiquitin-protein ligase UHRF1 OS=Xenopus laevis OX=8355 GN=uhrf1 PE=2 SV=1
F6UA42E3 ubiquitin-protein ligase UHRF1 OS=Xenopus tropicalis OX=8364 GN=uhrf1 PE=3 SV=2
A7E320E3 ubiquitin-protein ligase UHRF1 OS=Bos taurus OX=9913 GN=UHRF1 PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001740 (this species only) · gene tree & orthology
Ubiquitin familyE3|E3 activity RING|PHD · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00628
all species →
PHDPHD-fingerDomainInterproscan
PF02182
all species →
SAD_SRASAD/SRA domainDomainInterproscan
PF00097
all species →
zf-C3HC4Zinc finger, C3HC4 type (RING finger)DomainInterproscan
PF12148
all species →
TTDTandem tudor domain within UHRF1DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR017907
all species →
Conserved_siteZinc finger, RING-type, conserved siteInterproscan
IPR045134
all species →
FamilyUHRF1/2-likeInterproscan
IPR003105
all species →
DomainSRA-YDGInterproscan
IPR015947
all species →
Homologous_superfamilyPUA-like superfamilyInterproscan
IPR011011
all species →
Homologous_superfamilyZinc finger, FYVE/PHD-typeInterproscan
IPR036987
all species →
Homologous_superfamilySRA-YDG superfamilyInterproscan
IPR019787
all species →
DomainZinc finger, PHD-fingerInterproscan
IPR018957
all species →
DomainZinc finger, C3HC4 RING-typeInterproscan
IPR013083
all species →
Homologous_superfamilyZinc finger, RING/FYVE/PHD-typeInterproscan
IPR001965
all species →
DomainZinc finger, PHD-typeInterproscan
IPR021991
all species →
DomainUHRF1, tandem tudor domainInterproscan
IPR001841
all species →
DomainZinc finger, RING-typeInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR14140
all species →
E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0010216
all species →
Biological Processobsolete negative regulation of gene expression via chromosomal DNA cytosine methylationInterproscan
GO:0016567
all species →
Biological Processprotein ubiquitinationInterproscan
GO:0061630
all species →
Molecular Functionubiquitin protein ligase activityInterproscan
GO:0046872
all species →
Molecular Functionmetal ion bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K10638UHRF1, NP95; E3 ubiquitin-protein ligase UHRF1EC:2.3.2.27
Chromosome and associated proteinsko03036deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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