Gene detail

Detailed information of ENSLDHP00000030065.1 in Eunicella cavolini

Genomic Location: chr3:51811998...51829959
NR annotation: XP_028411731.1, diacylglycerol kinase beta-like isoform X1 [Dendronephthya gigantea]
Species Eunicella cavolini · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSLDHT00000032721

atgacaagttttcatatgacaagttttatttgccaagtgcacgtgtgtatatgcaacatattttatatgacaagttttcatatgacaaTTTACTTTACTTACAATCCactgCCAATGAACTATGATGGTTTCAAACTATTTATGAATGCATATCTTGGCAATGACATCAGTGATgaattatgtcaacatttgttCTCGACATTTTGTAAACAAGTGCCAATAAACAATGCAGCAATAACAAGTTTACATAAATTGGTTAATTTAGCTGAAAGTGGCATACATACTGGTATTACATCGGCTGCGATAGTGGCTACAATTCCTATCACTTCACGAGATACAGCCGTTATTACGCATTCATCGTCACACACTCATTTAACTGGCACACCATGCAATGAAGTTGATCGCCTACCTCGCTCATCATCTGATGGTATAAATTGTGCATCTCGTATTATACCTGCTCGACGATCTATTATATCGCTAAACGGTAAACTAAATCAACACAATCTTACGATATTTAGCACGAAAAATGCCCTAGAAACTGTTGCCATGGTTTCAATACGCGAAATTGCGTGTTATTTGTCGTTACTTGAAGGAGGAGAAGTCGAGGATAAACTTGAATTTGTTTTTCGAGTGTATGATGCGGATGGTAACGAGTATCTTGATCAGCAGGAGTTGGAATCTATCACACAACAAATGATGAGTGTCGCCAGATATTTAGGATGGGATGTGACAGAATTGAAACCAATTTTGCAAGATATGTTGTTAGAACTAGATTGCGATTCAGATGGTCGTATATCACTCGATGAATGGATCAAAGGCGGTTTAACAACCATTCCGTTACTCGTATTGTTGGGTCTTGATCCGGTAAGTTTAAATATCAATTTCTGCAGATCTGCGAtgcttaaatattgttttgtcatttTAGTCTGCAAATTTACTGTTCATGAAAGATGTGTTAACAGAGTTCCCGCGTCTTGTATCAACACGTATGTTAAAACTAAAAGAACTGCAAAATTGACGATGGACCATCACTGGGTCGAGGGTAATTGTTCAGGAAAATGTCGGAAATGTGGCAAGACGATTAAAAATACTCACTCATTGTCAGGATTACACTGTGCTTGGTGTCATATCACGATTCACAATAAATGTGTTTCTCAAACACGGTTGGAATGTGATCTTGGTGAACACCGTGTTCATATTTTGCCGCCAACAAGTATTCATCCTGCTGGCATGGTGAGTTTCTATATATCTTGGGTGACCCCTCTACCCAACACGCATCCTCTGGCTGTATTTATCAACCCGAGAAGTGGCGGGCGTCAAGGAACGAGATTACTGTGGAAATTTCAATATCTTTTGAATCCAAGACAAGTATTTAATCTTGCAGACGGAGGGCCGACACCAGGGCTAAAATTTTTCTCGAGTGTGCCGAATTTTCATATCTTGTGTTGTGGTGGAGATGGCACCGCTGGTTGGGTTTTGGCATCTTTGGgtaagctatggaaatataaaaTTAATATTTATATGTTCAATTTATTTCAACTAGGAACTGGAAATGACCTATCTCGTTGTCTTCGTTGGGGTGGAGGTTATGAAGGAGAAAGGATTTCGAAAATTTTGAGTTCAGTGGAAAATAGCTCTATTGTCACCTTAGACAGGTTGGTATTAGACAGTGTGTTTAAAATTTATGAATCAGATGTAGCCGACCAGATCCCGTTAAACATCATCAATAATTACTGTTCAATTGGAGTGGATGCTTCGATTTCCCTCAACTTTCATCTTCAACGGGAAGCACATCCTGAGAAATTTAAAAGCAGGTTCATGAACAAGTTTCGTTATTTTGAATGTGGAACAACAGAGAACTTTTCTGCAACGTGCAAAAATCTTCATGAGAACCTTGAACTCATTTGTGATGGTAAGAAATTAAATCTGGCCTCTGGTCCAAGTTTAGAAGGCATTGCGATTCTGAATATCCCAAGTTATGCTGGTGGAACAAATCCTTGGGGAGAAGTCGATAAAAAGAAAgcaagaaagaaaaataagaaaGCAAAATGTAATGGAAAGGATGATCACGACTGGGCTGAACAAGATATCGGCGATGGTCTTATTGAAGTGGTTGGTTTTGAAAATGCTCTCTATGTGGGCCAAATCATTGCTGGTGTGAGAGCGCATGCGCTAAGACTAGCCCAATGTTCCACCGTTACAATAATAACTAAGAAATTGTTCCCAATACAAATCGACGGCGAACCTTGGATGCAGGCTCCAGCGACGATAAAAATCTCACATTTTAACCAAGTCCCGATGCTTCAAGGACCACTTCCGTCAAAGAAAGGTTTCTTTTCAAGACGTAAAGGAGAAGTAGAACAAGATTTGGAGACAGAATTATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9Y6T7	Diacylglycerol kinase beta OS=Homo sapiens OX=9606 GN=DGKB PE=1 SV=2
Q6NS52	Diacylglycerol kinase beta OS=Mus musculus OX=10090 GN=Dgkb PE=1 SV=2
P49621	Diacylglycerol kinase beta OS=Rattus norvegicus OX=10116 GN=Dgkb PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002468 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00781 all species →	DAGK_cat	Diacylglycerol kinase catalytic domain	Family	Interproscan
PF00130 all species →	C1_1	Phorbol esters/diacylglycerol binding domain (C1 domain)	Domain	Interproscan
PF00609 all species →	DAGK_acc	Diacylglycerol kinase accessory domain	Family	Interproscan
PF14513 all species →	DAG_kinase_N	Diacylglycerol kinase N-terminus	Domain	Interproscan
PF13499 all species →	EF-hand_7	EF-hand domain pair	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR018247 all species →	Binding_site	EF-Hand 1, calcium-binding site	Interproscan
IPR002219 all species →	Domain	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Interproscan
IPR001206 all species →	Domain	Diacylglycerol kinase, catalytic domain	Interproscan
IPR046349 all species →	Homologous_superfamily	C1-like domain superfamily	Interproscan
IPR000756 all species →	Domain	Diacylglycerol kinase, accessory domain	Interproscan
IPR002048 all species →	Domain	EF-hand domain	Interproscan
IPR037607 all species →	Family	Diacylglycerol kinase	Interproscan
IPR038199 all species →	Homologous_superfamily	DGK type I, N-terminal domain superfamily	Interproscan
IPR029477 all species →	Domain	Diacylglycerol kinase type I, N-terminal	Interproscan
IPR011992 all species →	Homologous_superfamily	EF-hand domain pair	Interproscan
IPR017438 all species →	Homologous_superfamily	Inorganic polyphosphate/ATP-NAD kinase, N-terminal	Interproscan
IPR016064 all species →	Homologous_superfamily	NAD kinase/diacylglycerol kinase-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11255 all species →	DIACYLGLYCEROL KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016301 all species →	Molecular Function	kinase activity	Interproscan
GO:0004143 all species →	Molecular Function	ATP-dependent diacylglycerol kinase activity	Interproscan
GO:0007205 all species →	Biological Process	obsolete protein kinase C-activating G protein-coupled receptor signaling pathway	Interproscan
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0046339 all species →	Biological Process	diacylglycerol metabolic process	Interproscan
GO:0046834 all species →	Biological Process	lipid phosphorylation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00901	dgkA, DGK; diacylglycerol kinase (ATP)	EC:2.7.1.107	Choline metabolism in cancer	ko05231	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →