Genomic Location: chr3:5547612...5570647
NR annotation: XP_028403832.1, general transcription and DNA repair factor IIH helicase subunit XPB-like [Dendronephthya gigantea]
Species Eunicella cavolini · all data for this species · gene families
| CDS |
| ENSLDHT00000035089 |
| Protein |
| ENSLDHP00000032331.1 |
| UniProt accession | Description |
|---|---|
| P19447 | General transcription and DNA repair factor IIH helicase/translocase subunit XPB OS=Homo sapiens OX=9606 GN=ERCC3 PE=1 SV=1 |
| Q60HG1 | General transcription and DNA repair factor IIH helicase/translocase subunit XPB OS=Macaca fascicularis OX=9541 GN=ERCC3 PE=2 SV=1 |
| Q5RA62 | General transcription and DNA repair factor IIH helicase/translocase subunit XPB OS=Pongo abelii OX=9601 GN=ERCC3 PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003957 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF16203 all species → | ERCC3_RAD25_C | ERCC3/RAD25/XPB C-terminal helicase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR050615 all species → | Family | ATP-dependent DNA Helicase | Interproscan |
| IPR001650 all species → | Domain | Helicase, C-terminal domain-like | Interproscan |
| IPR032438 all species → | Domain | ERCC3/RAD25/XPB helicase, C-terminal domain | Interproscan |
| IPR001161 all species → | Family | Helicase XPB/Ssl2 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11274 all species → | RAD25/XP-B DNA REPAIR HELICASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000112 all species → | Cellular Component | nucleotide-excision repair factor 3 complex | Interproscan |
| GO:0005675 all species → | Cellular Component | transcription factor TFIIH holo complex | Interproscan |
| GO:0006367 all species → | Biological Process | transcription initiation at RNA polymerase II promoter | Interproscan |
| GO:0043138 all species → | Molecular Function | 3'-5' DNA helicase activity | Interproscan |
| GO:0097550 all species → | Cellular Component | transcription preinitiation complex | Interproscan |
| GO:0003678 all species → | Molecular Function | DNA helicase activity | Interproscan |
| GO:0006289 all species → | Biological Process | nucleotide-excision repair | Interproscan |
ENSLDHP00000032331.1.Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
