Genomic Location: chr4:49367042...49370316
NR annotation: CAB3996786.1, sequestosome-1 isoform X2 [Paramuricea clavata]
Species Eunicella cavolini · all data for this species · gene families
| CDS |
| ENSLDHT00000036133 |
| Protein |
| ENSLDHP00000033330.1 |
| UniProt accession | Description |
|---|---|
| O08623 | Sequestosome-1 OS=Rattus norvegicus OX=10116 GN=Sqstm1 PE=1 SV=1 |
| Q64337 | Sequestosome-1 OS=Mus musculus OX=10090 GN=Sqstm1 PE=1 SV=1 |
| Q13501 | Sequestosome-1 OS=Homo sapiens OX=9606 GN=SQSTM1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003508 (this species only) · gene tree & orthology |
| Ubiquitin family | ULD|UFD|PB1 · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF16577 all species → | UBA_5 | UBA domain | Domain | Interproscan |
| PF00569 all species → | ZZ | Zinc finger, ZZ type | Domain | Interproscan |
| PF00564 all species → | PB1 | PB1 domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000433 all species → | Domain | Zinc finger, ZZ-type | Interproscan |
| IPR033741 all species → | Domain | Sequestosome-1, UBA domain | Interproscan |
| IPR000270 all species → | Domain | PB1 domain | Interproscan |
| IPR034866 all species → | Domain | Sequestosome-1, PB1 domain | Interproscan |
| IPR009060 all species → | Homologous_superfamily | UBA-like superfamily | Interproscan |
| IPR043145 all species → | Homologous_superfamily | Zinc finger, ZZ-type superfamily | Interproscan |
| IPR052260 all species → | Family | Autophagy Receptor and Signaling Regulator | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR15090 all species → | SEQUESTOSOME 1-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0008270 all species → | Molecular Function | zinc ion binding | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0000423 all species → | Biological Process | mitophagy | Interproscan |
| GO:0005080 all species → | Molecular Function | protein kinase C binding | Interproscan |
| GO:0007032 all species → | Biological Process | endosome organization | Interproscan |
| GO:0016235 all species → | Cellular Component | aggresome | Interproscan |
| GO:0035973 all species → | Biological Process | aggrephagy | Interproscan |
| GO:0044753 all species → | Cellular Component | amphisome | Interproscan |
| GO:0070530 all species → | Molecular Function | K63-linked polyubiquitin modification-dependent protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K14381 | SQSTM1; sequestosome 1 | - | Exosome | ko04147 | deepkoala |
Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |