Gene detail

Detailed information of ENSLDHP00000034216.1 in Eunicella cavolini

Genomic Location: not available for this species
NR annotation: CAB3993927.1, beta-secretase 1-like [Paramuricea clavata]
Species abbreviation ECAVO · all data for this species · gene families

Sequence

CDS

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q2HJ40	Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
P56819	Beta-secretase 1 OS=Rattus norvegicus OX=10116 GN=Bace1 PE=2 SV=1
P56818	Beta-secretase 1 OS=Mus musculus OX=10090 GN=Bace1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006562 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00026 all species →	Asp	Eukaryotic aspartyl protease	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR021109 all species →	Homologous_superfamily	Aspartic peptidase domain superfamily	Interproscan
IPR001969 all species →	Active_site	Aspartic peptidase, active site	Interproscan
IPR033121 all species →	Domain	Peptidase family A1 domain	Interproscan
IPR009120 all species →	Family	Beta-secretase BACE1	Interproscan
IPR001461 all species →	Family	Aspartic peptidase A1 family	Interproscan
IPR009119 all species →	Family	Beta-secretase BACE	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR47965 all species →	ASPARTYL PROTEASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004190 all species →	Molecular Function	aspartic-type endopeptidase activity	Interproscan
GO:0006508 all species →	Biological Process	proteolysis	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0005768 all species →	Cellular Component	endosome	Interproscan
GO:0005802 all species →	Cellular Component	trans-Golgi network	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006509 all species →	Biological Process	membrane protein ectodomain proteolysis	Interproscan
GO:0050435 all species →	Biological Process	amyloid-beta metabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04521	BACE1; beta-site APP-cleaving enzyme 1 (memapsin 2)	EC:3.4.23.46	Peptidases and inhibitors	ko01002	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.