Gene detail

Detailed information of ENSLDHP00000040742.1 in Eunicella cavolini

Genomic Location: chr5:137412...142815
NR annotation: CAB3995971.1, ATP-binding cassette sub-family B member 7, mitochondrial [Paramuricea clavata]
Species Eunicella cavolini · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSLDHT00000044574

atgGCTGCGAAAATAACCAATATTCGTTCTTGCTGTGGTTTGCTAAATTATCGATATTGCACAAGAAATATTGTTTCTTTTACTCATCGAGGATTGCTTTCTAGCCCTTATGTACAAGCTAAGGTAAAATTTAGTCACGATTTGTATTGTAAATGGCAGTTATTGGGCTATTGCAATTTTATTAAGTCACACCCCCTCCCCTGCGGCCCTCCAAGCCTGTACTTCTACCGTACTGCACAAAGAAATCATTTACCTTCATCTCAAGCAATTGACAACAAAAAAAAGCCACAAATCACAAACAGTTTGAGCATAATCAAAAGTATGTTACATCATGTGTGGCCAAAGGATCGAAATGATTTGAAGATTAGAGTTGTACTTGCAATTTCATTACTTGTTGGATCTAAGGTTTTAAATGTCCAAGTGCCATTTTTATTCAAATATGCAGTTGATCATCTGAATAATGCTGCAACTTTAGTGGACAGTGTAGCTGGTACGACGATGACACTGACAACAGCAGTACTGCTTGGATATGGGGCGGCAAGAGCTGGTTCATCACTTTTTAATGAATTAAGAAATGCTGTGTTTGCTAAAGTAGCACAAAGCTCTATCAGAACTGTTGCAAAAAGAACATTCTTGCATTTACATAATCTTGATCTAAATTTCCATCTTTCGAGGCAAACCGGTGCTCTGTCAAGAGCAATTGATAGAGGAACAAGAGGTATCAACTTTATGCTAACTGCGTTAGTATTCAATATTTTCCCAACATTATTAGAAGTTTCACTGGTCACTGGAATTTTGGCATATAAATGTGGTAAAGAATTTGCCTTGGTAACATTAACATGTATAGCTGGTTATACTTTCTTTACCTTTGGGATTACTCAATGgcggacaaaatttcgtgtcgAAATGAACAAGGCAGATAATGAGGCAGGGTCATTAGCAATTGACTCATTGCTCAACTACGAAACTGTTAAGTATTTCAACAATGAACAGCACGAAGCAAACAGATATGACAAATTATTAGAAAACTACGAAAAAGCATCGTTGAAAACTAGCACAAGTTTATCAATGTTAAATTTTGGTCAGAACGCGATATTTAGTACTTCTCTAGTTGCAGTCATGTTGTGTGCTAGCAGTCAAATTACAGCAGGAACAATGACTGTTGGAGATCTAGTGATGGTCAATGGTCTTTTATTTCAACTTTCATTGCCTTTGAATTTCCTTGGCACTGTTTATCGTGAAATACGTCAATCCTTGGTTGACATGCAGGCGTTATTTGATCTGCGCAATGTTAAATCGCAAGTAACGGTATGTAAACCAGATGCATTTCCTCTCATCCTCAAGCCAGGAGATCGCAATGCTCATGTGCGATTTGAAGACGTCCACTTCAGTTACGTTGATGGTCAGAAGATTTTGGATGGATTAAGTTTTGATGTCCCATCTGGAAAGAAAATTGCAATCGTTGGTGGAAGTGGTTCAGGGAAATCAACAGTTATTCGTTTAATAAACCGTTTCTTTGATCCTTCCGATGGACGAATATTGGTAGCTGGACACGACACTCGGGATCTGTCGTTGGACAGTCTACGCCAGGCTTTGGGCATTGTTCCACAGGACTCAGTGTTATTCCACAACACGGCTTTCTACAACATCAACTACGGAAGAATTGATGCAACCACTAACGAAGTTTACGAAGCCGCGAGACTGGCGGACATTCACGACCAAATCCGACGATGGCCGGATGGTTACGACACTCAGGTCGGCGAACGAGGTCTGAAGTTATCGGGAGGGGAAAAACAACGTATCGCTATTGCTAGAGCGATATTGAAGAAACCACCAATACTACTTTATGATGAGGCTACATCGTCTTTGGATTCAATAACTGAAAtgAACATACTACAAGCATTACATCGGTTCACCAAGGACCGAACATCAATAGTGATCGCACATCGATTGTCCACAGTACTGGATGCTGACGAGATCTTGGTGCTGGAACGCGGGCGCGTCAGAGAACGTGGTCGTCATGACGACCTACTGAAGGACACTTCCGGTCTCTATGCGTACCTTTGGAGCAAACAGTCGCAGGGATACTCTAGGACTGAGGGGGATATGACATCTGAGTCAGGGTTAGATAGttaa

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
E7F6F7	Iron-sulfur clusters transporter ABCB7, mitochondrial OS=Danio rerio OX=7955 GN=abcb7 PE=3 SV=1
H2LNR5	Iron-sulfur clusters transporter ABCB7, mitochondrial OS=Oryzias latipes OX=8090 GN=abcb7 PE=1 SV=2
O75027	Iron-sulfur clusters transporter ABCB7, mitochondrial OS=Homo sapiens OX=9606 GN=ABCB7 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001433 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00664 all species →	ABC_membrane	ABC transporter transmembrane region	Family	Interproscan
PF00005 all species →	ABC_tran	ABC transporter	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036640 all species →	Homologous_superfamily	ABC transporter type 1, transmembrane domain superfamily	Interproscan
IPR017871 all species →	Conserved_site	ABC transporter-like, conserved site	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR011527 all species →	Domain	ABC transporter type 1, transmembrane domain	Interproscan
IPR039421 all species →	Family	Type 1 protein exporter	Interproscan
IPR003439 all species →	Domain	ABC transporter-like, ATP-binding domain	Interproscan
IPR003593 all species →	Domain	AAA+ ATPase domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24221 all species →	ATP-BINDING CASSETTE SUB-FAMILY B	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0016887 all species →	Molecular Function	ATP hydrolysis activity	Interproscan
GO:0055085 all species →	Biological Process	transmembrane transport	Interproscan
GO:0140359 all species →	Molecular Function	ABC-type transporter activity	Interproscan
GO:0005743 all species →	Cellular Component	mitochondrial inner membrane	Interproscan
GO:0006879 all species →	Biological Process	intracellular iron ion homeostasis	Interproscan
GO:0016021 all species →	Cellular Component	membrane	Interproscan
GO:0042626 all species →	Molecular Function	ATPase-coupled transmembrane transporter activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K05662	ABCB7, ATM; ATP-binding cassette, subfamily B (MDR/TAP), member 7	-	Transporters	ko02000	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →