Gene detail

Detailed information of ENSLDHP00000042649.1 in Eunicella cavolini

Genomic Location: chr6:6171896...6270707
NR annotation: XP_028393342.1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like isoform X1 [Dendronephthya gigantea]
Species Eunicella cavolini · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSLDHT00000046721

ATGGATATAGCCATGCAAATATGGAATATTGCTGTACCAAATTTACTTCAATCCGGGACAATTTTGCATAAATGGGATGAGGAGTCTAGTGGAGTACACGAATGTCATTTTACCGTCGATCGATACGGCTTTTTTCTTGCATTTCGTGAAGCCGAAAAGGAACCATCGTGTGTTGATTTGGCTAATGTGACCGAAGTGAAACTCGGTGGAGTACTACCTAagGGCGTGAAACGATTTGTTGAATATGAAAGATTACTTTATAGTGATGGAAAGGCACGAAGCAGCCTCGAGTGTAGTGGTCCTGAGCCAATCAAGGAACGAGTGTTTACTGTTATTATTTCACAAAATCTTGTCGAGACAACATCCATATACCTCTGCTCCAGCTCATCAAGAGTTGCGAGGGAATGGGTTGAAGGCTTGCAGCAACTGTGCAATTCCGTTAAAGCTACTAACTTGAGTGTTATGACAATGCTTTTAAAATTatACACCAAGGCAACGTCGTTAAAAGTCAATGGAAAGATTTCAGTTAGAAGCATCTGTAAATGTTTTAACTGtggcaaaaattatgagaaACGAATCCTGGATGGTTTACAAGCTATGGACCTTCCTCATGAAAAGAATGAAGAAATAGACCAGAGCTTATTCACGTTCGAGAAATTATATCAACTGTATGCGAAAGTTTGTCCAAGACAAGATTTTGATCaaatttttactaaatgGCAAGCCGGTAAAGCACCGTATTTATCTCCAACAAGATTCATGGAATTTATAAATGCTGAACAACGCGATCCTAGTGCGAATGAAATCTTGCATCCTCACTGTAATAAAGAAAAAGCCATAAAGATTATCAGCAAATATGAGAAATGTCGAGAAATGGTAAAACAAGggCGCATGAGTGCGGATGGTTTATCTCGTTATTTGATGTCTGATGAAAATCTTTGCGTCAAGTCAGAAGTATTTGAAGTTCATCAAGATATGAATCAACCTCTTTCTCATTATTTTATCAATTCCTCGCATAACACGTATTTAACAGGGAGGCAGATCGGTGGAAAATCGTCTGTAGAAATATATCGTCAGTGTTTGCTAAGTGGCTGTCGGTGCATTGAGTTAGATTGCTGGGATGGTCCAGGGGATGAGCCTATCATTACCCATGGCAAAGCAATGTGCACTAATATCATGTTTAAGGATGTTATTGAAGCTATTAAAGAAACTGCTTTCGTAACCTCGGAATATCCACTTTTACTTTCGTTTGAAAATCATTGCAGTAAGTACCAGCAGTATAAAATGGCGTGTTACTGCACAGAAATATTTGGAGATCTGTTGTTAGCTTCACCGCTCGATTCTCATCCGTTGGAGGAAAATCAACCATTACCATCACCGAATCTTTTAAAGCGAAAGATTCTAATAAAGAATAAGAAATTACGACCCGGTCAGGAGTCGAACTACGACACAGATAGCATGGCATCTTCAGACAGCCGTAAATCCAGCGAAGTTCGACTTGAAGACATCAAGAATGTTCGGCCCCGGATGTCACGACTGTCAGAGGATTTTGACGGTGAAGAGGCGGCGTTGAAAGGAGAGGATGGTGGTTTTGTCAatattttaaaagaagaaaaaactTTACGTTCATCGATAACTTCCGATAGAAGCAGCAACCATAATATGTTCGATAAACGAAGACATAACTTTAGACAGAGACGAAAACACTCCTTAGATGACACGTCGAAACGATTGAACGGTTGTATAGCTGAGGAGGGTCAGACACATGGGCGGACCTCAGACACAGATGAACAAAATATGAACGGTGATAACGTTACAAATGCTCTGGAAGCTTTCGATGAAATGATCATGGACATTGACTCGGATTCCAGTGACTCCAAAGAGGACGAAGATAAAGATTGTATATTAATGTCAAATATTTGTCTCACTGAGCACGAGGGGATGTATCCGACATTAAGTAAAGATACAAGAACGACGTGCTTACCCCCTGAAGTGGAGTTAATGACGATGAGAAAAAGTTCGACGGCGAGTACAGACTCCGCACAGTCTGACGATGAACGCGATGTGAAACGGAGTGAAAGTTTTGCTTCGTTTGGAAGTTCTGTTAAAATTGTCCAACAACGACAGAATTCTCAGAGCAGTATTGATGAGGTGGCAGAATATTTGGCGAACTACCATCATTCCGCATCGCTTGGCAACATTCATCCCAGTCTGTCATGTCTGGTAAACTACACACAACCCATACCATTCCCAGGCTTTGAGAGATCAGAAGaaactAACCATCATTATCTGATGTCTTCATTCAATGAAGTTGCCGCATTCACACTTCTCAAAGGAAATCCAGTCGAGTTTGTCAAGTATAACCAACGGCAATTATCGCGAATATATCCTAAAGGAAGTCGTGTTGATTCCAGTAACTACATGCCACAGGTGTTTTGGAATGCTGGTAGTCAGATGGTTGCATTAAATCTCCAAACGACAGATCTCGCGTTTCAGTTGAATACTGGCAAATTTGTTGATAACGGGCGATGCGGATATTTATTAAAGCCGTCTGTGATGAGAAAAAGTGACAAAAATTTCGATCCATTTACGGAACTGCCAGTGGACGGGGTGGTAGCAACGTGTATTACCATCAAGGTGATTTCAGGTCAATTCTTGTCGGATAAAAGAGTTGGAACGTACGTGGAAGTAGATTTATATGGCTTACCAACGGACACCGTTAGAAAGAAATTTAAAACTAAAATTATTAACAGCAACGGAATGAATCCTGCGTATGATAGTGAAGAGTTCTCATTTAAGAGGattGTTCTACCAGAGCTTGCCTTACTTCGTTTTACGGTGCTTGACGACAGTGACCGAATACTTGGACAGCGAGTTATTCCTGTCAGTTCTATTCAACCAGGATATCGTCACATTCCACTGTGGACCGAAGGATGTCGTCCTCTTCCTCTCTCCACGTTATTTTGTCATATATCACTCAATGTTTATGTGTTTGAAGGATTCTCCGATGTTGTTGACGAATTATCTCAACCAATCAAACACCAGTCTGCTGTGGAGAAAAGAGCAGAAGCCATTTGTAGGATATTTGATTTTGAAGAGGACTATGATGATGTTGACACTATTCCTCCGAACACGAATGGATTTAGTCAGAAATCTCCGAAAAACTCCTACAATTCGTTACCGGTGGTTAATTTTCCTCCCAACAACAGAAGAGAGTCAACAGTTACTTTGAGTTTGTCCTCATCTGCGTCAAGCTTGCAGTTCAATACCGCCTGGTTTGATCGAGTGCCCACACAGCtTAAAAGTAATCTAGAGCCAGTTGACATCGAAGAATTAAAGAAAGACAAGGTTTTTACTAAATTATTGAAGAAACATCAAAAGGAATCGGACACTTTAACAAAACGACTAGTGAAGGAGCGAACAACACTAAGTAAATCACACAATGCAGCTTTAGAGAAGCTGTTTGTGAACGCGcagaaaaataaagaaaatgagAAGAAAACGTTTGAGAGAGCAAAGAAAAAATGCAGTGGCAGTGATCTGGTACAGCTTCAGAATGTCCACGAGCAAAAGTTGGCGTATCTTACCACAGTACAACAACAACAGGTAAAAGCAGTGTTGAACCAGCAGTCTGACGAATGGTGCAATCTAATATCACAGCAAGTTAATGAGGAGCTTGATTTATATGACATTCACTCTCCGCAGAGATTATCGCTATTAAAGAAGTTACTGGATGGAGCCCATGACGGTCAGTTGAAAACAATGGAGTCCCGACATGAAAGAGAATGCGTGGACCTGCGTAAGAATCAGGTGAAACAGTCTGTAGAGACGTCGAAAAATGCTGGCAAACAGATCAAGTGCAAAGAAGAGAAAGAGAGGATGTTACGAGAGTTAGACAGAATCAATATCAAGGATTTTCTTGAGGAAAGACAGCAGCTTGAAAACAGACAAGCAAAGGAAGTTGAAGAATTGAAGAATTTTCATAAAAAAGAATGGGAACAAGTTGATATTAACTTTCAAAAGGAGGTAAAAGAACACAAGGACGAGATCAGGCTGGGTGAAGAAGCTTTAAGGAAACCATTCTTGTTTTCATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q15147	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3
Q9QW07	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Rattus norvegicus OX=10116 GN=Plcb4 PE=1 SV=2
Q07722	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (Fragment) OS=Bos taurus OX=9913 GN=PLCB4 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001136 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00387 all species →	PI-PLC-Y	Phosphatidylinositol-specific phospholipase C, Y domain	Family	Interproscan
PF06631 all species →	DUF1154	Protein of unknown function (DUF1154)	Family	Interproscan
PF09279 all species →	EF-hand_like	Phosphoinositide-specific phospholipase C, efhand-like	Domain	Interproscan
PF17787 all species →	PH_14	PH domain	Domain	Interproscan
PF00388 all species →	PI-PLC-X	Phosphatidylinositol-specific phospholipase C, X domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR035892 all species →	Homologous_superfamily	C2 domain superfamily	Interproscan
IPR001711 all species →	Domain	Phospholipase C, phosphatidylinositol-specific, Y domain	Interproscan
IPR000008 all species →	Domain	C2 domain	Interproscan
IPR016280 all species →	Family	Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta	Interproscan
IPR009535 all species →	Conserved_site	Phospholipase C-beta, conserved site	Interproscan
IPR001192 all species →	Family	Phosphoinositide phospholipase C family	Interproscan
IPR015359 all species →	Domain	Phosphoinositide-specific phospholipase C, EF-hand-like domain	Interproscan
IPR017946 all species →	Homologous_superfamily	PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily	Interproscan
IPR042531 all species →	Homologous_superfamily	Phospholipase C-beta, C-terminal domain superfamily	Interproscan
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR011992 all species →	Homologous_superfamily	EF-hand domain pair	Interproscan
IPR037862 all species →	Domain	PLC-beta, PH domain	Interproscan
IPR000909 all species →	Domain	Phosphatidylinositol-specific phospholipase C, X domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10336 all species →	PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004435 all species →	Molecular Function	phosphatidylinositol phospholipase C activity	Interproscan
GO:0006629 all species →	Biological Process	lipid metabolic process	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0008081 all species →	Molecular Function	phosphoric diester hydrolase activity	Interproscan
GO:0048015 all species →	Biological Process	phosphatidylinositol-mediated signaling	Interproscan
GO:0051209 all species →	Biological Process	release of sequestered calcium ion into cytosol	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K05858	PLCB; phosphatidylinositol phospholipase C, beta	EC:3.1.4.11	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →