Genomic Location: chr7:1903634...1915626
NR annotation: XP_028393942.1, apoptotic protease-activating factor 1-like [Dendronephthya gigantea]
Species Eunicella cavolini · all data for this species · gene families
| CDS |
| ENSLDHT00000047165 |
| Protein |
| ENSLDHP00000043060.1 |
| UniProt accession | Description |
|---|---|
| O14727 | Apoptotic protease-activating factor 1 OS=Homo sapiens OX=9606 GN=APAF1 PE=1 SV=2 |
| Q9EPV5 | Apoptotic protease-activating factor 1 OS=Rattus norvegicus OX=10116 GN=Apaf1 PE=1 SV=1 |
| O88879 | Apoptotic protease-activating factor 1 OS=Mus musculus OX=10090 GN=Apaf1 PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004173 (this species only) · gene tree & orthology |
| Ubiquitin family | UBD|Other|Beta-prp · all ubiquitin genes in this species |
| Ubiquitin family | E3|E3 adaptor Cullin RING|CDC20 · all ubiquitin genes in this species |
| Ubiquitin family | E3|E3 adaptor Cullin RING|DWD · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00619 all species → | CARD | Caspase recruitment domain | Domain | Interproscan |
| PF00931 all species → | NB-ARC | NB-ARC domain | Domain | Interproscan |
| PF21296 all species → | APAF-1-like_WHD | Apoptotic protease-activating factor 1-like, winged-helix domain | Domain | Interproscan |
| PF17908 all species → | APAF1_C | APAF-1 helical domain | Domain | Interproscan |
| PF00400 all species → | WD40 | WD domain, G-beta repeat | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011029 all species → | Homologous_superfamily | Death-like domain superfamily | Interproscan |
| IPR042197 all species → | Homologous_superfamily | Apoptotic protease-activating factors, helical domain | Interproscan |
| IPR001680 all species → | Repeat | WD40 repeat | Interproscan |
| IPR019775 all species → | Conserved_site | WD40 repeat, conserved site | Interproscan |
| IPR001315 all species → | Domain | CARD domain | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR002182 all species → | Domain | NB-ARC | Interproscan |
| IPR036388 all species → | Homologous_superfamily | Winged helix-like DNA-binding domain superfamily | Interproscan |
| IPR048975 all species → | Domain | Apoptotic protease-activating factor 1, winged-helix domain | Interproscan |
| IPR041452 all species → | Domain | APAF-1 helical domain | Interproscan |
| IPR015943 all species → | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| IPR036322 all species → | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR020472 all species → | Repeat | G-protein beta WD-40 repeat | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22845 all species → | APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0042981 all species → | Biological Process | regulation of apoptotic process | Interproscan |
| GO:0043531 all species → | Molecular Function | ADP binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K02084 | APAF1; apoptotic protease-activating factor | - | Platinum drug resistance | ko01524 | deepkoala |
Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
