Genomic Location: chr8:16523495...16551699
NR annotation: XP_028396479.1, pre-mRNA-processing-splicing factor 8 [Dendronephthya gigantea]
Species Eunicella cavolini · all data for this species · gene families
| CDS |
| ENSLDHT00000049165 |
| Protein |
| ENSLDHP00000044795.1 |
| UniProt accession | Description |
|---|---|
| Q99PV0 | Pre-mRNA-processing-splicing factor 8 OS=Mus musculus OX=10090 GN=Prpf8 PE=1 SV=2 |
| Q6P2Q9 | Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 |
| P34369 | Pre-mRNA-splicing factor 8 homolog OS=Caenorhabditis elegans OX=6239 GN=prp-8 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004368 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08082 all species → | PRO8NT | PRO8NT (NUC069), PrP8 N-terminal domain | Domain | Interproscan |
| PF10598 all species → | RRM_4 | RNA recognition motif of the spliceosomal PrP8 | Domain | Interproscan |
| PF10597 all species → | U5_2-snRNA_bdg | U5-snRNA binding site 2 of PrP8 | Domain | Interproscan |
| PF01398 all species → | JAB | JAB1/Mov34/MPN/PAD-1 ubiquitin protease | Family | Interproscan |
| PF10596 all species → | U6-snRNA_bdg | U6-snRNA interacting domain of PrP8 | Domain | Interproscan |
| PF08084 all species → | PROCT | PROCT (NUC072) domain | Domain | Interproscan |
| PF08083 all species → | PROCN | PROCN (NUC071) domain | Domain | Interproscan |
| PF12134 all species → | PRP8_domainIV | PRP8 domain IV core | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR027652 all species → | Family | Pre-mRNA-processing-splicing factor 8 | Interproscan |
| IPR012591 all species → | Domain | PRO8NT domain | Interproscan |
| IPR019582 all species → | Domain | RNA recognition motif, spliceosomal PrP8 | Interproscan |
| IPR037518 all species → | Domain | MPN domain | Interproscan |
| IPR000555 all species → | Domain | JAB1/MPN/MOV34 metalloenzyme domain | Interproscan |
| IPR021983 all species → | Domain | PRP8 domain IV core | Interproscan |
| IPR042516 all species → | Homologous_superfamily | Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily | Interproscan |
| IPR043172 all species → | Homologous_superfamily | Prp8 RNase domain IV, palm region | Interproscan |
| IPR019581 all species → | Domain | Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding | Interproscan |
| IPR019580 all species → | Domain | Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding | Interproscan |
| IPR043173 all species → | Homologous_superfamily | Prp8 RNase domain IV, fingers region | Interproscan |
| IPR012337 all species → | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR012984 all species → | Domain | PROCT domain | Interproscan |
| IPR012592 all species → | Domain | PROCN domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11140 all species → | PRE-MRNA SPLICING FACTOR PRP8 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000244 all species → | Biological Process | spliceosomal tri-snRNP complex assembly | Interproscan |
| GO:0000398 all species → | Biological Process | mRNA splicing, via spliceosome | Interproscan |
| GO:0005681 all species → | Cellular Component | spliceosomal complex | Interproscan |
| GO:0005682 all species → | Cellular Component | U5 snRNP | Interproscan |
| GO:0017070 all species → | Molecular Function | U6 snRNA binding | Interproscan |
| GO:0030619 all species → | Molecular Function | U1 snRNA binding | Interproscan |
| GO:0030620 all species → | Molecular Function | U2 snRNA binding | Interproscan |
| GO:0030623 all species → | Molecular Function | U5 snRNA binding | Interproscan |
| GO:0071013 all species → | Cellular Component | catalytic step 2 spliceosome | Interproscan |
| GO:0097157 all species → | Molecular Function | pre-mRNA intronic binding | Interproscan |
| GO:0003723 all species → | Molecular Function | RNA binding | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0008233 all species → | Molecular Function | peptidase activity | Interproscan |
| GO:0008237 all species → | Molecular Function | metallopeptidase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K12856 | PRPF8, PRP8; pre-mRNA-processing factor 8 | - | Spliceosome | ko03041 | deepkoala |
Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |