Detailed information of ENSLDHP00000045066.1 in Eunicella cavolini

Genomic Location: chr9:334688...336799
NR annotation: CAB3990105.1, dihydrofolate reductase-like [Paramuricea clavata]
Species Eunicella cavolini · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P28019Dihydrofolate reductase OS=Aedes albopictus OX=7160 GN=DHFR PE=3 SV=1
P00377Dihydrofolate reductase OS=Sus scrofa OX=9823 GN=DHFR PE=1 SV=1
Q920D2Dihydrofolate reductase OS=Rattus norvegicus OX=10116 GN=Dhfr PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002489 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00186
all species →		DHFR_1Dihydrofolate reductaseDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR024072
all species →		Homologous_superfamilyDihydrofolate reductase-like domain superfamilyInterproscan
IPR001796
all species →		DomainDihydrofolate reductase domainInterproscan
IPR017925
all species →		Conserved_siteDihydrofolate reductase conserved siteInterproscan
IPR012259
all species →		FamilyDihydrofolate reductaseInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR48069
all species →		DIHYDROFOLATE REDUCTASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004146
all species →		Molecular Functiondihydrofolate reductase activityInterproscan
GO:0046654
all species →		Biological Processtetrahydrofolate biosynthetic processInterproscan
GO:0005739
all species →		Cellular ComponentmitochondrionInterproscan
GO:0046452
all species →		Biological Processdihydrofolate metabolic processInterproscan
GO:0046655
all species →		Biological Processfolic acid metabolic processInterproscan
GO:0050661
all species →		Molecular FunctionNADP bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K00287DHFR, folA; dihydrofolate reductaseEC:1.5.1.3
Antifolate resistanceko01523deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix–
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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