Gene detail

Detailed information of ENSLDHP00000048361.1 in Eunicella cavolini

Genomic Location: chr9:160178...168309
NR annotation: CAB4008695.1, Adenomatous polyposis coli [Paramuricea clavata]
Species Eunicella cavolini · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSLDHT00000053061

ATGGAGAACGGGCAGGATGAGATCGAAGATGACATATTTGAACATCACATGCATGAAATAGACGAACGAGAAACACCAAGATGGGAAATGTCAGAAGAAGAGCCAGATGGAGAGGAGGAAGAGACAAGAATATTGAACTGTGATGGTCTGCCAAAACAACCAGCTCAACAGaatTCCATTCCAAGTAAGAAAGCTGAGATTGTCCAGAATGGTCAAACATGGGATGATCTTTCTGAGCACGACTCAGTAAAGGATTTCACTGGACCGTATCGTGAAAAAGAAGCAAAGTATATGGAGAGAACCGATGAAGCAATTTTTAACCGAGCATCTGAAGAACATATACGTCAACCTATTCCTTATGATGATGTTGACTCGGTTAAGAATTTTGGTGGGGCAAGTCAAGGTATCAGTCGCATACCCTCAGAAGAACAACTTTGTCTCTCACCACCCTGGCCACATGGGTATGAAGTAGATGATGGGATACCTTTAGAGGACAGTAAAATTGCAGAGGCCATACCAACTGAGGGAAACAACTATTGTGTTGATGACATGATATCACAAGCCAAGTTGCAAGCTGATGCTAGGGTTGGAAGTTCCACCACTTGGCAACAAGAGGATTTTACTCGGAATTATGCAGAAGAAGGTTCTTTGGAGAATTCCCGACGTCCTTCCTCAGAAGATATATCCTTGACTCCACCTTGGCTAGATACTGATAAAGAATCATCTTGCAAGGATGCCGACGAACAAATTTTAGATGACAGTGAACTTCCATCTGCAGATCCACCAACAACCAGTTCAACCCTCACACATACACCAACAACAACACATACCCCATCACCCAAAACTGATCCCCTTCCCTCTGTCACCAAGCCACCGCTGATTGAAAGCCCTCATGCTGTAAAAAGAACACCAACTGTCCAGCCTGATCCAACAAGTGTACCTGGAAATAGTTCAAAATCCCTCCCTCCACAAAGACATACCCCACAAGGACCAACTTCTGATCGGAACAATGTATGTGTAAACCCCGTACCATCACGACTGCCACAAATGAAGCCTTATGGTGAGGTATATAACAATAGAAACCCACCACCCCACAAACCTTATCAAGCTAATGATCCCTACTATGATCCTTCTAAGATGGGAGCCATACCTTTACCTTACTCGGTAAACCCACATTACACTAACAATCTCCCCAATGCCCGAACGTCCTACCCTATGCTTCGCCCTGGTGTAAAATATCAATCAAATTTAAAATCGTACAATGGAATGCCGCCATTTAATCTTCGTCAATATCGACCAAGACCTCAAGAAATTGCCAACAGACCCCAAATAAACCCTACAAATCCATCATTTTCAAATATACCCCACCCATACCCCAATGGTGGCTACTACAACCCAACCCACGCTCCGAGGACAGGGACACCTCGTCAGGTAATGAACAGATATGAGTTACCTTACTACGGTCCACGAACAGGCGACTGGCAATACCAAGTTAGACAACCTCAAATACCAATTCAAACCCAACCCCCTCCTCTAAACACGACTGATTTTGCGGAGGATGAAGTCATTAACTTTGCCGCAGAAGCGAAGCGGATTTTGGCACCATCTGATCGATCCAGAACGGCACCCGATGTAGTTAATCGAAATATGCCAGCTTCAGAACATCAACGGGGAGTACCCGAGGTACATCGTAATATACCCGTATCCGAAATGCAACGTAATGTTCCAGAGTTCCATCGTGGTGTTCCGGATTTCCATCGTGATGTTTCGGATTTCCATCGTGATGTCCCGGCATTCCGTCGAGACATCACAGCTGCCGACAACCGCCGAGGTATTCCAGATCATCAGCACGCAGTACCAGACTTCCCACCCAACATTCTTAATAAAGGAATCTATTCAGACTTCCCCGATGATATCACGACAGTTTCCGACAGCGACGTCAGTCCTGTGATGTCGACACGAACCGGAAGTCAATCAAGTCTTGCTGTGTACTGTCATACACCAAATCGAGATGAAACAGCCAGCGTTATGAGCTTCACAAGTGGGGCGTCTACACATCAAGACCTAGACTCAAAAATTGATCAAGTTAGAAACCTTTTGGCAGTCATAGACACACGAGACGCGAAGGAGACAGCACGGACTTTGTACAGCCTTTCAAATTCCAAAGAAAACTGTCAGGCTATGAGATTATCTGGTTGTTTGCCACTCCTAATACAACTTCAGCATAAATCAAAAACGCGGGACCCACGTGTAGCACAGGAAGTTCGCCTGAGGTCGGCGCAGACGATTAGGAACATCATACAGGCAGGGATAGAGGATAAACGTGGAAAAAGAGAACTTCGCGTGCTCACGCTGATTGAGGTCGTGCGCAATTATTGTACCGAGGTTCGTTATGTTCGTAACGTTTCTAGCTCGTCTAAAATTGGTGCACTAAATAACGCGTTAGCTGCTATTATGAAGCTCTCTTTTGAAGAGGAACATCGACTTGCTATTGGGGACCTTGGCGGAGTCGAAGCCATTGGTGAATTCTTGGAACTTGGTTATGTTAACAAAGACGGACATCTCTCATTGGGCAACAACGTCCGTAAGTACGCCTCGATGACTTTAACAAATATGACGTTTGAGAAGACCCGCAGTAAGGCGTTGCTAGGAAACTCTGAAGGAATCGTCAAAGCTTTACTGAAGAACCTAATTGTATTAAATGACGAAGACCTTATCCAGGTCTCTGCGAGTGTTCTTCGGAATCTATCGTGTAAATCGGACGAACGAAGTAAAATGGTTTTACAGGAATGCAATGCGGTCTCAGATTTGATGACTGCTGCCCAGAAGGTTAGCGGTGAATCAACCTTACGTACGATACTTTATGCAGTTTGGAACTTATCTGCTCATAGCTCAGAGAATAAAGTTAAGATATGTGAGACTAACAAAGCACTTGGATTTTTGGTAGAAATGTTGGCGTTTAAAAGTCCTAGTAATTCTCTCACAGTCGTTGAAAGCAGCGGCGGAATATTGCGCAATTTATCATCACAGATCGCAGTGAAATCTGAGTACCGTGCGACGTTGCGTGAACAcgaatgttttaaatttttgctcGTGAATTTACGTTCTCCCAGTCTGCGTGTTGTAGGAAACGCGTGCGGAATATTATGGAATTTGTCAGCACGCTGCGAAACGGATCAGGAAATACTTCTTAAAATGGGTGCACTTGCTTTGCTTAAACCTCTCGTCACgtcaaaaaataaattaattgccAAAGGAGCTGGAGCTGCCATCAAGAACTTGCAGAATTATAAAACTGCTAATCCAGGTCGTGATTCACCGTCAGAGACGCGTAAACAGAACGGAATTCTTCGCCAAGAGAACGGATCACCTTCGACACCTCGAACAAAAGGAAAGTCGCGTGACGCACATTCATTGAATAGCTTTACTGGAAGTGCAGATGACATGACGAAGGAAAATGCAAAACAGGGTTCACGCACTAAAGAGAATGGTGAAGCTGACTCAGGGAATACAAGAAAAATTGTACGTTGGTCAGACGACAAACGAAAAGATCCACAACGAAAAACGTCAAACGATCGAAAACGAGGCGATAGTTCCCCGGATGAACAACAGACCGCGCAAACCTCAAGAGACTTGGGAACAAGGGAAAGTGTGGATGACGTGACAAACGGTGTTGGACAGCTACGTATTGGAGAAAAATCCCGGAGCAGAAAGTCTGAGAGTTCGTATTCCTCGCCACGAACTAAGAAGAAATCTAACTCCAAGACTAAGAAACATCATTCAGGAGGCGATAACGTAATTGACGAGAATTTACGGTTGTCGCAAGAGTCTCAGTTAAATCGGTCGACATCAAGTCGTCAAGATTCGGCTAATGGTCGGCGTCATGCGTCGTCTGACATTCAACACCCGGAAACATTTGCAAAGCATGCAGGGCAAGTGACAAAGGGTAAAGATGGACGGAAAGGAATATCAGGGGCTCGCGAAGATGGTCCAGAAGTGCCACGATCTGAAGACGACAGTTCACGAAACTCTCCAATGTCTGGCCGACACAATATTAGAAGCCGCCTTGATTCCGAAGATAACGATCGTGGTTTCAACGACGAGGCAAGGGATCCAGGGTCACAGCGGTGTCGGTGCGCTGACGACTCAGAGGTGTGGGTCAAGAGAAATAAAATCTGCAGTCATTGTCAGAAAAGACGAGTGTCGCACTCTTCTGATTCCACGAGCGGCTCTCGACGAAGTTCATACGAGTCTTTGTCGTCGTCAAACCGGCAGCTTAATCGGAAAGAACCACTAACTAACGGAACAGGCTACGTCACAACAATATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P25054	Adenomatous polyposis coli protein OS=Homo sapiens OX=9606 GN=APC PE=1 SV=2
Q61315	Adenomatous polyposis coli protein OS=Mus musculus OX=10090 GN=Apc PE=1 SV=1
P70478	Adenomatous polyposis coli protein OS=Rattus norvegicus OX=10116 GN=Apc PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005491 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF18797 all species →	APC_rep	Adenomatous polyposis coli (APC) repeat	Repeat	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR011989 all species →	Homologous_superfamily	Armadillo-like helical	Interproscan
IPR026818 all species →	Family	Adenomatous polyposis coli (APC) family	Interproscan
IPR000225 all species →	Repeat	Armadillo	Interproscan
IPR041257 all species →	Repeat	Adenomatous polyposis coli (APC) repeat	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12607 all species →	ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0001708 all species →	Biological Process	cell fate specification	Interproscan
GO:0005881 all species →	Cellular Component	cytoplasmic microtubule	Interproscan
GO:0007026 all species →	Biological Process	negative regulation of microtubule depolymerization	Interproscan
GO:0007389 all species →	Biological Process	pattern specification process	Interproscan
GO:0007399 all species →	Biological Process	nervous system development	Interproscan
GO:0008013 all species →	Molecular Function	beta-catenin binding	Interproscan
GO:0008017 all species →	Molecular Function	microtubule binding	Interproscan
GO:0016342 all species →	Cellular Component	catenin complex	Interproscan
GO:0016477 all species →	Biological Process	cell migration	Interproscan
GO:0030178 all species →	Biological Process	negative regulation of Wnt signaling pathway	Interproscan
GO:0030877 all species →	Cellular Component	beta-catenin destruction complex	Interproscan
GO:0045295 all species →	Molecular Function	gamma-catenin binding	Interproscan
GO:0045595 all species →	Biological Process	regulation of cell differentiation	Interproscan
GO:0045732 all species →	Biological Process	positive regulation of protein catabolic process	Interproscan
GO:0090090 all species →	Biological Process	negative regulation of canonical Wnt signaling pathway	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for ENSLDHP00000048361.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella cavolini tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella cavolini, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →