Genomic Location: :...
NR annotation: CAB4026853.1, serine threonine- kinase endoribonuclease IRE1 [Paramuricea clavata]
| CDS | ||||
| ENSNOVT00005005433 | ||||
| Transcript |
| ENSNOVT00005005433 |
| Protein |
| ENSNOVP00005005433.1 |
| Uniprot term | Description |
|---|---|
| Q5ZJJ2 | Replication protein A 70 kDa DNA-binding subunit OS=Gallus gallus OX=9031 GN=RPA1 PE=2 SV=1 |
| P27694 | Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 |
| Q6NY74 | Replication protein A 70 kDa DNA-binding subunit OS=Danio rerio OX=7955 GN=rpa1 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF04057 | Rep-A_N | Replication factor-A protein 1, N-terminal domain | Domain | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF06479 | Ribonuc_2-5A | Ribonuclease 2-5A | Family | Interproscan |
| PF16900 | REPA_OB_2 | Replication protein A OB domain | Domain | Interproscan |
| PF01336 | tRNA_anti-codon | OB-fold nucleic acid binding domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR045133 | Family | Serine/threonine-protein kinase/endoribonuclease IRE1/2-like | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR012340 | Homologous_superfamily | Nucleic acid-binding, OB-fold | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR007199 | Domain | Replication factor-A protein 1, N-terminal | Interproscan |
| IPR010513 | Domain | KEN domain | Interproscan |
| IPR031657 | Domain | Replication protein A, OB domain | Interproscan |
| IPR004365 | Domain | OB-fold nucleic acid binding domain, AA-tRNA synthetase-type | Interproscan |
| IPR038357 | Homologous_superfamily | KEN domain superfamily | Interproscan |
| IPR004591 | Family | Replication factor A protein 1 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13954 | IRE1-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004521 | Molecular Function | RNA endonuclease activity | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0030968 | Biological Process | endoplasmic reticulum unfolded protein response | Interproscan |
| GO:0036498 | Biological Process | IRE1-mediated unfolded protein response | Interproscan |
| GO:0051082 | Molecular Function | unfolded protein binding | Interproscan |
| GO:0070059 | Biological Process | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | Interproscan |
| GO:1990604 | Cellular Component | IRE1-TRAF2-ASK1 complex | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0003677 | Molecular Function | DNA binding | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006260 | Biological Process | DNA replication | Interproscan |
| GO:0004540 | Molecular Function | RNA nuclease activity | Interproscan |
| GO:0006397 | Biological Process | mRNA processing | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0006281 | Biological Process | DNA repair | Interproscan |
| GO:0006310 | Biological Process | DNA recombination | Interproscan |