Genomic Location: chr15:9332979...9336802
NR annotation: CAB3981104.1, Phosphonopyruvate decarboxylase [Paramuricea clavata]
Species Eunicella verrucosa · all data for this species · gene families
| CDS |
| ENSNOVT00005018523 |
| Transcript |
| ENSNOVT00005018523 |
| Protein |
| ENSNOVP00005016331.1 |
| UniProt accession | Description |
|---|---|
| O86938 | Phosphonopyruvate decarboxylase OS=Streptomyces viridochromogenes (strain DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494) OX=591159 GN=ppd PE=1 SV=1 |
| Q54271 | Phosphonopyruvate decarboxylase OS=Streptomyces hygroscopicus OX=1912 GN=bcpC PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005667 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02775 all species → | TPP_enzyme_C | Thiamine pyrophosphate enzyme, C-terminal TPP binding domain | Domain | Interproscan |
| PF02776 all species → | TPP_enzyme_N | Thiamine pyrophosphate enzyme, N-terminal TPP binding domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011766 all species → | Domain | Thiamine pyrophosphate enzyme, TPP-binding | Interproscan |
| IPR017684 all species → | Family | Phosphonopyruvate decarboxylase | Interproscan |
| IPR029061 all species → | Homologous_superfamily | Thiamin diphosphate-binding fold | Interproscan |
| IPR012001 all species → | Domain | Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain | Interproscan |
| IPR051818 all species → | Family | Thiamine pyrophosphate-dependent decarboxylase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR42818 all species → | SULFOPYRUVATE DECARBOXYLASE SUBUNIT ALPHA | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003824 all species → | Molecular Function | catalytic activity | Interproscan |
| GO:0030976 all species → | Molecular Function | thiamine pyrophosphate binding | Interproscan |
| GO:0032923 all species → | Biological Process | organic phosphonate biosynthetic process | Interproscan |
| GO:0033980 all species → | Molecular Function | phosphonopyruvate decarboxylase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K09459 | E4.1.1.82; phosphonopyruvate decarboxylase | EC:4.1.1.82 | Biosynthesis of various antibiotics | ko00998 | deepkoala |
Transcript abundance of ENSNOVP00005016331.1 across 21 RNA-seq samples of Eunicella verrucosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole tissue | 21 | 14 | 3.05 | 10.83 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| ERR11252245 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 10.83 |
| ERR11252240 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 8.61 |
| ERR11252242 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 7.57 |
| ERR11252244 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 5.00 |
| ERR11252257 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 4.89 |
| ERR11252249 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 4.43 |
| ERR11252256 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 3.97 |
| ERR11252243 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 3.84 |
| ERR11252262 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 2.91 |
| ERR11252254 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 2.77 |
| ERR11252255 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 2.67 |
| ERR11252260 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 2.47 |
| ERR11252261 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 2.07 |
| ERR11252246 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 1.99 |
| ERR11252248 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 0.00 |
| ERR11252250 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 0.00 |
| ERR11252251 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 0.00 |
| ERR11252252 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 0.00 |
| ERR11252253 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 0.00 |
| ERR11252258 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 0.00 |
| ERR11252259 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (EVERR_TPM,
StringTie quantification over 21 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Eunicella verrucosa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 19 | ENSNOVP00005023904.1 | -0.682432956429996 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Eunicella verrucosa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
