Genomic Location: chr3:8174331...8176319
NR annotation: CAB4000324.1, Replication factor C subunit 3 [Paramuricea clavata]
Species Eunicella verrucosa · all data for this species · gene families
| CDS |
| ENSNOVT00005031526 |
| Transcript |
| ENSNOVT00005031526 |
| Protein |
| ENSNOVP00005027770.1 |
| UniProt accession | Description |
|---|---|
| Q8R323 | Replication factor C subunit 3 OS=Mus musculus OX=10090 GN=Rfc3 PE=1 SV=1 |
| Q2TBV1 | Replication factor C subunit 3 OS=Bos taurus OX=9913 GN=RFC3 PE=2 SV=1 |
| P40938 | Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0006718 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF03215 all species → | Rad17 | Rad17 P-loop domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR050238 all species → | Family | DNA Replication and Repair Clamp Loader Complex | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11669 all species → | REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003689 all species → | Molecular Function | DNA clamp loader activity | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005663 all species → | Cellular Component | DNA replication factor C complex | Interproscan |
| GO:0006261 all species → | Biological Process | DNA-templated DNA replication | Interproscan |
| GO:0006281 all species → | Biological Process | DNA repair | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10756 | RFC3_5; replication factor C subunit 3/5 | - | DNA repair and recombination proteins | ko03400 | deepkoala |
Transcript abundance of ENSNOVP00005027770.1 across 21 RNA-seq samples of Eunicella verrucosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole tissue | 21 | 21 | 23.42 | 42.34 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| ERR11252251 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 42.34 |
| ERR11252259 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 37.46 |
| ERR11252258 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 37.09 |
| ERR11252250 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 36.83 |
| ERR11252256 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 33.67 |
| ERR11252242 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 30.99 |
| ERR11252255 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 27.44 |
| ERR11252248 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 26.42 |
| ERR11252246 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 25.91 |
| ERR11252243 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 24.95 |
| ERR11252249 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 24.69 |
| ERR11252260 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 23.25 |
| ERR11252245 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 21.03 |
| ERR11252261 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 19.46 |
| ERR11252240 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 18.19 |
| ERR11252254 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 15.23 |
| ERR11252262 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 15.11 |
| ERR11252253 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 10.50 |
| ERR11252257 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 9.31 |
| ERR11252244 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 6.27 |
| ERR11252252 | whole tissue | whole tissue | polyp | not recorded | ERP146504 | 5.60 |
Source: CnidoSite RNA-seq expression matrices (EVERR_TPM,
StringTie quantification over 21 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Eunicella verrucosa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 16 | ENSNOVP00005015925.1 | -0.839980610321278 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Eunicella verrucosa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |