Detailed information of ENSNOVP00005027770.1 in Eunicella verrucosa

Genomic Location: chr3:8174331...8176319
NR annotation: CAB4000324.1, Replication factor C subunit 3 [Paramuricea clavata]
Species Eunicella verrucosa · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q8R323Replication factor C subunit 3 OS=Mus musculus OX=10090 GN=Rfc3 PE=1 SV=1
Q2TBV1Replication factor C subunit 3 OS=Bos taurus OX=9913 GN=RFC3 PE=2 SV=1
P40938Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0006718 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF03215
all species →
Rad17Rad17 P-loop domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR050238
all species →
FamilyDNA Replication and Repair Clamp Loader ComplexInterproscan
IPR027417
all species →
Homologous_superfamilyP-loop containing nucleoside triphosphate hydrolaseInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11669
all species →
REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNITInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003689
all species →
Molecular FunctionDNA clamp loader activityInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0005663
all species →
Cellular ComponentDNA replication factor C complexInterproscan
GO:0006261
all species →
Biological ProcessDNA-templated DNA replicationInterproscan
GO:0006281
all species →
Biological ProcessDNA repairInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K10756RFC3_5; replication factor C subunit 3/5-DNA repair and recombination proteinsko03400deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSNOVP00005027770.1 across 21 RNA-seq samples of Eunicella verrucosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples
21TPM > 0
1Conditions
42.3Max TPM
23.4Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole tissue 21 21 23.42 42.34

Per sample · hover a bar for the full sample record

Show the sample table (21 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR11252251 whole tissue whole tissue polyp not recorded ERP146504 42.34
ERR11252259 whole tissue whole tissue polyp not recorded ERP146504 37.46
ERR11252258 whole tissue whole tissue polyp not recorded ERP146504 37.09
ERR11252250 whole tissue whole tissue polyp not recorded ERP146504 36.83
ERR11252256 whole tissue whole tissue polyp not recorded ERP146504 33.67
ERR11252242 whole tissue whole tissue polyp not recorded ERP146504 30.99
ERR11252255 whole tissue whole tissue polyp not recorded ERP146504 27.44
ERR11252248 whole tissue whole tissue polyp not recorded ERP146504 26.42
ERR11252246 whole tissue whole tissue polyp not recorded ERP146504 25.91
ERR11252243 whole tissue whole tissue polyp not recorded ERP146504 24.95
ERR11252249 whole tissue whole tissue polyp not recorded ERP146504 24.69
ERR11252260 whole tissue whole tissue polyp not recorded ERP146504 23.25
ERR11252245 whole tissue whole tissue polyp not recorded ERP146504 21.03
ERR11252261 whole tissue whole tissue polyp not recorded ERP146504 19.46
ERR11252240 whole tissue whole tissue polyp not recorded ERP146504 18.19
ERR11252254 whole tissue whole tissue polyp not recorded ERP146504 15.23
ERR11252262 whole tissue whole tissue polyp not recorded ERP146504 15.11
ERR11252253 whole tissue whole tissue polyp not recorded ERP146504 10.50
ERR11252257 whole tissue whole tissue polyp not recorded ERP146504 9.31
ERR11252244 whole tissue whole tissue polyp not recorded ERP146504 6.27
ERR11252252 whole tissue whole tissue polyp not recorded ERP146504 5.60

Source: CnidoSite RNA-seq expression matrices (EVERR_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella verrucosa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated0not in this network-
Negatively correlated16ENSNOVP00005015925.1-0.839980610321278

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella verrucosa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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