Detailed information of ENSNOVP00005029167.1 in Eunicella verrucosa

Genomic Location: chr4:15758479...15759689
NR annotation: CAB3994125.1, E3 ubiquitin- ligase NRDP1-like [Paramuricea clavata]
Species Eunicella verrucosa · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q9UPQ7E3 ubiquitin-protein ligase PDZRN3 OS=Homo sapiens OX=9606 GN=PDZRN3 PE=1 SV=2
P68907E3 ubiquitin-protein ligase PDZRN3 OS=Rattus norvegicus OX=10116 GN=Pdzrn3 PE=1 SV=1
Q69ZS0E3 ubiquitin-protein ligase PDZRN3 OS=Mus musculus OX=10090 GN=Pdzrn3 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001310 (this species only) · gene tree & orthology
Ubiquitin familyE3|E3 activity RING|U-box · all ubiquitin genes in this species

 Pfam domain
No Pfam domain signature was recorded for ENSNOVP00005029167.1 in Eunicella verrucosa.
 InterPro
InterPro termTypeDescriptionSource
IPR001293
all species →
DomainZinc finger, TRAF-typeInterproscan
IPR051438
all species →
FamilyRNF E3 ubiquitin-protein ligaseInterproscan
IPR001841
all species →
DomainZinc finger, RING-typeInterproscan
IPR013083
all species →
Homologous_superfamilyZinc finger, RING/FYVE/PHD-typeInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR46016
all species →
ZINC FINGER, RING/FYVE/PHD-TYPEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0008270
all species →
Molecular Functionzinc ion bindingInterproscan
GO:0000209
all species →
Biological Processprotein polyubiquitinationInterproscan
GO:0006511
all species →
Biological Processubiquitin-dependent protein catabolic processInterproscan
GO:0061630
all species →
Molecular Functionubiquitin protein ligase activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for ENSNOVP00005029167.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSNOVP00005029167.1 across 21 RNA-seq samples of Eunicella verrucosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

21Samples
1TPM > 0
1Conditions
9.4Max TPM
0.4Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole tissue 21 1 0.45 9.42

Per sample · hover a bar for the full sample record

Show the sample table (21 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR11252253 whole tissue whole tissue polyp not recorded ERP146504 9.42
ERR11252240 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252242 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252243 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252244 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252245 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252246 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252248 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252249 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252250 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252251 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252252 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252254 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252255 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252256 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252257 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252258 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252259 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252260 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252261 whole tissue whole tissue polyp not recorded ERP146504 0.00
ERR11252262 whole tissue whole tissue polyp not recorded ERP146504 0.00

Source: CnidoSite RNA-seq expression matrices (EVERR_TPM, StringTie quantification over 21 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Eunicella verrucosa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated50ENSNOVP00005016921.11
Negatively correlated3ENSNOVP00005019896.1-0.550756138916537

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Eunicella verrucosa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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