Gene detail

Detailed information of ENSODKP00000011534.1 in Millepora complanata

Genomic Location: chr15:98160565...98306201
NR annotation: XP_013384434.1, multiple epidermal growth factor-like domains protein 6 [Lingula anatina]
Species Millepora complanata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSODKT00000012502

AAACAGGTTACTGCAGTAAATTGTCGTAAATTTAGCTCCATGCTATTGCTTTATAATTCAGTTTTACTTCTTTTAACGTTTTTCTTTAATCCAACTTCTGTAGAAGGTCAAAGGCTGGTAAGAAATGGagtAAATGTTTGCAACAGAACATATTCGCAACAACAACAGTACACAGTATCGGTTCGGTATTCTGTACGTCAATACTCTAGGTACATTTCAAGAGTGCGGTACGACCGTAGAACAAGACGCACTTACCGAACAGAATATGTATGCTGCAGTGGATATGAACAATCTGGCACTGGATGTCCTATACCAATATGTGATGGTTGTGTCCATGGAGAATGTATTGGACCATACATTTGCAGTTGTAATTCCGGATATCGTGGCTTGAGATGTAATGAAGATGTAAACGAGTGTGAAACATTAAATGGAGGCTGCGATCATCAGTGCGACAATACTATTGGTAGCTTCAATTGCAAATGCACAGAAGGATTTTTGTTAGATGGGAATGGAAAAACCTGTATAGAGTACGATGAGTGCAATATTACGGATCATGGATGCCAACAAATATGTGTGAATATGTCTGGGAGTTTTTTTTGTGCATGCCGAAGTGGATATCAGTTAAACGCTGACAATAAGACTTGTTCAGATATTAATGAATGTCAAATGTTCAATGACTTGTGTCAGCATCGATGCATAAATGCAAATGGTATCTACGTGTGTCAGTGCAACATGGACTGCTCAGCATTAGAATCTACATTAACTGACAAACTGAAATTTATAATAGAAGAAAATGCGATAGCATCATCCTTTCCAGTACAACAAATACAACACTACAACAACGAACACCGAACGAACACTACAACAAATGGCAGCGAAGTGGTAAGAAAACGTCGATATATTTATGATGTAAGACACGATAAAGCGGGAATAACGAAAAGAATTAAAAGAGCTGGCTACATTACTCCAACATTGGCTAATTTTGGGACAGGTTTACCTCAAGGCACGACATTTACTTCCCATTATTGTGCAAAAAGAAGAGACAATTGTGTATCCAATACATTTAAAACATGCCCAGAATGTGTTTACACTTTAACCATGCCTCAAACGTATTACCCACGCATGCATCGTGCTGTCCTATGCACAGACGGCAATGACAAGTCTTGCTTGAGTGGTGGAGGCACATGCGTCTCCAACCAGAATGTCATCAGATTACTACATGATAATCGAAATTTAGGGATCAAAAGGTTAGGTAAATGGCAAGTAATTATGGTGCAAATAGCAAAAAGCTGTTCATGTAAAATATTCAGGAAGTCTacgtttgaagtttttgtataACAAAAACTTCTATGAAAATAGACAAAACATATAACGAGTAATGGagttatgtttttatattttatgaagtaatatgttttttgaataattagTGTGGTTCCACATCCACTGAGTGGAAGAAGGAAAAGTATCGGCCACTGCGtgaaaatctccgtattcagttcgaatacgggGAAATAggacatttttcacacagtgGGTTTTCTAAACATTACAAGCATATATGATAATTTAGCATTATTCCAAAGCAAATTCTGCAAAGCAGCGCTAATATTTTGATTAGAGTGTGGTTTGTTGCAATTTATAGAAAACTTTCAGTCAGTCGTTTATCATATAGGTAAGAAGAACAAAATCCAGAGTTAAAGAACTATATCAAAACCTAAGAGATGATCTTTTAGATAGGTTTCCTTGTAAAATGTTAGCAATAACATTTCAAGTGATTTACATAACATAATTCTGAATTACTTGTCCTCTCATCCATAATGAAACGAGACACATTTTTTCACACATTATTTTAAGTAAGGCCCAGGAAATAGATGGTTAGGGTTCGAAAATAAACCGGTAAATTTTTGCTTCTTAAAATTAACTCTAAAGGTTGATTCTGACTGTTAGTCCTTCATTTCTTTTTAGTTTACTtgacattgaaaaatttttaacaaaaaaagacctTACAAGAACCCAATTTTTAACCAACTATTGCTAACTGGTGTTTACATAAGAAGGTATCCTGGaaatgttaatattgattatgtcGTAATACATTTTGAAAAGCTTAAGCCTTCATATACCGCAGATTTTGCTATTTGTCACTTATCTGACTAGATCCCATATCCGACATTCAAAAGCCGAATGCTAGTTTTGGTGAATCGTTTGTCTTGTAAGCATTAACTTAACTTTAGATTTGAAGTTGAATAAGCCGGAGAGAACCCTAATTCACGTTACATTTTCCCGGCGTTAAGCATAGGCTCTAAACGTTTCTATAATGTAATCGCCGTGATT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O75095	Multiple epidermal growth factor-like domains protein 6 OS=Homo sapiens OX=9606 GN=MEGF6 PE=1 SV=4
P25723	Dorsal-ventral patterning protein tolloid OS=Drosophila melanogaster OX=7227 GN=tld PE=2 SV=2
O57382	Tolloid-like protein 2 OS=Xenopus laevis OX=8355 GN=tll2 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007457 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF12662 all species →	cEGF	Complement Clr-like EGF-like	Domain	Interproscan
PF14670 all species →	FXa_inhibition	Coagulation Factor Xa inhibitory site	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000742 all species →	Domain	EGF-like domain	Interproscan
IPR026823 all species →	Domain	Complement Clr-like EGF domain	Interproscan
IPR000152 all species →	PTM	EGF-type aspartate/asparagine hydroxylation site	Interproscan
IPR011489 all species →	Domain	EMI domain	Interproscan
IPR018097 all species →	Conserved_site	EGF-like calcium-binding, conserved site	Interproscan
IPR001881 all species →	Domain	EGF-like calcium-binding domain	Interproscan
IPR009030 all species →	Homologous_superfamily	Growth factor receptor cysteine-rich domain superfamily	Interproscan
IPR050751 all species →	Family	Extracellular matrix structural protein	Interproscan
IPR029034 all species →	Homologous_superfamily	Cystine-knot cytokine	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24034 all species →	EGF-LIKE DOMAIN-CONTAINING PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for ENSODKP00000011534.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Millepora complanata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Millepora complanata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →