Genomic Location: :...
NR annotation: XP_047132970.1, DNA topoisomerase 2-alpha isoform X2 [Hydra vulgaris]
| CDS | ||||
| ENSODKT00000013717 | ||||
| Transcript |
| ENSODKT00000013717 |
| Protein |
| ENSODKP00000012525.1 |
| Uniprot term | Description |
|---|---|
| P41515 | DNA topoisomerase 2-alpha OS=Cricetulus griseus OX=10029 GN=TOP2A PE=2 SV=1 |
| O46374 | DNA topoisomerase 2-alpha OS=Sus scrofa OX=9823 GN=TOP2A PE=2 SV=1 |
| P11388 | DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00204 | DNA_gyraseB | DNA gyrase B | Domain | Interproscan |
| PF02518 | HATPase_c | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001241 | Family | DNA topoisomerase, type IIA | Interproscan |
| IPR013506 | Domain | DNA topoisomerase, type IIA, subunit B, domain 2 | Interproscan |
| IPR036890 | Homologous_superfamily | Histidine kinase/HSP90-like ATPase superfamily | Interproscan |
| IPR003594 | Domain | Histidine kinase/HSP90-like ATPase | Interproscan |
| IPR014721 | Homologous_superfamily | Small ribosomal subunit protein uS5 domain 2-type fold, subgroup | Interproscan |
| IPR050634 | Family | DNA Topoisomerase II Enzyme | Interproscan |
| IPR020568 | Homologous_superfamily | Ribosomal protein uS5 domain 2-type superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10169 | DNA TOPOISOMERASE/GYRASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003677 | Molecular Function | DNA binding | Interproscan |
| GO:0003918 | Molecular Function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006265 | Biological Process | DNA topological change | Interproscan |
| GO:0000712 | Biological Process | resolution of meiotic recombination intermediates | Interproscan |
| GO:0000819 | Biological Process | sister chromatid segregation | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |