Gene detail

Detailed information of ENSODKP00000021764.1 in Millepora complanata

Genomic Location: chr2:179738416...179756310
NR annotation: XP_002164975.1, rho-related BTB domain-containing protein 1 [Hydra vulgaris]
Species Millepora complanata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSODKT00000023678

atggCAAACGATTTACTTGAAAGAGCACGTGTGTCTTTGGATGCATACGATGAACAGCCACGCCAAGAGTACGTAAAATGTGTAGTTGTGGGGGATACAGCAGTTGGAAAAACAAGGTTAATATGCTCTTATGTTTATGATCAACCAGGATTGTCAATCCCATCAGTCAGTCAAAGGGCACATATTCCAACAGTCTTTGCAATTGATCAGTATGTGGCTGAtccaaacattagaaaaagagcaaaattgtttttacatGGTGTTCAGGCTCAGCTTCGCATTTGGGATACTTTTGGAGATCatgagaaaaacagaaaatttgccTACCAAAATGCGCATGTAGTGGTGTTATGTTTTAGTATAGGAATGCGATCTTCATTGCGTAATGTGAATGCAAATTGGTATccagagataaaaaaatattgtccaaGAGCCCCAATCATTCTTGTTGGGACTCAGTTGGATCGACGACATACTGATCCATgtgcatttaaaaatttgtcaaatataacAACCCTGACAGATATTTTAAACAACAATATGGGCACAAAAAAAAGGAGTAGTAAATTACCCCAGTCAGACAAATGTACCCCACCAGAGGATGGTCGCCAACTAGCCAGGGAAATTAATGCAGCAGTTTATATGGAAGCAAGTGTGGTAACTAAGCATGGGGTAAATGAAGTATTTGAAAATGCAGTACGAGTAGCTTTGATAAATAGGCGGCAATCTAAACCATTGTTTAGTTCTCATCTCAAAAGGGTGAAGAATCCTTCTCCACAAAAACCATATTTACCAACAAGGCCAGATCCAACAAGAATTGttataccaatgaaaaatgatagcATAGAAACTATCCCAAATGAAATTGATACTTTTTGTGATGTCACATTCTTGGTTGATCATGAACTGATTTATGCTCACAGCGTGGTTTTAATATCAGGTTCACACGTGTTTTCACGACTTTTAAACCATCCAGATGTACTTAATGTTTTAGGGTACACAAACTTTATCCCAGAAACTGAGGAAGAACGAGTTAAATCTACAAAAGGTTTTATCAATGGTGTTTTAGTTGATGGTGTACCTTTTGGATTTGAAACAATAGATGTTTTGTCAGATCCACAAGAGACCTGTAAAGTATTTGTGAAAGTCAAAAATGTTTCGGCACAAGATTTCAAAAGCATCATAGAATTTATATATACAGGTAAAATATGTTTAGCCAAGGATCCAATAAATTTGTTGcaagtttgtaataatttatcaCTAGATCAAACTTGCAGttatctgaaaaatatattaaatggtgaaaattttttaaattttgaagttcaAAGTGACTTACAAAGGAGGAAAATTCGaagatatatcaaatattttttcaaaaaacaattatatgCTGATTGTGCATTTATTGTTGATGGAATAGCAATACCAGCACATAAGTATATTCTGGTCTCTCATTGTTCAATAATGGAGGGAATGTTTCaaaataatttcaaggaGAGCTTATCAAATCAGGTGGATTTTCACGATACGAGTTATGATAGTTTCATAGCAGTATTAGAATATTTATACACTGGTACATGTGAGAAGTATAACGACCTGCATGGTACTTTGCAACTGGCCAACTTTTTGTGTCTCCCAAGGCTGGTAGCGTTATGTGAATCGGAAATTGTCAACTacattaaagaaataacagatagAAACAGTAGAGAATACACAATCCCTCCCTCTTACAAACTCGCTCAGTTTCATAACGCTCCACAGTTATCAGCTTGGTGTCTGCATTTCATGGCAACCAATTACAATGCCCTTTGCAAAGAACAAAGTCAAGAAATGAAATCGCTAGATACAGAAACGTtacaatatcttgagaagaacCGATGGCCTCCTGTGTGGTATTTGAAAGAGCAAGATTATTACGAACGCACCATGGCTCAGTTAGAGcgagaaaaaaatcttaaaaagaaaaagaagcaaaggCGAAAGTACAGTGGATGTTTCTGA

Transcript

ENSODKT00000023678

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O94844	Rho-related BTB domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RHOBTB1 PE=1 SV=2
Q91V93	Rho-related BTB domain-containing protein 2 OS=Mus musculus OX=10090 GN=Rhobtb2 PE=2 SV=2
Q9BYZ6	Rho-related BTB domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RHOBTB2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0008020 (this species only) · gene tree & orthology
Ubiquitin family	E3\|E3 adaptor Cullin RING\|BTB · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00651 all species →	BTB	BTB/POZ domain	Domain	Interproscan
PF00071 all species →	Ras	Ras family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011333 all species →	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	Interproscan
IPR000210 all species →	Domain	BTB/POZ domain	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR001806 all species →	Family	Small GTPase	Interproscan
IPR005225 all species →	Domain	Small GTP-binding protein domain	Interproscan
IPR003578 all species →	Family	Small GTPase Rho	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24072 all species →	RHO FAMILY GTPASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0003924 all species →	Molecular Function	GTPase activity	Interproscan
GO:0005525 all species →	Molecular Function	GTP binding	Interproscan
GO:0005856 all species →	Cellular Component	cytoskeleton	Interproscan
GO:0007163 all species →	Biological Process	establishment or maintenance of cell polarity	Interproscan
GO:0007264 all species →	Biological Process	small GTPase-mediated signal transduction	Interproscan
GO:0008360 all species →	Biological Process	regulation of cell shape	Interproscan
GO:0019901 all species →	Molecular Function	protein kinase binding	Interproscan
GO:0030865 all species →	Biological Process	cortical cytoskeleton organization	Interproscan
GO:0031410 all species →	Cellular Component	cytoplasmic vesicle	Interproscan
GO:0032956 all species →	Biological Process	regulation of actin cytoskeleton organization	Interproscan
GO:0042995 all species →	Cellular Component	cell projection	Interproscan
GO:0043652 all species →	Biological Process	engulfment of apoptotic cell	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K07868	RHOBTB1_2; Rho-related BTB domain-containing protein 1/2	-	GTP-binding proteins	ko04031	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Millepora complanata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Millepora complanata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →