Detailed information of ENSODKP00000038996.1 in Millepora complanata

Genomic Location: chr9:83442234...83468723
NR annotation: XP_002164867.1, 3-methyl-2-oxobutanoate dehydrogenase [lipoamide] kinase, mitochondrial [Hydra vulgaris]
Species Millepora complanata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
O14874Branched-chain alpha-ketoacid dehydrogenase kinase OS=Homo sapiens OX=9606 GN=BCKDK PE=1 SV=2
O55028Branched-chain alpha-ketoacid dehydrogenase kinase OS=Mus musculus OX=10090 GN=Bckdk PE=1 SV=1
Q00972Branched-chain alpha-ketoacid dehydrogenase kinase OS=Rattus norvegicus OX=10116 GN=Bckdk PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0006476 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02518
all species →
HATPase_cHistidine kinase-, DNA gyrase B-, and HSP90-like ATPaseDomainInterproscan
PF10436
all species →
BCDHK_Adom3Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinaseFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR036784
all species →
Homologous_superfamilyAlpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamilyInterproscan
IPR003594
all species →
DomainHistidine kinase/HSP90-like ATPaseInterproscan
IPR039028
all species →
FamilyPDK/BCKDK protein kinaseInterproscan
IPR018955
all species →
DomainBranched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminalInterproscan
IPR036890
all species →
Homologous_superfamilyHistidine kinase/HSP90-like ATPase superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11947
all species →
PYRUVATE DEHYDROGENASE KINASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004672
all species →
Molecular Functionprotein kinase activityInterproscan
GO:0004740
all species →
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) kinase activityInterproscan
GO:0005739
all species →
Cellular ComponentmitochondrionInterproscan
GO:0006468
all species →
Biological Processprotein phosphorylationInterproscan
GO:0010906
all species →
Biological Processregulation of glucose metabolic processInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K00898PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4EC:2.7.11.2
Protein kinasesko01001deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Millepora complanata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Millepora complanata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
TOP