Gene detail

Detailed information of ENSOFVP00000004023.1 in Cyphastrea salae

Genomic Location: :...
NR annotation: PFX26489.1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [Stylophora pistillata]

Gene Structure

More details in Jbrowse

Sequence

CDS

Transcript

Protein

Uniprot

Uniprot term	Description
P60483	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Canis lupus familiaris OX=9615 GN=PTEN PE=2 SV=1
P60484	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Homo sapiens OX=9606 GN=PTEN PE=1 SV=1
O08586	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN OS=Mus musculus OX=10090 GN=Pten PE=1 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF10409	PTEN_C2	C2 domain of PTEN tumour-suppressor protein	Domain	Interproscan
PF06951	PLA2G12	Group XII secretory phospholipase A2 precursor (PLA2G12)	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR029023	Domain	Tensin-type phosphatase domain	Interproscan
IPR014020	Domain	Tensin phosphatase, C2 domain	Interproscan
IPR016130	Active_site	Protein-tyrosine phosphatase, active site	Interproscan
IPR000387	Domain	Tyrosine-specific protein phosphatases domain	Interproscan
IPR051281	Family	Dual-specificity lipid and protein phosphatase	Interproscan
IPR036444	Homologous_superfamily	Phospholipase A2 domain superfamily	Interproscan
IPR003595	Domain	Protein-tyrosine phosphatase, catalytic	Interproscan
IPR035892	Homologous_superfamily	C2 domain superfamily	Interproscan
IPR010711	Family	Group XII secretory phospholipase A2 precursor	Interproscan
IPR045101	Domain	PTEN, phosphatase domain	Interproscan
IPR029021	Homologous_superfamily	Protein-tyrosine phosphatase-like	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12305	PHOSPHATASE WITH HOMOLOGY TO TENSIN	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0016311	Biological Process	dephosphorylation	Interproscan
GO:0004725	Molecular Function	protein tyrosine phosphatase activity	Interproscan
GO:0005634	Cellular Component	nucleus	Interproscan
GO:0005829	Cellular Component	cytosol	Interproscan
GO:0005886	Cellular Component	plasma membrane	Interproscan
GO:0006470	Biological Process	protein dephosphorylation	Interproscan
GO:0008285	Biological Process	negative regulation of cell population proliferation	Interproscan
GO:0014065	Biological Process	obsolete phosphatidylinositol 3-kinase signaling	Interproscan
GO:0016314	Molecular Function	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	Interproscan
GO:0042995	Cellular Component	cell projection	Interproscan
GO:0046856	Biological Process	phosphatidylinositol dephosphorylation	Interproscan
GO:0048870	Biological Process	cell motility	Interproscan
GO:0051896	Biological Process	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Interproscan
GO:0004623	Molecular Function	phospholipase A2 activity	Interproscan
GO:0006644	Biological Process	phospholipid metabolic process	Interproscan
GO:0050482	Biological Process	arachidonate secretion	Interproscan
GO:0005509	Molecular Function	calcium ion binding	Interproscan
GO:0005576	Cellular Component	extracellular region	Interproscan
GO:0016042	Biological Process	lipid catabolic process	Interproscan
GO:0016791	Molecular Function	phosphatase activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K01110	PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	EC:3.1.3.16 EC:3.1.3.48 EC:3.1.3.67	Protein phosphatases and associated proteins	ko01009	deepkoala