Genomic Location: not available for this species
NR annotation: XP_020605984.1, thioredoxin reductase 1, cytoplasmic-like isoform X1 [Orbicella faveolata]
Species abbreviation CSALA · all data for this species · gene families
| CDS |
| ENSOFVT00000006517 |
| Transcript |
| ENSOFVT00000006517 |
| Protein |
| ENSOFVP00000006033.1 |
| UniProt accession | Description |
|---|---|
| Q99MD6 | Thioredoxin reductase 3 OS=Mus musculus OX=10090 GN=Txnrd3 PE=1 SV=3 |
| Q16881 | Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TXNRD1 PE=1 SV=3 |
| Q86VQ6 | Thioredoxin reductase 3 OS=Homo sapiens OX=9606 GN=TXNRD3 PE=1 SV=4 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001656 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02852 all species → | Pyr_redox_dim | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain | Domain | Interproscan |
| PF07992 all species → | Pyr_redox_2 | Pyridine nucleotide-disulphide oxidoreductase | Domain | Interproscan |
| PF00462 all species → | Glutaredoxin | Glutaredoxin | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006338 all species → | Family | Thioredoxin/glutathione reductase selenoprotein | Interproscan |
| IPR036188 all species → | Homologous_superfamily | FAD/NAD(P)-binding domain superfamily | Interproscan |
| IPR004099 all species → | Domain | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain | Interproscan |
| IPR016156 all species → | Homologous_superfamily | FAD/NAD-linked reductase, dimerisation domain superfamily | Interproscan |
| IPR023753 all species → | Domain | FAD/NAD(P)-binding domain | Interproscan |
| IPR036249 all species → | Homologous_superfamily | Thioredoxin-like superfamily | Interproscan |
| IPR011899 all species → | Domain | Glutaredoxin, eukaryotic/virial | Interproscan |
| IPR046952 all species → | Family | Glutathione reductase/thioredoxin reductase-like | Interproscan |
| IPR002109 all species → | Domain | Glutaredoxin | Interproscan |
| IPR011767 all species → | Active_site | Glutaredoxin active site | Interproscan |
| IPR012999 all species → | Active_site | Pyridine nucleotide-disulphide oxidoreductase, class I, active site | Interproscan |
| IPR001100 all species → | Family | Pyridine nucleotide-disulphide oxidoreductase, class I | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR42737 all species → | GLUTATHIONE REDUCTASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004791 all species → | Molecular Function | thioredoxin-disulfide reductase (NADPH) activity | Interproscan |
| GO:0016491 all species → | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0050660 all species → | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| GO:0004362 all species → | Molecular Function | glutathione-disulfide reductase (NADPH) activity | Interproscan |
| GO:0005739 all species → | Cellular Component | mitochondrion | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0006749 all species → | Biological Process | glutathione metabolic process | Interproscan |
| GO:0034599 all species → | Biological Process | cellular response to oxidative stress | Interproscan |
| GO:0045454 all species → | Biological Process | cell redox homeostasis | Interproscan |
| GO:0016668 all species → | Molecular Function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K22182 | TXNRD; thioredoxin reductase (NADPH) | EC:1.8.1.9 | Hepatocellular carcinoma | ko05225 | deepkoala |
