Genomic Location: :...
NR annotation: XP_020614550.1, double-strand break repair protein MRE11-like isoform X1 [Orbicella faveolata]
| CDS | |||||
| ENSOFVT00000009967 | |||||
| Transcript |
| ENSOFVT00000009967 |
| Protein |
| ENSOFVP00000009261.1 |
| Uniprot term | Description |
|---|---|
| Q60HE6 | Double-strand break repair protein MRE11 OS=Macaca fascicularis OX=9541 GN=MRE11 PE=2 SV=1 |
| P49959 | Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 |
| Q9JIM0 | Double-strand break repair protein MRE11 OS=Rattus norvegicus OX=10116 GN=Mre11 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00149 | Metallophos | Calcineurin-like phosphoesterase | Domain | Interproscan |
| PF04152 | Mre11_DNA_bind | Mre11 DNA-binding presumed domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004843 | Domain | Calcineurin-like phosphoesterase domain, ApaH type | Interproscan |
| IPR038487 | Homologous_superfamily | Mre11, capping domain | Interproscan |
| IPR007281 | Domain | Mre11, DNA-binding | Interproscan |
| IPR029052 | Homologous_superfamily | Metallo-dependent phosphatase-like | Interproscan |
| IPR003701 | Family | DNA double-strand break repair protein Mre11 | Interproscan |
| IPR041796 | Domain | Mre11 nuclease, N-terminal metallophosphatase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10139 | DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0016787 | Molecular Function | hydrolase activity | Interproscan |
| GO:0004519 | Molecular Function | endonuclease activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006302 | Biological Process | double-strand break repair | Interproscan |
| GO:0030145 | Molecular Function | manganese ion binding | Interproscan |
| GO:0000014 | Molecular Function | single-stranded DNA endodeoxyribonuclease activity | Interproscan |
| GO:0000723 | Biological Process | telomere maintenance | Interproscan |
| GO:0000724 | Biological Process | double-strand break repair via homologous recombination | Interproscan |
| GO:0006303 | Biological Process | double-strand break repair via nonhomologous end joining | Interproscan |
| GO:0007095 | Biological Process | mitotic G2 DNA damage checkpoint signaling | Interproscan |
| GO:0030870 | Cellular Component | Mre11 complex | Interproscan |
| GO:0031573 | Biological Process | mitotic intra-S DNA damage checkpoint signaling | Interproscan |
| GO:0035861 | Cellular Component | site of double-strand break | Interproscan |
| GO:0042138 | Biological Process | meiotic DNA double-strand break formation | Interproscan |
| GO:0097552 | Biological Process | mitochondrial double-strand break repair via homologous recombination | Interproscan |
| GO:0004520 | Molecular Function | DNA endonuclease activity | Interproscan |
| GO:0008296 | Molecular Function | 3'-5'-DNA exonuclease activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K10865 | MRE11; double-strand break repair protein MRE11 | - | DNA repair and recombination proteins | ko03400 | deepkoala |