Gene detail

Detailed information of ENSOFVP00000009671.1 in Cyphastrea salae

Genomic Location: chr12:10348579...10363997
NR annotation: XP_020624868.1, zinc finger FYVE domain-containing protein 9-like isoform X1 [Orbicella faveolata]
Species Cyphastrea salae · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSOFVT00000010377

ATGGCCAGTGCATTTGTTCCAGTGGATTTAGACAAGCTGTTAgatgaatttgaagaaaaagaacaagAGCCCAAGTCAGAACAGCCAGCTGCTTTTGTTGCCTCTGCTGCAGACAGAAAGCAGGCAGCAAGATTGAGCTTTCAAGCATCATTCCCCAGTATCCAGGAAGAGGTATTATCTGATCAGGGATCTGATCAAAGTGCACTAGATGTCAAGAACGATAGTGACAGTGACAGCAGTAGTATAAATGGAGTGATACAAGCTGCTGAAGCAATTACAAACCAAAGTGCAGAACATCTTGTTGACAACCAAACTGTGGAAAGTTTTGTTGACAAGAATGCTATTAATGAACTCAAAGAGAATGGCGTGAATGAGCCAGTTAGTTATGAGCAATTTGATCTGGATGATGAAGAACAGTTAAACCATGATATTGGTGTTCTCATTAATGAAGAACCCAATGTGGTGACTTTGCAGTCTGAGGAGAATGCATTTGACAGCCAGGAGGCTAACAGTAATGAAATTGATAGTGCAGAAGAGCAGATCTGTAGGACAACTGAGGAGGTTTCTTCATATTCCACACTAGTTTCAAACAGTACTACAGATCAAGAAACACATTTTGTGAGCagggaagaaaatgaaaactactTAGAACGTTCAAGACTAGATGAAATTCGCCAGAATGAAACTCCTGCATTAGTTGATTCAACTTCAGAGGCGGAAGAGACTCCTGAACAAGCTGTGATTAGCAACAGGTCTCAGTATCAAGACACTAGCATTGATGGCTATGAGGTAAATTCAACACTGCAAGACCAGTCGCACACTATTAGTTTTGACCAACCTGGATCATCCAGTGTTCTTACGGCTGGAGATGGTGAAACTAATTATTCAGGGCTTAAAGAAGCCCCTAACGAAGAAGCGCAAGAATCCTATGAACAGAATGAACCTGAAGGTCATCTTGTTTTTGTGGAAGACGAATCCAGTTTTAGAGACCCCGAAAATGGTGTAGAACAAGGTAGCTTTAATACAGATAATGAACAGCCCTCAACTGGATCAGAGGAACGTACACAGTCACCTGTTTTGACCATGACAATGCAGTCTCATGGGACATTATTAGAAGCTCGGCGGATTAGTTCAGGAGAATCATGCCTCGGTAAAGTGCCACCCATTTGGGTTCCAGACTCTGTAGCTACGCACTGTATGAACTGTGGGGTGAAGTTTAGTGTTATTAAGAGACGACATCACTGCAGAGCTTGCGGAAAGGCCCTTTGTTCATCCTGCTGTAACATGAAGTTCTTGTTACCATACATGGACAACAAGGAAGGCCGTGTTTGCCAAGTTTGCTGTAATGCCCTGTTGAGAGCCCAGACATTATTGGAAGTGGCAGAAAACCAAGATAATGTCCACATTGCAAGTGATTTTGACAGTCTGCCACGCGACTCGCATGATTTACTCTTAGAAGATGTTTTGGAGGAAGATGAAGAGTTGCTAGATGACCAGCAAGAAATTGGAGCAGGTGCAGAGGCTATTGGAGATGATACGACAGATTTGGACTTGTCTGCAACAGGTATGGGCGTCACAATGGAACAGACACCACCAATTCTTCCTCCATTACAAATCCCTGTAGCTCCAGTCGCAGACATGATAGGGACACCATTATCCACCCCAGCATCACCAGCTCTCTCAGATGACAGTGATTGTCTGTTTCGATTAGATGTTGATAATGTGCGATCTTTGTTACCTGAAGACGTCACTGCACTCCCTCCAGTATTGAAAGTTGTAAATGAAGAGATATCTATTCAGGAGAGGCCTGATCCTGCAGAAATTATGTATCAGATAAAAGGTCTCCATGAAACTGTTGTATTTTTACTCAATAAAAACTTGGTAGTCAAAGTCAGCATAGTGAAATTAAACTGTTGTGTAAAACGGAAGTGCTGGTGTTTTGTGACAGAAGGAATGGGAGCTGCAAACCAAGAGGAAATGGTGGTTTTGTTAGAGTGTCTTCGTAAAGAGGCAATGCTTCCCAAAGATGTCCTCTCACACTTCAACACAGCTTTTGCATATGCCAAGCAAGGTCACACAGTGTCAGAACTTGGTTACACTATTTTTGGTCAGCCCTTTCTTGGCAGTGGTGACAATGCAGGTTTCCTTTATGTGAAGCCATCATTTCAGTGTCTCAAGAACATCCCTGTGCCATCAACACCTTATGTGGTAGGGTTGCTGATAAAACGTCTGGAGACACCTTGGGCTCAGCTGTTTCCCTTGAGACTTCAGCTAAGACTTGGGGCTGAGTTCAGATATTACCCCTGTCCGCTGTTCAGTTCGAGGAACAGATCATCAGTGTATGGAGAGGTTGGACACACAATCATGAACCTGCTAGCGGTAGTGAAGATTCTCAATGCGACAGATGAACATGTTATGGCTCTGGGAGCGAACTTCAGTTTACAGGCAGACTCACACTTGGTCTGTATGCAGAATGAACAGGGCTACAAAACTCAAGCAATTAACATACAGAATCAAGCCAGGAAAGtGACTGGAGCAAGCTTTATTGTATTCAGTGGAGCACTGAAGCCCAGCAGTCCATTCATGGCCAAAGTCAACATTGTAGAAGATGGTATCATGGTACAGTTAATGCCAGAAGTGATTGATAAGTTACGGCATGCTTTGAAGGAGATGCAGGACTATACCATTACCACAGGGATCCCAGGTCAGGGAGGTGAAGAGCTGGTCATTGTAGAGTGGGTCAGTCGTCAAAACAACCCACAAGAAGACAGTTTGTGCAGTCCAGTGGATGGCCTACGGCTTGACTCTTTTCCCAGTGTGAAGGTTCACAGTGGCTGTGACTTTACTCGCAAGAATTTATTCAGAATACAGTGGACAGAGGTTTTCTTCCTAGGTGAAGGCCAACAAAGTGCATCGCGGGATCTCAATAAACTGACTGCAGAGCTTGCCAAAGCATTTTGTCAAACACTTATGCCACACTTGTCCAAACTTAGTTCAGACGGCTTCAGCTTCATTGGGTTGAGAGTGAATTTGGATCCTGATAGTGTTGGCTATTTTACAGGGAGTAACCAACAGAGCTTACCTGCCAGCATCATGTCAGATCTCGATGATGTCTTAGTCCCTATCATTCACTCTGCAGCAAATAACCAGAGAGTCCGTTCTCTTAGTATAGAATTGTTGTTCAAAGTTTTGAGGCTTCTTTGA

Transcript

ENSOFVT00000010377

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O95405	Zinc finger FYVE domain-containing protein 9 OS=Homo sapiens OX=9606 GN=ZFYVE9 PE=1 SV=2
Q7Z3T8	Zinc finger FYVE domain-containing protein 16 OS=Homo sapiens OX=9606 GN=ZFYVE16 PE=1 SV=3
Q80U44	Zinc finger FYVE domain-containing protein 16 OS=Mus musculus OX=10090 GN=Zfyve16 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004643 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF11979 all species →	SARA_C	Smad anchor for receptor activation-like, C-terminal	Domain	Interproscan
PF01363 all species →	FYVE	FYVE zinc finger	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR022557 all species →	Domain	Smad anchor for receptor activation-like, C-terminal	Interproscan
IPR017455 all species →	Domain	Zinc finger, FYVE-related	Interproscan
IPR000306 all species →	Domain	FYVE zinc finger	Interproscan
IPR006058 all species →	Binding_site	2Fe-2S ferredoxin, iron-sulphur binding site	Interproscan
IPR011011 all species →	Homologous_superfamily	Zinc finger, FYVE/PHD-type	Interproscan
IPR013083 all species →	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46319 all species →	ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0046872 all species →	Molecular Function	metal ion binding	Interproscan
GO:0016197 all species →	Biological Process	endosomal transport	Interproscan
GO:0031901 all species →	Cellular Component	early endosome membrane	Interproscan
GO:0051537 all species →	Molecular Function	2 iron, 2 sulfur cluster binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04679	MADHIP, SARA; MAD, mothers against decapentaplegic interacting protein	-	Protein phosphatases and associated proteins	ko01009	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Cyphastrea salae tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Cyphastrea salae, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →