Gene detail

Detailed information of ENSOFVP00000021102.1 in Cyphastrea salae

Genomic Location: not available for this species
NR annotation: XP_020620969.1, breast cancer type 1 susceptibility protein homolog [Orbicella faveolata]
Species abbreviation CSALA · all data for this species · gene families

Sequence

CDS

ENSOFVT00000022712

ATGTCTGTGAAGGTTAAAGATGTCTTGGACGCCCTTCAACAGATGCAAAAGAGTCTTGAGTGTTCGATATGCCTTGAATTGTTGAAGGACCCTCACTCAACAAGATGTAATCACCAGTTTTGTGGTCAGTGCATCAGGCAAGTTCTTGAAAAGAGCAGCAAGAAGTCAAAGAACAAATGGTATTGTCCACTCTGCAAGACCCCTGTCTCCAAACGGAGTCTGACGCCAAATcctaaattaaatgaaattgttgCTGCAGTGCGCAATTTGCAGGGAGCAGTGCAAGAAGATACTGGAATTCCAACAGGTTCTCCACCTTCGCAGCAGTACAAATTATCCAACACGGCAGGTACTTCAACATGTGTTACATGTGATTCTGCTACCCACCATCCAACCCCTCAAACACACCAAAATGACTGCAAGGGAATTAAGAGGAAAGTCACAAAGAAGAACCAATTTAATGTATACAATGACAATGATGGTATTTCAACATTAGGACCACGACTAACGCAAACTACAGCAAACATTACAAAATCTAAGAAAGCATCAAACACAAAATCCACAAGACGGACAAGGAACTCTAGAAGAATAGCTCAAAAAAGTCACGCTGAGGAAACACTAAACGGAAGGAATGTCAGTGAAGAGCTACTTCATATGATCGACACCATGCCATTCCAGCCAGTTTCTAAAGGAGGTAAGTTCACATCACGCGCAACGTGTGGGAAGATGAGAACAGAACTCACTTTCAAACAGTTATATGAAACTGTAAGGACAGGAGATAGTCGACAAGCAATAACAGGTAGTAACGAGACGTGTCAGAGTGCCCCGGTAAATCCTGAAAAAAACACACGTTTAACAACTATCGCTGAGGCGGACTCCTCTGTCAGGACAAGCCCTTGTGACAGTGTAGCATTTTGTAGAAACAAGGATAATTCACAGCCCTATGTAGTTACAACGACGCACGACAAGGAAGATGAAAGAGCGGTGTCGAGCACAAAGTTTGACTCTTGTCCAGTGAGTAGCTTGGACACCATGCAAAGTGTGTCTATACTTGCTTCCCTGGATTACGAGGCAGCTCCTGATAATAATTTCGAAGTCCGACAGGAAGGTGCTCGAAAGGATGAAGGTGCCTCCAGTAAAGACATAGATGAGGTGTCAACCAAGATTAGCGATGCAGGAAAAGAGAAGGAGGCATTTGTTGTTTGCCAAGGACAACAGACCAATCATTATCAACAATCGTCTCAAACTATAAAGGAAAAGTTGCCCTCTGAAATTATTGCGGGCAGTGTCAAGGATCATGAAACTCAAAGCTTAAGCCTTGAAGAGTTGATTTCCTTATTTGATGAACGCTCTTTGAGTAAACCTTTAGAGGCATCACCAAAAGCAGTTGAAACTGAGAACGTCCTTCCAGATTTGAGTAAAATCGGAAAGAAAGCAGTGTCCCCCAGAGAGAAAAAGCAAGGTCACCAGGATGCACTTGTGCTTAAAAGCACCGAGTCTGACTTGTACGAACGTGTTAAGCAAAGGCAAAGGAGACGGCCATCTGAGATGTCGCTGCAATCCAACCGACATTCCGACCCTCCAAATTTGAAAACTAACCAGCTGAAGATGAAGACAAGGAAGAGATCGGCGGATACTGTTGCTGTGTCTTCTCGAACTGACTCCATCTACGATGGAAATGccagaaaaaagttaaaaaaatctgAGGGTCCTGCACTCCATCAAGATTCTCCGCTTAAGGTGAATGTGGAAAGTTCACAAGATGTAGATGGACTTTTTATTGAGTGTAAAGAGGAGAGAGACGAACATGTGAATGGATCAAAATTCCACTCTGTGAAAGCTAATGACCGAGATGGTGCATTGAGCCTTAGAAGTCAATCGCGTTCAAGTGACAACACTGTGCCTTCAAATGAAATGGTTCCAGCCAGCGTCTCCTCTTCGGAGAAATCGATCCCTTTAGCGATCAATCCAATGATTGCTCATGTTGATCAGGCTTCAGATGACCCACCGAGAGGTTCTACAGAGAACACCAATGAATGGGGTTCGCAGAAGAGAAGAGAAAGTAACCACGGAGAAATAACTAAAAATCGTATCTTTATCGAAGATGGCTTACAAAAGTTTGTAACAAATGAGCAAAGCCCCCAAATAAAGCAAATTCAGGTTGAACGAAAGCAGTTGAAAGACGAACCTGAAGACAAGGAACAAGCCTCTCAAGACGCAGAGTTCACGAACTTCGGAATTTCCAGTCCAATACAGCAACTATTTTCAATGGCTCTACAGGTGGACGGTTCCGAAAAAAATGATTCAGTACCAaagcaaaagcaatttacaagtTCTTTCAACAGGCATTCTCAGGAGGAAACAGGAACAAGTGGCAGTGAAATCGAAGGCAAAATGTGTAATGTAACTGTTGAAGCTGGGGGAAAAACATCTGGGCCGTCGAGTGTGGACTTTTCAGACAACACTCCAACTCAAAGTTCCTTGGACGTCATGGATGCAGTGACGCCTTGTCTGTTTGAAAACGATAGCTGGGAGACTCCAAACAGGAAAACGAGTCCGAAGAAATCTGAAAACAAAAGGGGACCTAAGATCGCGTCCGACATCTGTGGGAGAAATTATAAAATGGCGTCCAGATGTTCCCAAACTCTTGGTCTCAGTTGTCAAACTGTAACTGAAGAGGAGAAGATTGTGGAAAAAGTTGGTTTTGAAGGAATAAATTCATTGGATGGTAGCCCAGTTGAAGCCAAAAATGTTGAACAACAACAGTTCTCTGGTGTGGCTCGCTGCTCTGATGGTAGTATCAAAGAGCTGGCGTCGGACGCAGAAGGCACTCAGAGCTACGGGACCAGTCAGAGTATCTCTGTTCTTCAAGATTTGGAGTTTCCACTGCCAGAACTCCAAAAGGACGCGGATGCTGCCTTCAGTGAACAAAGAGACGAAAGAGAGAAGTCCTCGCAGAATGTCCACGAGGAGTCAAAAGGAGATGCTCCTTGGGCAGAACCTCTTCCAAAGAAACTAAGAAGTGGCGAACCGTTATCAACGTCGTGCAATTTAAATCTACTAAACGTTACACTTGACCGGGGGATTGGTTCCAGCATCGAAATGACCCGCGACTCACAGTATACGGAAAGTGACGTCATACCACCCACACCACCGGTCAAACCTGTTGCTAAACAGGTTTTCAGTTCTCGCAGTCCTATAAAGTTATCAAGCCCCAAAATGAAACCACAAAGGAAAGACGAGGCAACCTGTCATTCAGAACGTCTGGTTGTAAAACAGAAGAGGCTAGTGGAGAGTACTCGTCTGTCAAAGGCAGTGAAATCACATGATAGCGAAGTAGACAGAGCTGGAGCACGTTGTAATGCCACATACAGTGAAGACAGCGTCTCGTTGCTAAAAAAGCACGAAAAGATTTCAAAGGCGCCAAATGCTCATACCATAGACTCAATCAGTAAAGAGCAGAAACGAAACGGCGCTTCGTCTGAAATGAATGATTCTAACAGTGTACAAGACAAAGATGATATTCAAGTTTcacaaaaagaaagacaaagggTCTTGGCACATTTTGAAGTGGAAAAGCGCACGGACTCAGTGAATAGACCTTTGGGTGAAATACAAGATGAAAGTGTTAATTCCTCACCTCGCAATCCTGTGAAAGGGAGAGTTTTTGATATTGCAGATTCGTTTGATTGGTCGGGTACTAAAGACAAGGGTGAAGGCGAGAGAAACTCGCAAGATGGCTCTGTGATTCTCATTGTCGACGATAATAAAGACACCGAACGTgtcaaagaaaatgaaaagaaagatgaaaatGAAGCTTTGACAGATGGTTTCCCAAAGTCCGTAGCAGGACTCTTCCAAAGGAATGATGATCGTGACCGCATCCTTGTTGATGTTCAAATTGGAGATTTCCGTGATAGAGACGAGGATGTTAATTCCCCTTGCACTTACGATGGAGGGGAATCCTCGAGCGATGAAGCTCTGTTAAAGCCGGTGTTCCTTCCGAAGGAATTTGAGTCAGGTACCAATGCAACGACCTACGAGGGAGGTGCAGAAAATGACGAGGAGCAAGAGACAGCATTTTCTCAAGAACTAATTCCTTCTGAAAATGAGGATGAAGACGATGACGATGGAATCACATCGTCATATAAAGCACTGGACAGCACTGGTGCCTCGTCTGCTACATTTCTATCTGAAGCTGCAGCCTCTACTCAGAAAATGGAAGTCCTACGACAGGACGTGGAAGAGATTGAAAAGGAGATGGAGGAGTTGAGAGCGTATCTTGCTAAAACCGACGAGAAACGAGAGGAAGCAGAAACCACTATTGAAGATGATCCATGTGATGATGACCCGGACATTTTACCTTCACTCACTCCACCTCCTCCATTAACACCCAAGAGCATCCCACCCATGCGACAACTTTCTTCCCCCCTGAAAAACGTTTCACGCTATCTAGATCAGGAGGGACAGTCTTCAGATGAAGACAGCGATTGCGAAAACCTGGCGAAGACTAATGAAGAGGAACAGTGCGAGCAAAGGAAAAACACGAGAATCGAAGGAATCAGGAGTGTCGGAGAGATGGAGGATGCTAACAAAACATGTACAAGAAAACGCCCTCTTTCTCCGAGTAATGAAGATGATAGCTTAACTATAACAGCGGTGAAAAACCGACAAGCAGAAACTCCTTCTCCACCGCCCAGTGGTCgttcaaaacaaaattctcAGGATAAAGACGAAAACGAGTTGATTGTGATTGACGATCGAGACTCTGTTTACTCGAAAACTGGTTCTCTTTTGCTTGTTAAGAGGCGAAAAGTGACAGACGAATTCGTCCCCAAGAAATCTCCGGTCGTTAGTTTGTTATTCACGAGAACACGAAAAGAGCTCGCTAAAGCTAACCCTGAGTCCCCAAGGCAAGTCGAGCAGACTAAAGCACCGTCACCTAATAAGAAAAAGTCGTCACCTTTTATCTATTCACGAAAACGAAGTGCGGAGATCTCGCCGATAAAGGGGAAGGAGCCTCCACGGGTAAAATCACGTGATAATGCGTCACGTAACATAATGTCACGTGAAAGTGTGTCACGCGATGATGTGTCACGTGATGAATTTCGTTCATCGGATCAGGAGTGTAGAAAGTTTAAGGTTGTGACGAATGCAACAACGAGCTTGGAAAAAGAGGATAATAACTGCGGGGGAACTGAAACAAAGCACCTGTCTTTTGTGGCGACGCGTCTTAACAGGAAGCAGCTAGCCGAAGCTCGAGCCCTTGCCGAAACGTATGGCGGAAAACTAGCCAGTGAATTCAACAGCAAGACGAGCCACGTGATTATGGCAACAGATGAGAACATGCAGGTGACGCGTCAAAGTTATACCATGAAGTACCTATTGGGACTAGCCCTTGGCAAATGGATTGTCAAGGACGAAACTTTCTTTCAGTTGGAATATGAAGTGAAAGGCGATCCAGGTCTCGGACAGGCCTCCATCCCTCGCGTGGCAAGAACAGCCAGAAGTAGCAAGGAGGCACTTTTATTCGAAGATGTTGATGTTGTCTGTTTTGGCGAATTCAGCGCCGCGGTCACTAAAGATCAACTTAGCCAGTTGTTAAAGTTCTGTGGTGCAAGTGTCTACATCGATGCTGAAAGTTTAAAAAGAATGGATAAGAATCGCCGAAAGGTTGTCGTCATCGATAAAGAAACTCGAAACACTACCTGCCGCCAGTTGAACACAATGCCTGTTTCTTTGGAGTGGGTCACGGATAGCATTcgtcataataacaaagcggcacgcaagataatattcggaaatgtaaaccgccttcgcttcattcaaatcctagcttctaaacggctaaaataa

Transcript

ENSOFVT00000022712

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6J6I9	Breast cancer type 1 susceptibility protein homolog OS=Macaca mulatta OX=9544 GN=BRCA1 PE=3 SV=1
Q6J6J0	Breast cancer type 1 susceptibility protein homolog OS=Pongo pygmaeus OX=9600 GN=BRCA1 PE=3 SV=1
P48754	Breast cancer type 1 susceptibility protein homolog OS=Mus musculus OX=10090 GN=Brca1 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005091 (this species only)
Ubiquitin family	E3\|E3 activity RING\|RING · all ubiquitin genes in this species
Ubiquitin family	E3\|E3 activity RING\|U-box · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00533 all species →	BRCT	BRCA1 C Terminus (BRCT) domain	Family	Interproscan
PF00097 all species →	zf-C3HC4	Zinc finger, C3HC4 type (RING finger)	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001357 all species →	Domain	BRCT domain	Interproscan
IPR036420 all species →	Homologous_superfamily	BRCT domain superfamily	Interproscan
IPR001841 all species →	Domain	Zinc finger, RING-type	Interproscan
IPR031099 all species →	Family	BRCA1-associated	Interproscan
IPR013083 all species →	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	Interproscan
IPR017907 all species →	Conserved_site	Zinc finger, RING-type, conserved site	Interproscan
IPR018957 all species →	Domain	Zinc finger, C3HC4 RING-type	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13763 all species →	BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000724 all species →	Biological Process	double-strand break repair via homologous recombination	Interproscan
GO:0004842 all species →	Molecular Function	ubiquitin-protein transferase activity	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006281 all species →	Biological Process	DNA repair	Interproscan
GO:0006974 all species →	Biological Process	DNA damage response	Interproscan
GO:0031436 all species →	Cellular Component	BRCA1-BARD1 complex	Interproscan
GO:0035066 all species →	Biological Process	obsolete positive regulation of histone acetylation	Interproscan
GO:0035067 all species →	Biological Process	obsolete negative regulation of histone acetylation	Interproscan
GO:0045717 all species →	Biological Process	negative regulation of fatty acid biosynthetic process	Interproscan
GO:0045944 all species →	Biological Process	positive regulation of transcription by RNA polymerase II	Interproscan
GO:0070531 all species →	Cellular Component	BRCA1-A complex	Interproscan
GO:0046872 all species →	Molecular Function	metal ion binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10605	BRCA1; breast cancer type 1 susceptibility protein	EC:2.3.2.27	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.