Gene detail

Detailed information of ENSOFVP00000027424.1 in Cyphastrea salae

Genomic Location: chr6:12029477...12041963
NR annotation: CAH3030233.1, unnamed protein product [Porites evermanni]
Species Cyphastrea salae · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A0MTA1	DNA repair nuclease APEX1 OS=Danio rerio OX=7955 GN=apex1 PE=1 SV=1
P43138	DNA repair nuclease/redox regulator APEX1 OS=Rattus norvegicus OX=10116 GN=Apex1 PE=1 SV=2
P27695	DNA repair nuclease/redox regulator APEX1 OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003223 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03372 all species →	Exo_endo_phos	Endonuclease/Exonuclease/phosphatase family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR004808 all species →	Family	AP endonuclease 1	Interproscan
IPR020847 all species →	Binding_site	AP endonuclease 1, binding site	Interproscan
IPR020848 all species →	Conserved_site	AP endonuclease 1, conserved site	Interproscan
IPR005819 all species →	Family	Linker histone H1/H5	Interproscan
IPR036691 all species →	Homologous_superfamily	Endonuclease/exonuclease/phosphatase superfamily	Interproscan
IPR005135 all species →	Domain	Endonuclease/exonuclease/phosphatase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22748 all species →	AP ENDONUCLEASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003906 all species →	Molecular Function	DNA-(apurinic or apyrimidinic site) endonuclease activity	Interproscan
GO:0004518 all species →	Molecular Function	nuclease activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006281 all species →	Biological Process	DNA repair	Interproscan
GO:0006284 all species →	Biological Process	base-excision repair	Interproscan
GO:0008081 all species →	Molecular Function	phosphoric diester hydrolase activity	Interproscan
GO:0008311 all species →	Molecular Function	double-stranded DNA 3'-5' DNA exonuclease activity	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0004519 all species →	Molecular Function	endonuclease activity	Interproscan
GO:0000786 all species →	Cellular Component	nucleosome	Interproscan
GO:0006334 all species →	Biological Process	nucleosome assembly	Interproscan
GO:0030527 all species →	Molecular Function	structural constituent of chromatin	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10771	APEX1; AP endonuclease 1	EC:3.1.11.2	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.