Genomic Location: chr6:2443167...2451095
NR annotation: XP_020622857.1, membrane-bound transcription factor site-2 protease-like isoform X2 [Orbicella faveolata]
Species Cyphastrea salae · all data for this species · gene families
| CDS |
| ENSOFVT00000029721 |
| Transcript |
| ENSOFVT00000029721 |
| Protein |
| ENSOFVP00000027611.1 |
| UniProt accession | Description |
|---|---|
| Q8CHX6 | Membrane-bound transcription factor site-2 protease OS=Mus musculus OX=10090 GN=Mbtps2 PE=2 SV=1 |
| O43462 | Membrane-bound transcription factor site-2 protease OS=Homo sapiens OX=9606 GN=MBTPS2 PE=1 SV=1 |
| Q5RAC8 | Membrane-bound transcription factor site-2 protease OS=Pongo abelii OX=9601 GN=MBTPS2 PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0007031 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02163 all species → | Peptidase_M50 | Peptidase family M50 | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001193 all species → | Family | Membrane-bound transcription factor site-2 protease | Interproscan |
| IPR008915 all species → | Domain | Peptidase M50 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13325 all species → | PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004222 all species → | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0006508 all species → | Biological Process | proteolysis | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0031293 all species → | Biological Process | membrane protein intracellular domain proteolysis | Interproscan |
| GO:0051091 all species → | Biological Process | positive regulation of DNA-binding transcription factor activity | Interproscan |
| GO:1905897 all species → | Biological Process | regulation of response to endoplasmic reticulum stress | Interproscan |
| GO:1990440 all species → | Biological Process | obsolete positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K07765 | MBTPS2; S2P endopeptidase | EC:3.4.24.85 | Peptidases and inhibitors | ko01002 | deepkoala |
Genes whose expression across the transcriptome samples of Cyphastrea salae tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Cyphastrea salae, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
