Gene detail

Detailed information of ENSOJPP00000010287.1 in Anthopleura xanthogrammica

Genomic Location: chr13:5550549...5571521
NR annotation: XP_031562662.1, rho GTPase-activating protein 5-like isoform X1 [Actinia tenebrosa]
Species Anthopleura xanthogrammica · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSOJPT00000011914

ATGTCCAAGAAGGCTAACGAAGCAAGAACATACAACATTTCAGTTGTAGGACTGTCTGGTTTGGATAAAGACCAGAGTTTGTACGGTGTTGGCAAGTCTTGTCTTTGCAATCGTTTTGTGAGGCCGTTAGCCGATGACTTCATCACAGATCACACTTCAGTCTTCAGTACGTCGGATTTTGGTGGTAGAGTCATTAATAATGACTCCTTCTTGTACTGGGGTACTACTACGAAGGTAGCAGAGGACGGAACCGAGTATAAATTTAATGTTATTGAGCAAACGGAGTTGATAGACGATGCTTCTCTTATGCCGCTCACTCGTGGTGTGCCCTACCCTAAACGAGCCACTACTACTAAGCTCAGCTCACCAGAAAAACTCATGTACATCAGTAGAGAGCAAGTGGCACTTCAGACCGATTACCCACAAGTTCTTTTTCCCACTGGGAAGCTAACTATTGATGGATTTTTGGTAGTTTACGACGTAGAGTCAACTAACGCCAAGCGACTCGAGGAAGCTCAAGAACGCTTTCTCTCTACGCTTCTCTCTCTCGTCCAAAAAACTAAGAAACCTTTCGTGATTGTGGCCAATAAATGCGATGATACACAGCTAACTCTCTTACAAGAAGTTTATAGATTCATTCAGTCTAAAAAGATCAATTCTCCCATAGTTGAATGCTCGTCTCGCGAAGATGTGAATGTTGACTTGGGTTTCGTCGTGCTTGCTCAGCTAATCGATAAGGGAAAAGTCCGCTCCAAGTTAATCCCGTACTCAGAAGCTCACAAAATACACCAAGAAATGATGGAAAAAACCTTACAGGAATACCAAGCACTGATCAACAGAACTGTATCGGACTTTAAGTGTCTCTGGAAGAACGTGAAACGGCAAATCGAAGGGGAAAATGAGTACCAAACCTACAAAGACAACTATGGGTCTGAgagttgtaaaaaaatatttaccaaacACATACGAAAGCTTCGACGAgagtttgaagaaagaaagctcATGGAATATTTATTAAAGCTTCCACATGCTCTAGATGATCTTGTACCTACTATAAGTTCCCTAGAATTGTGTCATTATAGCTGGGACATTTGTCAAAAGTTGATCCGGAATCACAAGGACTTTAGCAAATGGATGGTCAAGTCGGAAGAGAACACGGCATGGAACGAAAGTGAACACTTACAAAGTGAGGATCTTAGGATTCCATATGATGTCTTATCGTTACCCCAGGCAAAACAAGCCTTCCAGATTCATATCGACAAACTAAGGGAAGCTGAGAAGAGAGTCAGGATGAAGAATGAGTTTCGGAAACTTTTGGAGCTGACACCACAGATTCGACCCGGGAGTGAATGGGATGAGATCGAAGGCATCTTGCAAAACGAAGAGAGTTATAAATACTTGACCGAAAGCGATCGAAAGGAAATATTTAATTCATACCTAAGGGATATTGCCGAGAAGGCCAAGGCTGACTTCCAAGAATTACTATTTGAATCAGCTAGCTGTTTTACCAAGCTAGAACCTACCCCCTCTGAGGATGACATGAAGGCGATCTATGCTAGCTTATGTCTGGATGACAGATATAGGCGGCTAGATAAACTGGAAAACGATAGGAAAATAAGGATTCTGAACCACATTGCTCTACTAAACAGCAGTTCAAGATGCCTGTGTGGACCCGAAAAATGTAGTGATCGACTGATGCAAGAAATAGTAGCTACAACAGCTCACAGACCAGAGTACTCTGGGAGTGATGAGACTCTTGACAGTGAAGACAGCCAGCTCAGTATTGTTGTGTTGGGCAGTGATGGACTGGCAGATGCCCTCTCCCAGGAAATTCagGCACAGTGTTCTTATGGTGGAGAAGGGCTAGAGTTTGTCCTTGATGGACGCATGTATGAGTTAGATTTGAGGGTGGTGGATGGAGATATGGACCTACCAGAATATGCAATTACTAATACAGACAATCCACCTCATGGTTATTTTTGTGTCTATTCCACCCTGTATTCTCTGGAATATATCCAAGAGGTGTTGGAAAACACGTACTGTAAGCCAGGGTACAACAGTGTTGACGACACCAACATGCTTAACCTCGCAGCATCTATCACTATCTTCCTTGCCAAGAACcatgataatgaagatgtTTTGACCACCTTGAGGCAGAAGGGACAATATTTGGCAGACAGGTTTGGAGCGTCATTTATTGATATCCCTCTAGCAAGGTTTTCCCGTGATAAGATGATTCATGAGACCCAAGTAGTTGACGCCATGCGTATTCTGGTTGAGGAAATCAAACAACAAGCAAGAACACTCAATTCAACTGATGATATCAGAGACTCAGAACCTGATCTAAGGATCATGTTGTGTGCAATGTGTGGAGATTCATACCCAGTGGAGCTTATCTTTGGTCCATTACTGCACCATCAATCTTGTTGGCGTAGTCCAACCCAGCCAGATACCATCATACTAGAAACCTATGTTGGCTTTGTTAAAAGAAGAGTCCAAATCAAGCTCACTTCGTATCATCGTGCTTACACGCTCAATGATCAGATGTTCCATGGATACATTCTTGTCTATTcagcaaaaagaaaagcatCTTTGGCTACTCTAAGTGCTTTCTCGTCGTCCATTCCTCACGTCCCTATCCAGGTCTTAGCAGTGACAGGGAGCGCATCGGGTGCCAGTGTGGTGTTCCACAGCAATGATGTCCCTGTGTCCCTTTTAGCTGAGGGGGTCAACCTAGCAAGCAAATTATGTGCCAAATTTCAAACTACGTCAACTACAGTTCAGCATCCAGGTGGACTGTTTGCTGCGTTCTTTAATCGTGTGTGGGAAAAGAAGGGTGATAGTGAGATGGCCTACACTGATTTCATGAACGAACAGCGTGCTCGTCAAGAACATCGGCTTCAGTTAAAGAAGCGCAGCGTTCACGACCCTCTTCCTGCTCCACCAAATGTGCGACTGGCAGGCAGTGACAATGAACTGCGGCGAAGGCGAACAGCTAGCGAGCACCTCCCAGGCTCACCTAAATCATTCCATCGATTATCAGCAAATAATCTTGATGAAACAACACCATATGCAGAGTTCAGCCCTGAACAAAAGGCATTAATCACTGCAAAGTCTGGTTCAGGGGAGCATTTGATCCCAATGACATCAACTCCCAATGCTGCTCTGACCAATAACATGACAAAAGAGGAAAAATCCACAACGCCTTTGAATAATATCTATGCTGTACCTGACAAAACCAGGAAGATATCTTTTAGGAAGTCCAAGGATGCTAGTGCTTTCAATGAAAGTGAGGTCAACTTGATTGAAAACTCTCTGTATGCGAATCCAAACCTCATATCAGGTACTGGAGCAGGATATAGTGAGATTCCTCCTCCCTTACCTGACCGTATGGACAATTATGATGAAGACTACCCACCAAATGACTCTGGCGTTGATACCTTACGTAGTATGCATAACGGTTATTCTACCAACAATTCAGAAGCCAGGAACAACGTTAGATGCACTGAAAATCGAAAGTCGACTGGCAGTAGCTGCGTTTACGAGGAGATCCCCAATACAGATCCTCCTGCTAGTCCGATGGAGAAAGATCCTTACCAATACAACGTAAGAACCAAGATACAAATGTTTGATGAGAAAACCAAACATGATAACACTAAGCAAGACGTATGGGTTAAACGAACCAAGGCAACTGACCATCGTAACTCAGTACCTGACTTGTACAGTAAGGTGAAAAAAGCACCGCTAGCACAACAAGAGGATGACGAAGAGCCTGGGTATGCACGAGTTAAGGATGACTGCTTTGAACTCCACCCTCCAGTCTACGCTACCGTCAAAGACAAACCAGAGGAAAATATGATGGTATTTAACACCGGTACACTACGATCTGCTCACTCTGCAGAGGAATTAGGGTCTGCTACGTTTGAAcgtagaaatagaaataagaaaacagAAATTCCCTTCTTCAATCGTAGCAAACGACGAGAACAGCGCCCTACACTAGATGGTGTGACTTCAGATGGAGGGACTGGTGACGAGGACTCGATGTCACGAAAGCCTGATCattacaacaacaagaagCTTATGTTAAGAGATGAGCCGTCTAAGAGAAAAGCTTCACCTGGACGTAAAAGAGATAGTTACAAAAATACTGAGGCTGTTACTCCGAATGTTTCTGTTGAGATTGACGAGAACCACCATGAAAGgaccaaaaacaaaaagaaagGATCGAAGAAAAACAGACAATCCAAAGGAAAGCCATTTGTAGGAGACTCTAATGAAGAATCATCAGACACAAGTAGCTTGGAGAacaagaggaagaaaaaccgATCCAAACCAACCATCACATCAACCGCTTGGTTTTCTCCTGGAATCAAGGTAATCCCAACTTATATTTGGAGGTTTAGTCAGTCAATAATCGAACCTGAAACTGAAGAAGATTTGGTGTCGCCATCAGCGAGCCTTTCTAGAAAAAATaattcttTGTCTAAAAAGAAGATCAACCAATTGgagaaggaaagaataaaaaaagagaaaagacaaaaacaacagcagaagcaGTGGAACAAGAGGAAGCGCAATGAAACCAATTTTGAGAAGATCAAGAAACGTGAAGAGACCCCAAGCTCTTATTTTGGACGTAATCTGGATGATATATGTGAGCCGGGGAAGACCACACCTTTATTTGTtgaaaaatgtattgaattcATCGAAGTTGAAGGAATACAACTGGAAGGAATCTATCGTAAGAATGGCAACGCCCTCGATGTTCGGTCATTGATGGataaatttgaagaaaATCATAACGTAGACTTTAGTACTCTTAACATGAGTGCGCACTCAGTGACTGGGGCTATCAAGTCATTTTTCAAACGTCTACCGGAACCGCTAATCCCTAATAAACTACAAGAGTCTATCTTAGAGGCAACAGTAATCATGAATGCTAATGAACGCCTCGCTGTGCTCAAGGATCTGATAAACGAGATGCCGCCGCTAAACCTCGCTCTCTTGAAACAGTTCACCTTCCATCTCAGCAGGGTAGCCGAATACTCACACGTAAACCTCATGGAATCCCGGAACCTATCAACGGTCATCTTCCCTACACTTCTGCGAATCGAGTTTGAATCACTCAAATTGATGGCAAGACAGATGAACTTTGGCCTGTTCATACAGACTTGCATCGAAAAGTGTGAATATTTCTTTGGAGAAGACCCCGAGGGTCAGGAGGTTCAGTAA

Transcript

ENSOJPT00000011914

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q13017	Rho GTPase-activating protein 5 OS=Homo sapiens OX=9606 GN=ARHGAP5 PE=1 SV=2
P97393	Rho GTPase-activating protein 5 OS=Mus musculus OX=10090 GN=Arhgap5 PE=1 SV=3
P81128	Rho GTPase-activating protein 35 OS=Rattus norvegicus OX=10116 GN=Arhgap35 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002524 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF16512 all species →	RhoGAP-FF1	p190-A and -B Rho GAPs FF domain	Domain	Interproscan
PF19518 all species →	RhoGAP_pG1_pG2	p190RhoGAP, pG1 and pG2 domains	Domain	Interproscan
PF00071 all species →	Ras	Ras family	Domain	Interproscan
PF00620 all species →	RhoGAP	RhoGAP domain	Domain	Interproscan
PF01846 all species →	FF	FF domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000198 all species →	Domain	Rho GTPase-activating protein domain	Interproscan
IPR002713 all species →	Domain	FF domain	Interproscan
IPR039006 all species →	Domain	Rho GTPase-activating protein, pG2 domain	Interproscan
IPR008936 all species →	Homologous_superfamily	Rho GTPase activation protein	Interproscan
IPR032835 all species →	Domain	Rho GTPase-activating protein, FF domain	Interproscan
IPR036517 all species →	Homologous_superfamily	FF domain superfamily	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR045786 all species →	Domain	Rho GTPase-activating protein, pG1 and pG2 domain	Interproscan
IPR039007 all species →	Domain	Rho GTPase-activating protein, pG1 domain	Interproscan
IPR001806 all species →	Family	Small GTPase	Interproscan
IPR051978 all species →	Family	Rho GTPase-activating domain-containing protein	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46005 all species →	RHO GTPASE-ACTIVATING PROTEIN 190	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0007165 all species →	Biological Process	signal transduction	Interproscan
GO:0003924 all species →	Molecular Function	GTPase activity	Interproscan
GO:0005525 all species →	Molecular Function	GTP binding	Interproscan
GO:0005096 all species →	Molecular Function	GTPase activator activity	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0007266 all species →	Biological Process	Rho protein signal transduction	Interproscan
GO:0008361 all species →	Biological Process	regulation of cell size	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K13709	ARHGAP5; Rho GTPase-activating protein 5	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Anthopleura xanthogrammica tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Anthopleura xanthogrammica, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →