Genomic Location: chr11:3230463...3244562
NR annotation: XP_031558032.1, neurogenic locus notch homolog protein 2-like isoform X2 [Actinia tenebrosa]
Species Anthopleura xanthogrammica · all data for this species · gene families
| CDS |
| ENSOJPT00000021712 |
| Transcript |
| ENSOJPT00000021712 |
| Protein |
| ENSOJPP00000018692.1 |
| UniProt accession | Description |
|---|---|
| Q04721 | Neurogenic locus notch homolog protein 2 OS=Homo sapiens OX=9606 GN=NOTCH2 PE=1 SV=3 |
| O35516 | Neurogenic locus notch homolog protein 2 OS=Mus musculus OX=10090 GN=Notch2 PE=1 SV=2 |
| Q9QW30 | Neurogenic locus notch homolog protein 2 OS=Rattus norvegicus OX=10116 GN=Notch2 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003337 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF12796 all species → | Ank_2 | Ankyrin repeats (3 copies) | Repeat | Interproscan |
| PF00023 all species → | Ank | Ankyrin repeat | Repeat | Interproscan |
| PF00008 all species → | EGF | EGF-like domain | Domain | Interproscan |
| PF07684 all species → | NODP | NOTCH protein | Family | Interproscan |
| PF06816 all species → | NOD | NOTCH protein | Family | Interproscan |
| PF13857 all species → | Ank_5 | Ankyrin repeats (many copies) | Repeat | Interproscan |
| PF07974 all species → | EGF_2 | EGF-like domain | Domain | Interproscan |
| PF00066 all species → | Notch | LNR domain | Domain | Interproscan |
| PF07645 all species → | EGF_CA | Calcium-binding EGF domain | Domain | Interproscan |
| PF12661 all species → | hEGF | Human growth factor-like EGF | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR009030 all species → | Homologous_superfamily | Growth factor receptor cysteine-rich domain superfamily | Interproscan |
| IPR000742 all species → | Domain | EGF-like domain | Interproscan |
| IPR002110 all species → | Repeat | Ankyrin repeat | Interproscan |
| IPR018097 all species → | Conserved_site | EGF-like calcium-binding, conserved site | Interproscan |
| IPR000152 all species → | PTM | EGF-type aspartate/asparagine hydroxylation site | Interproscan |
| IPR011656 all species → | Domain | Notch, NODP domain | Interproscan |
| IPR000800 all species → | Domain | Notch domain | Interproscan |
| IPR036770 all species → | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR001881 all species → | Domain | EGF-like calcium-binding domain | Interproscan |
| IPR010660 all species → | Domain | Notch, NOD domain | Interproscan |
| IPR013111 all species → | Domain | EGF-like domain, extracellular | Interproscan |
| IPR008297 all species → | Family | Notch | Interproscan |
| IPR035993 all species → | Homologous_superfamily | Notch-like domain superfamily | Interproscan |
| IPR049883 all species → | Domain | NOTCH1 EGF-like calcium-binding domain | Interproscan |
| IPR013032 all species → | Conserved_site | EGF-like, conserved site | Interproscan |
| IPR051022 all species → | Family | Notch Signaling and Cell Fate Determination | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR24049 all species → | CRUMBS FAMILY MEMBER | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0007219 all species → | Biological Process | Notch signaling pathway | Interproscan |
| GO:0007275 all species → | Biological Process | multicellular organism development | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0030154 all species → | Biological Process | cell differentiation | Interproscan |
| GO:0050793 all species → | Biological Process | regulation of developmental process | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007157 all species → | Biological Process | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | Interproscan |
| GO:0032991 all species → | Cellular Component | protein-containing complex | Interproscan |
| GO:0045197 all species → | Biological Process | establishment or maintenance of epithelial cell apical/basal polarity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K02599 | NOTCH1; Notch 1 | - | Endocrine resistance | ko01522 | deepkoala |
