Detailed information of ENSOJPP00000020805.1 in Anthopleura xanthogrammica

Genomic Location: chr12:2561613...2567507
NR annotation: XP_031572036.1, glyoxylate reductase/hydroxypyruvate reductase-like [Actinia tenebrosa]
Species Anthopleura xanthogrammica · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q9UBQ7Glyoxylate reductase/hydroxypyruvate reductase OS=Homo sapiens OX=9606 GN=GRHPR PE=1 SV=1
Q91Z53Glyoxylate reductase/hydroxypyruvate reductase OS=Mus musculus OX=10090 GN=Grhpr PE=1 SV=1
A1RYE4Glyoxylate reductase OS=Thermofilum pendens (strain DSM 2475 / Hrk 5) OX=368408 GN=gyaR PE=3 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001244 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02826
all species →		2-Hacid_dh_CD-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domainDomainInterproscan
PF00389
all species →		2-Hacid_dhD-isomer specific 2-hydroxyacid dehydrogenase, catalytic domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR006140
all species →		DomainD-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domainInterproscan
IPR029753
all species →		Conserved_siteD-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved siteInterproscan
IPR036291
all species →		Homologous_superfamilyNAD(P)-binding domain superfamilyInterproscan
IPR050223
all species →		FamilyD-isomer specific 2-hydroxyacid dehydrogenaseInterproscan
IPR006139
all species →		DomainD-isomer specific 2-hydroxyacid dehydrogenase, catalytic domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10996
all species →		2-HYDROXYACID DEHYDROGENASE-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0051287
all species →		Molecular FunctionNAD bindingInterproscan
GO:0005829
all species →		Cellular ComponentcytosolInterproscan
GO:0008465
all species →		Molecular Functionhydroxypyruvate reductase (NADH) activityInterproscan
GO:0016618
all species →		Molecular Functionhydroxypyruvate reductase [NAD(P)H] activityInterproscan
GO:0030267
all species →		Molecular Functionglyoxylate reductase (NADPH) activityInterproscan
GO:0016616
all species →		Molecular Functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K00049GRHPR; glyoxylate/hydroxypyruvate reductaseEC:1.1.1.79
EC:1.1.1.81
Glycine, serine and threonine metabolismko00260deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Anthopleura xanthogrammica tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Anthopleura xanthogrammica, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix–
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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