Genomic Location: chr7:1551477...1556545
NR annotation: XP_020896902.1, E3 ubiquitin-protein ligase FANCL [Exaiptasia diaphana]
Species Anthopleura xanthogrammica · all data for this species · gene families
| CDS |
| ENSOJPT00000026561 |
| Transcript |
| ENSOJPT00000026561 |
| Protein |
| ENSOJPP00000023026.1 |
| UniProt accession | Description |
|---|---|
| Q9NW38 | E3 ubiquitin-protein ligase FANCL OS=Homo sapiens OX=9606 GN=FANCL PE=1 SV=2 |
| Q9CR14 | E3 ubiquitin-protein ligase FANCL OS=Mus musculus OX=10090 GN=Fancl PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005658 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF11793 all species → | FANCL_C | FANCL C-terminal domain | Domain | Interproscan |
| PF18891 all species → | FANCL_d3 | FANCL UBC-like domain 3 | Domain | Interproscan |
| PF09765 all species → | FANCL_d1 | FANCL UBC-like domain 1 | Domain | Interproscan |
| PF18890 all species → | FANCL_d2 | FANCL UBC-like domain 2 | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR026848 all species → | Family | E3 ubiquitin-protein ligase FANCL | Interproscan |
| IPR026850 all species → | Domain | FANCL C-terminal domain | Interproscan |
| IPR043003 all species → | Homologous_superfamily | FANCL, UBC-like domain 3 superfamily | Interproscan |
| IPR044037 all species → | Domain | FANCL, UBC-like domain 3 | Interproscan |
| IPR019162 all species → | Domain | Fanconi anemia complex, subunit FancL, WD-repeat containing domain | Interproscan |
| IPR043898 all species → | Domain | FANCL, UBC-like domain 2 | Interproscan |
| IPR016135 all species → | Homologous_superfamily | Ubiquitin-conjugating enzyme/RWD-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13206 all species → | UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004842 all species → | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0006281 all species → | Biological Process | DNA repair | Interproscan |
| GO:0006513 all species → | Biological Process | protein monoubiquitination | Interproscan |
| GO:0036297 all species → | Biological Process | interstrand cross-link repair | Interproscan |
| GO:0043240 all species → | Cellular Component | Fanconi anaemia nuclear complex | Interproscan |
| GO:0061630 all species → | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10606 | FANCL, PHF9; E3 ubiquitin-protein ligase FANCL | EC:2.3.2.27 | DNA repair and recombination proteins | ko03400 | deepkoala |
Genes whose expression across the transcriptome samples of Anthopleura xanthogrammica tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Anthopleura xanthogrammica, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |