Genomic Location: chr1:1570351...1589757
NR annotation: XP_031551841.1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like [Actinia tenebrosa]
Species Anthopleura xanthogrammica · all data for this species · gene families
| CDS |
| ENSOJPT00000037040 |
| Transcript |
| ENSOJPT00000037040 |
| Protein |
| ENSOJPP00000031925.1 |
| UniProt accession | Description |
|---|---|
| Q15147 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3 |
| Q9QW07 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Rattus norvegicus OX=10116 GN=Plcb4 PE=1 SV=2 |
| Q07722 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (Fragment) OS=Bos taurus OX=9913 GN=PLCB4 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001136 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00388 all species → | PI-PLC-X | Phosphatidylinositol-specific phospholipase C, X domain | Family | Interproscan |
| PF09279 all species → | EF-hand_like | Phosphoinositide-specific phospholipase C, efhand-like | Domain | Interproscan |
| PF00387 all species → | PI-PLC-Y | Phosphatidylinositol-specific phospholipase C, Y domain | Family | Interproscan |
| PF17787 all species → | PH_14 | PH domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000008 all species → | Domain | C2 domain | Interproscan |
| IPR042531 all species → | Homologous_superfamily | Phospholipase C-beta, C-terminal domain superfamily | Interproscan |
| IPR000909 all species → | Domain | Phosphatidylinositol-specific phospholipase C, X domain | Interproscan |
| IPR015359 all species → | Domain | Phosphoinositide-specific phospholipase C, EF-hand-like domain | Interproscan |
| IPR017946 all species → | Homologous_superfamily | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily | Interproscan |
| IPR001192 all species → | Family | Phosphoinositide phospholipase C family | Interproscan |
| IPR001711 all species → | Domain | Phospholipase C, phosphatidylinositol-specific, Y domain | Interproscan |
| IPR035892 all species → | Homologous_superfamily | C2 domain superfamily | Interproscan |
| IPR037862 all species → | Domain | PLC-beta, PH domain | Interproscan |
| IPR011992 all species → | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR016280 all species → | Family | Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10336 all species → | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0006629 all species → | Biological Process | lipid metabolic process | Interproscan |
| GO:0008081 all species → | Molecular Function | phosphoric diester hydrolase activity | Interproscan |
| GO:0035556 all species → | Biological Process | intracellular signal transduction | Interproscan |
| GO:0004435 all species → | Molecular Function | phosphatidylinositol phospholipase C activity | Interproscan |
| GO:0007165 all species → | Biological Process | signal transduction | Interproscan |
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0048015 all species → | Biological Process | phosphatidylinositol-mediated signaling | Interproscan |
| GO:0051209 all species → | Biological Process | release of sequestered calcium ion into cytosol | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K05858 | PLCB; phosphatidylinositol phospholipase C, beta | EC:3.1.4.11 | Membrane trafficking | ko04131 | deepkoala |
Genes whose expression across the transcriptome samples of Anthopleura xanthogrammica tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Anthopleura xanthogrammica, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
