Genomic Location: :...
NR annotation: XP_031556504.1, beta-secretase 2-like [Actinia tenebrosa]
| CDS | |||||
| ENSOJPT00000043266 | |||||
| Transcript |
| ENSOJPT00000043266 |
| Protein |
| ENSOJPP00000037342.1 |
| Uniprot term | Description |
|---|---|
| W8W138 | Beta-secretase OS=Strongylocentrotus purpuratus OX=7668 GN=BACE PE=2 SV=1 |
| Q9Y5Z0 | Beta-secretase 2 OS=Homo sapiens OX=9606 GN=BACE2 PE=1 SV=1 |
| Q6IE75 | Beta-secretase 2 OS=Rattus norvegicus OX=10116 GN=Bace2 PE=2 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00026 | Asp | Eukaryotic aspartyl protease | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR033121 | Domain | Peptidase family A1 domain | Interproscan |
| IPR021109 | Homologous_superfamily | Aspartic peptidase domain superfamily | Interproscan |
| IPR001461 | Family | Aspartic peptidase A1 family | Interproscan |
| IPR001969 | Active_site | Aspartic peptidase, active site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR47965 | ASPARTYL PROTEASE-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004190 | Molecular Function | aspartic-type endopeptidase activity | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0005768 | Cellular Component | endosome | Interproscan |
| GO:0005802 | Cellular Component | trans-Golgi network | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0006509 | Biological Process | membrane protein ectodomain proteolysis | Interproscan |
| GO:0050435 | Biological Process | amyloid-beta metabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K07747 | BACE2; beta-site APP-cleaving enzyme 2 (memapsin 1) | EC:3.4.23.45 | Peptidases and inhibitors | ko01002 | deepkoala |