Gene detail

Detailed information of ENSPTBP00000028016.1 in Oculina arbuscula

Genomic Location: chr5:25289262...25303512
NR annotation: CAH3164419.1, unnamed protein product, partial [Porites lobata]
Species Oculina arbuscula · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSPTBT00000029306

CTTGGAATAACTCAAATGTTTGAGTGGCAAGCCGACTGTCTCCGCACAGGAAAGGTGCTTACTGGGGGTAACTTGGTATACTCAGCCCCAACAAGTGCAGGGAAAACAATGGTTGCAGAGTTGTTGATGCTAAAACGAGTGCTGGAAACAAAGAGGAAAGCGCTCTTTATTCTTCCTTTTATCAGCGTGGCgcgtgaaaaaatgttttatctcCAGCGTCTATACCAAGAGGCAGGGGTGCGAGTTGAGGGGTACATGGGTAGCCACGCCCCACCTGGGGGCTTTGTTTCTGTAGATATCGCAGTGTGCACAATAGAGAAAGCCAACAGTCTGCTGAATCGTCTGCTGGAAGAAAATAAAGCAATGTCTTCTCTTGGAATTGTAGTGGTGGATGAAATGCACATGATTGGTGATTCACACAGAGGATATCTACTGGAGCTGTTTTTGACCAAAATACGATACATTGCTGGCTGTAACGGACAAAAAACATTTCCCGCAATACAGATAGTCGGCATGAGTGCGACCTTACCCAACCTGGACATGCTCGCAAAGTGGTTATCCGCTGACTTGTACTTCACGGACCACAGGCCTGTTCCGCTGACGGAAATGGTCAAAGTAGGCTCTACACTCTATGACGCTAACATGGAGAGGATTCGTGAAATCAGCGGTGGGACTGTCAGTGGGGACGAAGATCACGTGATACCGCTGTGTAAGGAAACCATCGTCGACGGACACTCGGTCTTAGTCTTCTGTCCGACAAAAAACTGGTGTGAAAAGCTAGCCGAGACCATCGCGAAACATTTCGCGGAAATAGGAAGCTTAGCGCTTCAAGAAGGGAATAGCAACAGCGTTCGGGACGCTGGGTTTGTGAAAGCTTCTGAACTAATCACTTTTGATTACGCCGCGCTGAAGGAGGTCATAGAGCAGCTAAAACGTACACAAGTAGGGCTGGACGCAGTGCTGTCACGCATGGTACCGCATGGAGTGGCATTTCATCATGCTGGGCTCACCTTTGATGAGAGGGACATTATTGAAGGGGCCTTTAGACAGGGATCCATTCGCGTACTCGTGGCAACGTCTACACTGTCTTCAGGAGTAAACCTTCCCGCTCGTCGTGTTATTATCCGCACGCCAATGTTTCATGGCAAGCTGGTAGATGCTTTAATCTACAAACAGATGGCTGGCCGCGCAGGCCGCAAAGGAGTCGATGCCCTGGGCGAGAGCGTGTTGATCTGTAAACCCGCTGAACGACAGAAAGCGGCTTCGCTGTTGAATTCTCGACTTAAGGCTGTGGAAAGTTGCCTGCTAGGTAAGGAGGAAAATGGTGGAATAAAGCGCGCGCTTCTCGAAGTCATCGCCAGCGGAGTGGTCACCAGGCCCCAGGATGTTGAGCGTTACGCGGCCTGTACGTTCTTCGCTTCAGTACCCGCGCAACAAGATGCAAACGACACAGATGCCGTTATCAAGAAAACCGTGAAGTTTCTGGTGGAAAACGAGTTTGTTCGTTTACAGAAGTGCGATGATAAGAAgacaaatgaaaacaaagaaaataatggcGAAAGGGAGGAGGTAAGTGAGCAGAGATACGTCCCAACTCAACTGGGCGTGGCCACATTATCGTCCGCTCTCTCCCCTGATGAAGCGCTTGTTGTATTTGCTGAGGTGCAGAAAGCACGTAAGTGCTTTGTGCTCGAAAGCGAGCTACACATCATATACCAgGTGACTCCAATCTACATACAAGATCAGTGGCCCAACATAGATTGGTACCAGTACCTGCGCATCTATGAGCGCCTGCCTGCAAACATGCGCCGAGTGGCGGATATGGTGGGAGTAGAAGAAGGTTTCCTTGCCAGAGCCGTGCGAGGCCGTGTTCTGACGCGTACCGAACAGCAGCGCCAATCTCTTGCCGTGCACCGCCGATTCTACGCGGCGTTAGCACTTCAAGACCTTGTACATGAAGTGCCACTCAATATTGTTGCTAGACGGTACGGCGCAAACCGCGGAATGCTGCAATCGCTGCAAGGATCTTCTGCAACGTTTGCTGGAATGGTGACGGTGTTCTGTGAAAAGCTCGGCTGGACCAACATAGAGCTACTTCTGTCACAATTCCAGAGCCGTTTATCTTTTGGTGTCGAGCGAGATCTCTGTGACCTGGTGCGAATTTCTCTCTTGAATGCTGCGCGTGCGCGTATGCTGTACAACGCTGGCTACCACACCATCGCTTCCGTTGCAGCGGCGCCTCCGTCTGAAATTGAGAATATATTGCACAACGCTGCGCCATTCGTCAGCGGGCGCAAGCGAGGCCAAGAAACTGAGACCGAGGTACGTGAACGTAGCGAGGCGCGCGTGATCTGGGTCGCAGGGAGGAGAGGGCTTACTGAAGGAGCGGCCGCCAAGCTTATCGTTGCCGAAGCTAAACAACTGCTACAGGCTGATGTGGCACAGCTAGGAATTCAGTGGAAACCGCCAGAGAGTGATGAAAATACTGGCGGACAAGGTAGTCAAGGTAATTCAACTACTTCCGACGCGACAGAAGGTAGTTCCAAGTCTGTCGGAATGCAACCAGCCGAAGCTTTGCAGAGTGCCGTTGGCTCTAAAACTGTGGGCAGAACAGAAGCAGTCATCGGTAAGCACGTTACAAAGTCAAACGCTGATGCGTCAAGTGACAAGCACAAGGTACACACGAATAGGAAGGTAAAGGAAAGCGGAACGGCCAGACACAGCAATCACCGGCAAGAAATTGCTGGACCAAGTTTACTGGGAAACAAAGTATCCATAGATACGGGCGCAGATTTCTTGAAGCCTTCTTCACAACACGTAGATACAAGAGTGTTAACATACCGCGAAAAAGGCCAAACGGAAGTCCAGAAAGCGGCCAGCATCACATCTGTCTTGAAAGATAATGCTTGCCCCTCTACTTCAAAGCCAGCCCAGGTTTCTGACTGCAAGCAATCCAGGCCTCCTTCGAATACTGTGAACCCCGTTACTCCTTTAGGAAGCGGAACTACTCGCTCAAGAAACAAACGTCGTTCGCCGATACCAGAAATGCCGGAGCCGCAAGAGAAATTACAGAAAAAGGAAACAGCAGCAGTAAACATGCCGGAAGTGAACATACAGAAAGCTATAGTTTCGAAAGTAGTTCTACCTGAAGTGCAGGAAGGGTCAAGCAACTCCACCGCTGTCATGGAGGTTTCAACTGATTCAAAAGTTGGCAACGAAGCCCAGTCGGTTTCTGTTGAGTTGTACTCTGAACCATTCGAAGGAGAGGAACCGGCTGCGAAGGAAAAACCCGATGATGCTGCACTGGCTGCGTATAGTTTGAGTGACACCTGTCTCATGGagtgtgacgtcataattgaaGAGAAAGTCGATAAGTCAACGGCGCATGCGTGTGCCGTGAACGCGACTAACGAACCGCCTGGAAAGGAGCGCGAAGCTTTATGCGATAAAGTAAACATTGCCACTGCTGTAACACCCAGAAGTTTGGCCGCGCTTGAAAGTCAGGATATCATCGGCCAATATGACACTCAGCCACGCTTTCCTGGCACAGGAGAATTTCACGTGGAACAGAGCTTGGAGATTTTGTCGTCATTCGCATCTCCTGTTCTTCAGTCACCGAAATGCTCTATTACAGATGACTTAGCCTCTGTTAGCGCACCAAATTCATTTTCACTTCGTCTGTCGTCCAGCGATGGTTGCCTTGACTCTGATCTGTCTATGCTGGCCGTTGTCGAGCTAATAGAGAAAGAAGTTGATGCAAACAAGAAGAGCCTGCCTGGGGTACCTCACAGTGAGTCAGATtttaccaaaattaaaaacccGAAATCTACGAATTCACCCAAAACCAAAGATGAGAGATCGCCTGCCAAGAAAATGTCACGCAGCGCGGTGACACATGACGATGAAATTGACGGAATTGAAATGCCAGATTCAGACATCGTCCCCTCCACACCCCCAAGAGACAAAAGACCTTCCCAGGACGATTTTAGAACAAAACTTTCAGCCACCCCGTTGTCAACAAGAAAACGTGCTTCTCCGCGACGGTCGCCGTATTCCAATACCCCGGATGAAGGACTTGTGATCATCGACGTCGCAGGACACGAGCAAGTTTTTGCAATGTTCCTTAAAGAATGGCGTAGTCAAACTCGCTTTTCGTTAGCTGTAGCTTGTGAGCGCTTCCTTGATGATGTCCCCAGAATTGGAGGACGATTCAGTAATGCGCCGGCTTCGAAAGGGACCTTGAGGGGCCTTAAGGTGGAAGGCGAGGACCTGGTGGTGGTTGGAGTTGCTGTGAGCTGGGGCGGTAAAGACGCCTATTACGTGTCACTCAAGGAGCATGCTCAGTCGGCACCAAGTCAACCGGACGACAGTCAGGCGGAGTCAGCGGTTGATAGTAATCTGACGCTTGCTCGTCGTGTTAATGCACTGAAGAGTGTCGTTCAGTCCTTGACAGAACGAGGCCGACTCATGGTTTGTTTCGATGTCAAGGAACACTTCAAGACCTTTGCTCGATGTACTGGGATTTCTCTCGGCGGACCTGCGGAGGACCCCAAGGTGGCGAGTTGGCTGTTAGATCCAGGGGCTAAAGAAAAGAACCTTCACCAGCTTGTAGGACAGCACTTACCTGAGGAAGCGCCTCTATTGGAAGGTAGCGGTGGTGGACTGGGAACAGGAGGTCTGGCGCTAGCATACCAATGTCAGCAAAGTGGTAGAGTGAGGGCCTGTGTCGAGTCTGTTGTAGTTCTTTCTTTGATGAAAAAGCTGAGGCCATTACTGGAGGCGGAGGATCTGATGTCAGCATTTACAAAGGTGGAGATGCCATCTGCGCTCTGCTTGGCTCGCATGGAGTTGAATGGCTTAGGATTTTCAGACACAGAAAGCGAACATCTAAAGAACATTTTACAAGCCAAACTACGCACGCTAGAACAGGAAGCCTACCGACTGGCGAATCACAGCTTCTCACTGACCAGTCGCGAAGACGTGGCTCAGAATCTCAGCACCAACAAAGACGTGCTTGAAAGGCTTAAGCCGCTTCACCCGCTACCCGGACTGATCATAGAGTGGCGGCGGATCAACTCTGCCCTAACAAAGGTCGTGTTTCCACTACAGAAGGAAAAGTGTTTGAATGCGAGGCTCAACATGCCACGGATTCACTCCATGAGCCAGACTCACACGGCGACTGGACGAGTTTCATTTGCGGAGCCAAACTTGCAGAATGTTCCCAAAGATTTTGATATAATATTACCAACGACCATTGCTGAGATGAGCATGCGTAACGCCTttgttccttttaaaaatggCGTGCTCCTTGCCGCTGACTATTCTCAGCTTGAGCTGAGGCTCATTGCCCACCTTTCCAACGATGAGCGCCTGCGCAAGATTCTTAACGGAGGAGGGGACGTGTTCAGAATGATCGCGGGCGAACTTTATCGAGCTCCCGCAGAGTCCATTAAAGATAACCAGCGGCAGCACGCTAAACAAGTCTGTTATGGCATCATTTACGGAATTGGCGCCAAAACTCTTGGAGAGCAGCTTGGACTTGCTGAAGAAGAAGCGTCTTTGTTCATTGACAAATTCACGTCGCGTTTTGTTGGTGTGAGGAAGTATTTGAAAGAGACAGTTGAGCAGTGCAAGAAGCAAGGCTATGTAAAGACGGTTACTGGAAGAAAAAGGTTCCTTCCGGCAATCAACTCACCGAACGTGCATGCGCACAGCCAAGCAGCGAGACAAGCTGTCAACACCACGGTGCAAGGGTCAGCGGCAGACTTGGTAAAGACAGCCATGGTTAATATTGACAAGAGGTTGACTGAGACTTTCCCATCGTGCGTTATGACGCATAGACATTCCTCCCCGGATTTACAGGCTACTAAAAGCAAAACCCGGGGGAGACGTTCAAAGTGTGATGTCTCACCGCTCATTGGAGGGTATTTTGTTTTGCAACTTCACGATGAGCTGATATTTGAGGTTGCGGTTAGTGACTTAAGAAGCGTGGCTCAGATTGTTAAAACTGAAATGGAGAACGCTATGAAACTCTCCGTTGTTCTTCCTGTTAAAATGAAGGCTGGTCCTTCCTGGGGAAACATGGCTGAATTTGAATTGTAA

Transcript

ENSPTBT00000029306

Protein

ENSPTBP00000028016.1

LGITQMFEWQADCLRTGKVLTGGNLVYSAPTSAGKTMVAELLMLKRVLETKRKALFILPFISVAREKMFYLQRLYQEAGVRVEGYMGSHAPPGGFVSVDIAVCTIEKANSLLNRLLEENKAMSSLGIVVVDEMHMIGDSHRGYLLELFLTKIRYIAGCNGQKTFPAIQIVGMSATLPNLDMLAKWLSADLYFTDHRPVPLTEMVKVGSTLYDANMERIREISGGTVSGDEDHVIPLCKETIVDGHSVLVFCPTKNWCEKLAETIAKHFAEIGSLALQEGNSNSVRDAGFVKASELITFDYAALKEVIEQLKRTQVGLDAVLSRMVPHGVAFHHAGLTFDERDIIEGAFRQGSIRVLVATSTLSSGVNLPARRVIIRTPMFHGKLVDALIYKQMAGRAGRKGVDALGESVLICKPAERQKAASLLNSRLKAVESCLLGKEENGGIKRALLEVIASGVVTRPQDVERYAACTFFASVPAQQDANDTDAVIKKTVKFLVENEFVRLQKCDDKKTNENKENNGEREEVSEQRYVPTQLGVATLSSALSPDEALVVFAEVQKARKCFVLESELHIIYQVTPIYIQDQWPNIDWYQYLRIYERLPANMRRVADMVGVEEGFLARAVRGRVLTRTEQQRQSLAVHRRFYAALALQDLVHEVPLNIVARRYGANRGMLQSLQGSSATFAGMVTVFCEKLGWTNIELLLSQFQSRLSFGVERDLCDLVRISLLNAARARMLYNAGYHTIASVAAAPPSEIENILHNAAPFVSGRKRGQETETEVRERSEARVIWVAGRRGLTEGAAAKLIVAEAKQLLQADVAQLGIQWKPPESDENTGGQGSQGNSTTSDATEGSSKSVGMQPAEALQSAVGSKTVGRTEAVIGKHVTKSNADASSDKHKVHTNRKVKESGTARHSNHRQEIAGPSLLGNKVSIDTGADFLKPSSQHVDTRVLTYREKGQTEVQKAASITSVLKDNACPSTSKPAQVSDCKQSRPPSNTVNPVTPLGSGTTRSRNKRRSPIPEMPEPQEKLQKKETAAVNMPEVNIQKAIVSKVVLPEVQEGSSNSTAVMEVSTDSKVGNEAQSVSVELYSEPFEGEEPAAKEKPDDAALAAYSLSDTCLMECDVIIEEKVDKSTAHACAVNATNEPPGKEREALCDKVNIATAVTPRSLAALESQDIIGQYDTQPRFPGTGEFHVEQSLEILSSFASPVLQSPKCSITDDLASVSAPNSFSLRLSSSDGCLDSDLSMLAVVELIEKEVDANKKSLPGVPHSESDFTKIKNPKSTNSPKTKDERSPAKKMSRSAVTHDDEIDGIEMPDSDIVPSTPPRDKRPSQDDFRTKLSATPLSTRKRASPRRSPYSNTPDEGLVIIDVAGHEQVFAMFLKEWRSQTRFSLAVACERFLDDVPRIGGRFSNAPASKGTLRGLKVEGEDLVVVGVAVSWGGKDAYYVSLKEHAQSAPSQPDDSQAESAVDSNLTLARRVNALKSVVQSLTERGRLMVCFDVKEHFKTFARCTGISLGGPAEDPKVASWLLDPGAKEKNLHQLVGQHLPEEAPLLEGSGGGLGTGGLALAYQCQQSGRVRACVESVVVLSLMKKLRPLLEAEDLMSAFTKVEMPSALCLARMELNGLGFSDTESEHLKNILQAKLRTLEQEAYRLANHSFSLTSREDVAQNLSTNKDVLERLKPLHPLPGLIIEWRRINSALTKVVFPLQKEKCLNARLNMPRIHSMSQTHTATGRVSFAEPNLQNVPKDFDIILPTTIAEMSMRNAFVPFKNGVLLAADYSQLELRLIAHLSNDERLRKILNGGGDVFRMIAGELYRAPAESIKDNQRQHAKQVCYGIIYGIGAKTLGEQLGLAEEEASLFIDKFTSRFVGVRKYLKETVEQCKKQGYVKTVTGRKRFLPAINSPNVHAHSQAARQAVNTTVQGSAADLVKTAMVNIDKRLTETFPSCVMTHRHSSPDLQATKSKTRGRRSKCDVSPLIGGYFVLQLHDELIFEVAVSDLRSVAQIVKTEMENAMKLSVVLPVKMKAGPSWGNMAEFEL

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O75417	DNA polymerase theta OS=Homo sapiens OX=9606 GN=POLQ PE=1 SV=2
Q8CGS6	DNA polymerase theta OS=Mus musculus OX=10090 GN=Polq PE=1 SV=2
O18475	DNA polymerase theta OS=Drosophila melanogaster OX=7227 GN=PolQ PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004248 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00271 all species →	Helicase_C	Helicase conserved C-terminal domain	Domain	Interproscan
PF20470 all species →	HTH_61	Helix-turn-helix domain	Domain	Interproscan
PF21099 all species →	POLQ_helical	DNA_pol_Q helicase like region helical domain	Domain	Interproscan
PF00270 all species →	DEAD	DEAD/DEAH box helicase	Domain	Interproscan
PF00476 all species →	DNA_pol_A	DNA polymerase family A	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR014001 all species →	Domain	Helicase superfamily 1/2, ATP-binding domain	Interproscan
IPR001650 all species →	Domain	Helicase, C-terminal domain-like	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR046931 all species →	Domain	DNA polymerase theta-like, helix-turn-helix domain	Interproscan
IPR048960 all species →	Domain	POLQ-like, helical domain	Interproscan
IPR011545 all species →	Domain	DEAD/DEAH box helicase domain	Interproscan
IPR002298 all species →	Family	DNA polymerase A	Interproscan
IPR043502 all species →	Homologous_superfamily	DNA/RNA polymerase superfamily	Interproscan
IPR012337 all species →	Homologous_superfamily	Ribonuclease H-like superfamily	Interproscan
IPR019760 all species →	Conserved_site	DNA-directed DNA polymerase, family A, conserved site	Interproscan
IPR001098 all species →	Domain	DNA-directed DNA polymerase, family A, palm domain	Interproscan
IPR036397 all species →	Homologous_superfamily	Ribonuclease H superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10133 all species →	DNA POLYMERASE I	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003676 all species →	Molecular Function	nucleic acid binding	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0003887 all species →	Molecular Function	DNA-directed DNA polymerase activity	Interproscan
GO:0006261 all species →	Biological Process	DNA-templated DNA replication	Interproscan
GO:0006302 all species →	Biological Process	double-strand break repair	Interproscan
GO:0097681 all species →	Biological Process	double-strand break repair via alternative nonhomologous end joining	Interproscan
GO:0006260 all species →	Biological Process	DNA replication	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K02349	POLQ; DNA polymerase theta	EC:2.7.7.7	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Oculina arbuscula tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Oculina arbuscula, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →