Gene detail

Detailed information of ENSPTBP00000041565.1 in Oculina arbuscula

Genomic Location: chr8:2184449...2203808
NR annotation: XP_020611586.1, extended synaptotagmin-2-like isoform X2 [Orbicella faveolata]
Species Oculina arbuscula · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSPTBT00000043524

ATGGCCAGTTGGAAGATTGAACGCTGTGGAAGGGATGCAAGGGTTTTCTTTCCTGACGTGGAAAGAGCAGAATGGCTCAACAAgATGCTGGTTCAACTATGGCCATACATCAATGACATGGTTGTGAAGATTTTAAAAGAGCAAGTTGAGCCAGAGATTCAGAAGAATGTGCCTGGCTTCCTGAGCTCTATTCACTTTGAAGAAATCTCTCTTGGCCAAGTGCCTCCTCGTATAGGTGGAATCAAGACTTACACCCATAATGTAGACCGTAATGAGATAATCATGGATGTCGATTTAATTTACGCCGGTGATTCAGACTTTGAGCTTTCAGTCAAGGGAGTAACTGTTGGTATCGAGGATCTCCAGATACGTGGAAGTCTGCGTGTGATCCTGCGCCCTCTTATCCCAGCTGCGCCTCTTGTAGGCGGGGTCTCTGTCTTCTTCCTTAACAGACCGgaTATTGACTTTGATTTAACAAACATGGCAAATATCCTTGATATTCCAGGTCTAAGTGACATTATCCGTGGAGTGATAGATGATGTTGTAGCTGGATTTGTAGTTCTTCCAAACAGGATCACAGTTCCTCTGACCGACGTTGATCCATATGAACTCAAATACCCCTTGCCTGATGGAGTTCTTCGAATTGAAGTTCTGGAAGCTAAAGATTTGGTCAAGAAGGATATTGGTGTTTTCAAGAAAGGCTCTTCTGATCCATATGTTATACTCCGAGTGGGTGCCAAGACATTCCGCACGCAGACAAAAGACAGCACACTGAACCCAGTTTGGAATGAAGTGTTTGAGTCCTTTGTTGATAACGCTCATGGACAGAAGATAAAGATTGGTGTCTTTGACGAGGACAAGGCATCTGATGATGAAGCCCTTGGCACtgTTGAAGCCGACATTGCTACCATTGTCCAACAAGGCAATGTTGATCTGTGGCTTCCACTAGAGAATGTAGAAAGTGGCCAGATCAATTTGCGGTGTACTTGGTTCTCGCTGACCCCCAAGCCTGAGGATCTGTCACCGGCTGAGCAGGCTGTCCAGGGAGAGGAGATGTTAGCCACAGCAGCTTTGTTTGTGAAGTTGGATTCTGCCAAGAATCTCCCTATCACAAATCCTGCACGCGGCACAACAAGTGCATTCTGCAAACTAACTGTTGGAAATGTAACTCTCCAGAGCAAGACCATTCAGGATTCTAACAGTCCCGTGTGGGAAGAGCCATTCCGCTTCCTGATCCACGATCCAAAATATCAGGAGCTGGATATTGAGATTATTGACAGTGGAAAGGAGAAAACTATTGGCAAGCTGGAATTCTCACTAGCTCAACTGCTCAAGAGTGAGAATATGACATTTGAACAGCCCTTCCCTCTGAAGGAATCTGGCCATAACAGTACTTTGACCTGCAGGTTTACTCTAAAGGCCTTGTTCACAAGAGATGACGACACTTCAGACGAGGAGGAAGATGAAGCAGAAGCACCTGACATGATAGCTGCTGAGGAGTTGCATGCTGGTGGTGCAAGCAAGCAAAGCGAGGAAAGCACTGTCAGACGTAGAAAACCTGCCCCGAAAGTTCAAAGGACTGTATCTGGCGACGTTCAGCTTACCACAAGATACAACAAACAGGGCAGCAAGGTGGAGGTTATTGTTCACCAAGCAAGGAACTTGCTGGCTTGTGACTCAGATGGTCTTTCTGATCCATATGTCCGAGCTTATCTACTCCCTGACAAGTCTCGCAGTGGACGCCGACGAACTGATGTCAAGAAAAACACTCTGGAGCCAACTTGGGATGAGACgtTTGACTGGTTTGTCCCAGAGGACCAGCTCAAAGAGCGCACTCTCGACATAACTGTTAAGAATGATGTGTCATTCTTTTCAAAAAGCAAGACTTCCATGGGTCAGGTTCTGCTTGACCTTGGTAAACTGGACTTATCCCAGGCTGTCACTGAGTGGTATATGTTGCGTGACGAGAAAAAGGAAGATGATGACTGA

Transcript

ENSPTBT00000043524

ACTGCAAGATTTGAATGCGCACCTAGCTGTCTGCAACAGATCTTGAAATCATTTCACCAAGCTGCGAAAATATCAAGGAAAATGGCCAGTTGGAAGATTGAACGCTGTGGAAGGGATGCAAGGGTTTTCTTTCCTGACGTGGAAAGAGCAGAATGGCTCAACAAgATGCTGGTTCAACTATGGCCATACATCAATGACATGGTTGTGAAGATTTTAAAAGAGCAAGTTGAGCCAGAGATTCAGAAGAATGTGCCTGGCTTCCTGAGCTCTATTCACTTTGAAGAAATCTCTCTTGGCCAAGTGCCTCCTCGTATAGGTGGAATCAAGACTTACACCCATAATGTAGACCGTAATGAGATAATCATGGATGTCGATTTAATTTACGCCGGTGATTCAGACTTTGAGCTTTCAGTCAAGGGAGTAACTGTTGGTATCGAGGATCTCCAGATACGTGGAAGTCTGCGTGTGATCCTGCGCCCTCTTATCCCAGCTGCGCCTCTTGTAGGCGGGGTCTCTGTCTTCTTCCTTAACAGACCGgaTATTGACTTTGATTTAACAAACATGGCAAATATCCTTGATATTCCAGGTCTAAGTGACATTATCCGTGGAGTGATAGATGATGTTGTAGCTGGATTTGTAGTTCTTCCAAACAGGATCACAGTTCCTCTGACCGACGTTGATCCATATGAACTCAAATACCCCTTGCCTGATGGAGTTCTTCGAATTGAAGTTCTGGAAGCTAAAGATTTGGTCAAGAAGGATATTGGTGTTTTCAAGAAAGGCTCTTCTGATCCATATGTTATACTCCGAGTGGGTGCCAAGACATTCCGCACGCAGACAAAAGACAGCACACTGAACCCAGTTTGGAATGAAGTGTTTGAGTCCTTTGTTGATAACGCTCATGGACAGAAGATAAAGATTGGTGTCTTTGACGAGGACAAGGCATCTGATGATGAAGCCCTTGGCACtgTTGAAGCCGACATTGCTACCATTGTCCAACAAGGCAATGTTGATCTGTGGCTTCCACTAGAGAATGTAGAAAGTGGCCAGATCAATTTGCGGTGTACTTGGTTCTCGCTGACCCCCAAGCCTGAGGATCTGTCACCGGCTGAGCAGGCTGTCCAGGGAGAGGAGATGTTAGCCACAGCAGCTTTGTTTGTGAAGTTGGATTCTGCCAAGAATCTCCCTATCACAAATCCTGCACGCGGCACAACAAGTGCATTCTGCAAACTAACTGTTGGAAATGTAACTCTCCAGAGCAAGACCATTCAGGATTCTAACAGTCCCGTGTGGGAAGAGCCATTCCGCTTCCTGATCCACGATCCAAAATATCAGGAGCTGGATATTGAGATTATTGACAGTGGAAAGGAGAAAACTATTGGCAAGCTGGAATTCTCACTAGCTCAACTGCTCAAGAGTGAGAATATGACATTTGAACAGCCCTTCCCTCTGAAGGAATCTGGCCATAACAGTACTTTGACCTGCAGGTTTACTCTAAAGGCCTTGTTCACAAGAGATGACGACACTTCAGACGAGGAGGAAGATGAAGCAGAAGCACCTGACATGATAGCTGCTGAGGAGTTGCATGCTGGTGGTGCAAGCAAGCAAAGCGAGGAAAGCACTGTCAGACGTAGAAAACCTGCCCCGAAAGTTCAAAGGACTGTATCTGGCGACGTTCAGCTTACCACAAGATACAACAAACAGGGCAGCAAGGTGGAGGTTATTGTTCACCAAGCAAGGAACTTGCTGGCTTGTGACTCAGATGGTCTTTCTGATCCATATGTCCGAGCTTATCTACTCCCTGACAAGTCTCGCAGTGGACGCCGACGAACTGATGTCAAGAAAAACACTCTGGAGCCAACTTGGGATGAGACgtTTGACTGGTTTGTCCCAGAGGACCAGCTCAAAGAGCGCACTCTCGACATAACTGTTAAGAATGATGTGTCATTCTTTTCAAAAAGCAAGACTTCCATGGGTCAGGTTCTGCTTGACCTTGGTAAACTGGACTTATCCCAGGCTGTCACTGAGTGGTATATGTTGCGTGACGAGAAAAAGGAAGATGATGACTGAAGATGACAACCAATAAGGAGGAAGCAGTGGATTAGCAAGGAACTAGCACATCAAATGGGagaataaaataatttgaaaaaaataaaataaaatgtgtgaTAAAGATTTAAGAGCAAACTGTTTACCAAGAAGTCCTGTGAATATCATAGGATCTGAGTGGGAGTGTCTTCATTCTTTAGCTATAATCATCTAAAATGATTGTAAACTTGCAAGCCACGCAAAACTGTTTTGTTCCTTTGTatgtttttctttgaatttaatttcatttacaTCCTTCCTCTTGccaaactggttttaaaaagttggacttgaaaggtcttgaaaaGCTCATACTAAATAGAGCTAAGCCCAGTCATTCCTCTATCTATTTTCCTTCTTTGATGTACTTGTTGCAACtatttaagaaaaataattttgttttaaagtatGTATCAACCAAGTTTATGCAAGTTCTTCGTAAAACATTAAATCGCCAGTCTATATTTTTAATACTAATTTATACAATAAGTAGATATTTTTCACCTGTTTAGACAGTGATATTCAATGTAAGGTATTTAAAAGTAATTAGCGGTTGCAGCATGAAACCATAGACTAAGAATAATATTTAGCTAAGATACACCAGTGCATTGTTAACAAAGAAATAGAGGGAATGACTTCTAAAAGCTTCGTTTTCTTTCCACATACTTTAATAAACAAATGCAGAATATAGACTTCATACATATATGTTATCTTCAACTCCTTGCTCTTGAATTGACAAGCGGCTGTCAATTTTCCACAGCTTAAAATCTTTAATCTTTAATCTTTAGTTCTATTGTagccttaaaaaaatataatgtaGCATTACTTGGATATTCAAAAATGTTGTGCACATTGTGTAGGGGTAGTATTGTAATGTTGTGAAATAATGGggtaacaataaataataaacaaaataaagtaaatattCAATAAGTCATTGTG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q3TZZ7	Extended synaptotagmin-2 OS=Mus musculus OX=10090 GN=Esyt2 PE=1 SV=1
A0FGR8	Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1
Q5FWL4	Extended synaptotagmin-2-A OS=Xenopus laevis OX=8355 GN=esyt2-a PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001222 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF17047 all species →	SMP_LBD	Synaptotagmin-like mitochondrial-lipid-binding domain	Domain	Interproscan
PF00168 all species →	C2	C2 domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000008 all species →	Domain	C2 domain	Interproscan
IPR037752 all species →	Domain	Extended synaptotagmin, C-terminal C2 domain	Interproscan
IPR039010 all species →	Domain	Synaptotagmin, SMP domain	Interproscan
IPR035892 all species →	Homologous_superfamily	C2 domain superfamily	Interproscan
IPR031468 all species →	Domain	Synaptotagmin-like mitochondrial-lipid-binding domain	Interproscan
IPR037749 all species →	Domain	Extended synaptotagmin, C2B domain	Interproscan
IPR051634 all species →	Family	Extended Synaptotagmin	Interproscan
IPR037733 all species →	Domain	Extended synaptotagmin, C2A domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45761 all species →	EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006869 all species →	Biological Process	lipid transport	Interproscan
GO:0061817 all species →	Biological Process	endoplasmic reticulum-plasma membrane tethering	Interproscan
GO:0008289 all species →	Molecular Function	lipid binding	Interproscan
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0005544 all species →	Molecular Function	calcium-dependent phospholipid binding	Interproscan
GO:0008429 all species →	Molecular Function	phosphatidylethanolamine binding	Interproscan
GO:0031210 all species →	Molecular Function	phosphatidylcholine binding	Interproscan
GO:0031227 all species →	Cellular Component	obsolete intrinsic component of endoplasmic reticulum membrane	Interproscan
GO:0031234 all species →	Cellular Component	extrinsic component of cytoplasmic side of plasma membrane	Interproscan
GO:0035091 all species →	Molecular Function	phosphatidylinositol binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for ENSPTBP00000041565.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Oculina arbuscula tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Oculina arbuscula, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →