Gene detail

Detailed information of ENSQNNP00000001609.1 in Candelabrum cocksii

Genomic Location: chr12:12788255...12805186
NR annotation: XP_047144548.1, calcium-activated potassium channel slowpoke-like isoform X1 [Hydra vulgaris]
Species Candelabrum cocksii · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSQNNT00000001690

ATGTCCGGTTGCCAAGCAAATGTGGAAATACCGATCGCCGAGCGGAAATGGTACTGGTTCATCGCTACCTCTGTTGTCGTGTTTTTTGGCGGTCTCATAACGATTCTGATTGGTCGTTTGATTTTGTACTGCACAGCAAAGGGAAAGAAAATCAGCGATTCATCTTACTGTAAAATCGACGATGACAAACCCGTTGGTGGCTTTTACTTTCGTTTGAAAGAAGGCGCCGGAAATCTCGTTTCCGCTCAAACTCTCCAAGGTCGAATACTTGTCGTTCTgtcgtttgtttttaacctcGCCTCGTTTGTATTGTACATCACGGAATCGAGAAAacCAATAGAGCATTGTTTTGATGTGACTGTGGAGCCGCTATGGAGAGTTGAAATTTGCTTGAATGCGTTTTTTGTATTCCACTTCATTATACGGtttattgcTGCTAATGATAAATTATCATTTTGGTCTGTCGAACTTATGACCTACGTTGATATACTCACTATACCAGCTGTATTTGTCGCTATATATTTTGAAGTGAATTGGTTAGggTTACGCTTTTTACGAGTGGTTTACATGATCAATTTACCTgatattttgcaatttctCAATGTACTGAATGCTGGATCGAGTTTAGAAATGGCGGAgatttttggaaatttcttCTCGCTTTGGCTTTCATCAGCTGGAATCGTACATTTGCTCGAGAATACTGGCGATCCCTGGCCTCCAATCGGTTACTCCAACAAAAATCCAATCAACTTTTTTGACGCCACCTATTTTTTAATGGTTACCATGTCAACAGTGGGGTATGGAGACGAGTATTGTCATACGTATTTGGGAAGATGTTTTGCAATGATGTTCATATGCACAAGTCTCGGTTTATTCGCCTCATACATTCCTGCTATACAAGAGTTCTTCAATTCACACACTAAATACGACAGATCGTTTAAATCAAGACCCGGGAAAAAACATGTAATAGTTGCGGGTCATATCACCGATGAAAGTGTCGCCGCTTTTGCCAAAGACTTCTTGCATCCGGATCGTGAAGAAAATCAAACAACTATAGTATTCATATCACCGAACTATCCATCCCTTAAAATGCAAGTAGATCTTCAGAGGCATGTTACAAAAGTTGCGTATTTTGTTGGTACAATATATCGCTTCTTTGATTGCCATCGCATGAAAATGCGAGAAGCAAACGCGGTTATCATTCTTGCCAACAAAAAATGTAAGGATCCTGATGAAGAAGATGCTGCCAATATAACCAGAGTAATTTCCGTAAAGAATTACCACGAGAAGATGAGATGTATTGTTCAACTCATGCTCAGTAAAAACAAATCCCACTTGATCAACTGTCCACAATGGAATCGTGACCTTGGAGATGACATTGTTTGCATTGACGAGttAAAGCTCGGGTTTATAGCGCAAAGCTGCAATGCTCCCGGTTTCTCAACATTGCTGGCGAATCTATTCGCAATGAGAAGCAATACGATCAGCGAGGAGATTTTAGAGCACGAACAATGGAAGGTGGCGTACATGACCGGCGCCGCGAATGAAATGTATACCACAAGACTTTCCAACGCGTTTGTGGGGATGTCTTTTCCCAACGCAGTTGAATTGTGTTTCCAGAAATTGAATTTGATGTTGATCGCGATCGAGATGAAAATATCAGAGAAGAAAACATATTTCGCTATCAacccaaacaacaaaaagttaaagaTTTTGGAAAACACGCGTGGCTACTTTTTTGCACAAGACGCCAATGATGTTTCTCGAGCCAGTCGTTATTGTGATGAGTGTCACGTTGTCATCGTCAATCCAACCGAGATGAAGAAGTGTAAATGTGGCAAGAAAAGGATTCATAGCTCACTCAAGTTCACTTACCTCAGCGATAAACTCGCGTCCAGGTCAGATGACATCAGAGTTAATCTAGAGGCGCCCGTACAGCTGGAACGCAAGGTCAGCGAATTAACTGGGGACTTTCACCCAAACGGTGAACAACCAAAATTCGACCAGAGTGGAACGTTCTACTGGTGTGAAGCGAGAATGTTCGAAGAGGCTCAGATTTCTCTAAAAGCAGCTGCGTCAGAGAAGTTCTGCAACCACGTGGTCGTGCTGGTGCTATCAGGGAAAGGCTCTCCACCACTTGGTTTACGACAGCTgGTGTTACCTCTACGAGCCAGTAACAACAACCCTGCCTCCCTTCGTAAAGTTGTCATCCTTGGTGACAAAGACTTTCTAGGGAGAGAGTGGGACCACCTGGCGAATTTCCCCGATGTAGAAATTGTACCTGGGTCGCCTTATAATCGTTCTGACTTGCGCGCTGTAAACGTAAATACTGCTGACATGTGCATTTTACTGTCACCTGGACATGGCTCAGAAAATGACGAACATCAAGCTCTCTCTGATAAAGAAGTCATTCTTGTTACTCTGAATCTGAAAGCCATGCTTTTCGACCAATCGGAGTTATACTTCAACGAGCCAACAATTAAACTAGCTTCTACCGGCGGCACAATCGATCTGGATTTAAAAGCGTCGCAGAACGGGACAAAGAACTCGAAAAGCCGTTCGATGATTGCAATGAAGAAGACGAATCAAGATGAGCTGATGACTAAGCCTGGAAGATCGATTGGATCTTTGAGAGGGATGAGCATCCCCTTGGTAACAGAGCTAGTTTTCGATTCGAATGCCATGTATTTGGACCAAGACGATATGAACATTTATGATGACGATGGCATCTTTTTAACTCAACCTTACGCATGTGGTTCGGCATTCACAGTCTCTGTACTCGACTCGCTCGTTAGTGCGACATACTTCAACAGTCACGTGCTGACGTTGGTTCGTAACTTGGTAACGGGAAGTGTAAGTCCGGAACTCGATGAGTTAATCGCTGAAGGCAAGACGCCGAAAGGTTCCTACGAAACCCCTGAGATCGCCGCTGTGAGAGACCGGTGCTTGGTGTCCCAGATCTCATTATTTGATGGGCCCTTGTCGACGTTTGGGGATGGCGGTTTATTTGGTGACCTGTTCCTTCATTCATTACGTCAATACAACATGATATGTCTCGGTTTGTATCGATTCCGTGACCAACAGCGCTCCACCACAGGTGTCCCTTGCACCAAGCGTTACGTCATCACATTTCCGCCATTCAATTTCGTGCTCGTGCCAACAGATCTTGTATTCGTGCTCATGCAGTTCAACAAAATAAGCACCAAGAAACGACGCAGGTGGACCAATGTGATGGAGTGA

Transcript

ENSQNNT00000001690

CGTAATTCGTTTGAATGGAACGGCTATTGAAAAACATGATGTGCTTTACAAACGGAAATCAAGATATGGTTTCGAATCGTAAATGGGTAGATAAAATATGGTTGGTAAAGGGTAGAAGCTGAAACAATAATTACGGCTCCACCAATGTCCGGTTGCCAAGCAAATGTGGAAATACCGATCGCCGAGCGGAAATGGTACTGGTTCATCGCTACCTCTGTTGTCGTGTTTTTTGGCGGTCTCATAACGATTCTGATTGGTCGTTTGATTTTGTACTGCACAGCAAAGGGAAAGAAAATCAGCGATTCATCTTACTGTAAAATCGACGATGACAAACCCGTTGGTGGCTTTTACTTTCGTTTGAAAGAAGGCGCCGGAAATCTCGTTTCCGCTCAAACTCTCCAAGGTCGAATACTTGTCGTTCTgtcgtttgtttttaacctcGCCTCGTTTGTATTGTACATCACGGAATCGAGAAAacCAATAGAGCATTGTTTTGATGTGACTGTGGAGCCGCTATGGAGAGTTGAAATTTGCTTGAATGCGTTTTTTGTATTCCACTTCATTATACGGtttattgcTGCTAATGATAAATTATCATTTTGGTCTGTCGAACTTATGACCTACGTTGATATACTCACTATACCAGCTGTATTTGTCGCTATATATTTTGAAGTGAATTGGTTAGggTTACGCTTTTTACGAGTGGTTTACATGATCAATTTACCTgatattttgcaatttctCAATGTACTGAATGCTGGATCGAGTTTAGAAATGGCGGAgatttttggaaatttcttCTCGCTTTGGCTTTCATCAGCTGGAATCGTACATTTGCTCGAGAATACTGGCGATCCCTGGCCTCCAATCGGTTACTCCAACAAAAATCCAATCAACTTTTTTGACGCCACCTATTTTTTAATGGTTACCATGTCAACAGTGGGGTATGGAGACGAGTATTGTCATACGTATTTGGGAAGATGTTTTGCAATGATGTTCATATGCACAAGTCTCGGTTTATTCGCCTCATACATTCCTGCTATACAAGAGTTCTTCAATTCACACACTAAATACGACAGATCGTTTAAATCAAGACCCGGGAAAAAACATGTAATAGTTGCGGGTCATATCACCGATGAAAGTGTCGCCGCTTTTGCCAAAGACTTCTTGCATCCGGATCGTGAAGAAAATCAAACAACTATAGTATTCATATCACCGAACTATCCATCCCTTAAAATGCAAGTAGATCTTCAGAGGCATGTTACAAAAGTTGCGTATTTTGTTGGTACAATATATCGCTTCTTTGATTGCCATCGCATGAAAATGCGAGAAGCAAACGCGGTTATCATTCTTGCCAACAAAAAATGTAAGGATCCTGATGAAGAAGATGCTGCCAATATAACCAGAGTAATTTCCGTAAAGAATTACCACGAGAAGATGAGATGTATTGTTCAACTCATGCTCAGTAAAAACAAATCCCACTTGATCAACTGTCCACAATGGAATCGTGACCTTGGAGATGACATTGTTTGCATTGACGAGttAAAGCTCGGGTTTATAGCGCAAAGCTGCAATGCTCCCGGTTTCTCAACATTGCTGGCGAATCTATTCGCAATGAGAAGCAATACGATCAGCGAGGAGATTTTAGAGCACGAACAATGGAAGGTGGCGTACATGACCGGCGCCGCGAATGAAATGTATACCACAAGACTTTCCAACGCGTTTGTGGGGATGTCTTTTCCCAACGCAGTTGAATTGTGTTTCCAGAAATTGAATTTGATGTTGATCGCGATCGAGATGAAAATATCAGAGAAGAAAACATATTTCGCTATCAacccaaacaacaaaaagttaaagaTTTTGGAAAACACGCGTGGCTACTTTTTTGCACAAGACGCCAATGATGTTTCTCGAGCCAGTCGTTATTGTGATGAGTGTCACGTTGTCATCGTCAATCCAACCGAGATGAAGAAGTGTAAATGTGGCAAGAAAAGGATTCATAGCTCACTCAAGTTCACTTACCTCAGCGATAAACTCGCGTCCAGGTCAGATGACATCAGAGTTAATCTAGAGGCGCCCGTACAGCTGGAACGCAAGGTCAGCGAATTAACTGGGGACTTTCACCCAAACGGTGAACAACCAAAATTCGACCAGAGTGGAACGTTCTACTGGTGTGAAGCGAGAATGTTCGAAGAGGCTCAGATTTCTCTAAAAGCAGCTGCGTCAGAGAAGTTCTGCAACCACGTGGTCGTGCTGGTGCTATCAGGGAAAGGCTCTCCACCACTTGGTTTACGACAGCTgGTGTTACCTCTACGAGCCAGTAACAACAACCCTGCCTCCCTTCGTAAAGTTGTCATCCTTGGTGACAAAGACTTTCTAGGGAGAGAGTGGGACCACCTGGCGAATTTCCCCGATGTAGAAATTGTACCTGGGTCGCCTTATAATCGTTCTGACTTGCGCGCTGTAAACGTAAATACTGCTGACATGTGCATTTTACTGTCACCTGGACATGGCTCAGAAAATGACGAACATCAAGCTCTCTCTGATAAAGAAGTCATTCTTGTTACTCTGAATCTGAAAGCCATGCTTTTCGACCAATCGGAGTTATACTTCAACGAGCCAACAATTAAACTAGCTTCTACCGGCGGCACAATCGATCTGGATTTAAAAGCGTCGCAGAACGGGACAAAGAACTCGAAAAGCCGTTCGATGATTGCAATGAAGAAGACGAATCAAGATGAGCTGATGACTAAGCCTGGAAGATCGATTGGATCTTTGAGAGGGATGAGCATCCCCTTGGTAACAGAGCTAGTTTTCGATTCGAATGCCATGTATTTGGACCAAGACGATATGAACATTTATGATGACGATGGCATCTTTTTAACTCAACCTTACGCATGTGGTTCGGCATTCACAGTCTCTGTACTCGACTCGCTCGTTAGTGCGACATACTTCAACAGTCACGTGCTGACGTTGGTTCGTAACTTGGTAACGGGAAGTGTAAGTCCGGAACTCGATGAGTTAATCGCTGAAGGCAAGACGCCGAAAGGTTCCTACGAAACCCCTGAGATCGCCGCTGTGAGAGACCGGTGCTTGGTGTCCCAGATCTCATTATTTGATGGGCCCTTGTCGACGTTTGGGGATGGCGGTTTATTTGGTGACCTGTTCCTTCATTCATTACGTCAATACAACATGATATGTCTCGGTTTGTATCGATTCCGTGACCAACAGCGCTCCACCACAGGTGTCCCTTGCACCAAGCGTTACGTCATCACATTTCCGCCATTCAATTTCGTGCTCGTGCCAACAGATCTTGTATTCGTGCTCATGCAGTTCAACAAAATAAGCACCAAGAAACGACGCAGGTGGACCAATGTGATGGAGTGAACTTAACATTTTTACGCCAGTTACCTCGAGTCGTGCCGAATTTACGGATGCCGAAAaacgaaaatgttttatagaaatttcttatttattaaaatttcttttgtttttgaatagtTGCCGTCAACGACTATGTCTTGAATACGATGCCTTATCTGAGATTTCGAGATTCTTGCATTTCCAAATAGACCCCTTG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8AYS8	Calcium-activated potassium channel subunit alpha-1 OS=Gallus gallus OX=9031 GN=KCNMA1 PE=1 SV=2
O18867	Calcium-activated potassium channel subunit alpha-1 (Fragment) OS=Macaca mulatta OX=9544 GN=KCNMA1 PE=2 SV=1
Q90ZC7	Calcium-activated potassium channel subunit alpha-1 OS=Xenopus laevis OX=8355 GN=kcnma1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001513 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF21014 all species →	Slowpoke_C	Ca2+-activated K+ channel Slowpoke, TrkA_C like domain	Domain	Interproscan
PF03493 all species →	BK_channel_a	Calcium-activated BK potassium channel alpha subunit	Family	Interproscan
PF07885 all species →	Ion_trans_2	Ion channel	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR048735 all species →	Domain	Ca2+-activated K+ channel Slowpoke-like, C-terminal domain	Interproscan
IPR047871 all species →	Family	Calcium-activated potassium channel slowpoke-like	Interproscan
IPR003929 all species →	Domain	Calcium-activated potassium channel BK, alpha subunit	Interproscan
IPR027359 all species →	Homologous_superfamily	Voltage-dependent channel domain superfamily	Interproscan
IPR013099 all species →	Domain	Potassium channel domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10027 all species →	CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005267 all species →	Molecular Function	potassium channel activity	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0045211 all species →	Cellular Component	postsynaptic membrane	Interproscan
GO:0060072 all species →	Molecular Function	large conductance calcium-activated potassium channel activity	Interproscan
GO:0071805 all species →	Biological Process	potassium ion transmembrane transport	Interproscan
GO:0006813 all species →	Biological Process	potassium ion transport	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04936	KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1	-	Ion channels	ko04040	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Candelabrum cocksii tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Candelabrum cocksii, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →