Gene detail

Detailed information of ENSQNNP00000014969.1 in Candelabrum cocksii

Genomic Location: chr7:1307200...1313579
NR annotation: XP_047128390.1, legumain-like [Hydra vulgaris]
Species Candelabrum cocksii · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSQNNT00000015502

TCAGACTTTATAAAACGAAAGTCGTCCTTTGATGTTttcatttcagttttttatttaGCCTAGAACAGGAAAGATTATTTTGCCTCAGCTCTTAAAAGATGAAGTATCTGTTACTTTGTTcgtttgcaatatttttcctGCAACTCTCTGAGTGCAAACATTGGGCACTTGTCGTAGCTGGATCAAACGGATGGTTTAATTACAGGCACCAGGCTGATGTTTGCCACTCTTATCACATTTTACACAAACATGGAGTGCCCGATGAGAACATTGTTGTCATGATGTATGATGATATTGCCTACAGTGCAGAAAACCCTACTCCTGGAACTATTATTAATCAGCCAAATGGACCTAATGTATACAAAGGTGTTGTGAAGGACTATATTAAAGAGGATGTCACCCCTGAGAATTTCTTAAATGTGTTAAAAGGAAACAAAGAAGCCATGAAAGGTATTGGCAGTGGCAAAGTAATTGACAGTGGACCAGATGACAATGTGTTTGTGTATTTTGCTGATCATGGTGCTCCAAACATCATTGCTTTTCCCACTAGTGAACTCCATGCAAAAGATTTGAATGACGCTATCATGTACATGAGTAACAACAAGAAATACAAACAGATGGTGTTTTATATTGAAGCTTGTGAGTCTGGCTCCATGTTCATGAACCACAAGTTGCGCTCAGACATCAATGTGTTTGCGACTACCGCAGCCAATGGCGCTGAGTCATCGTACGCTTGTTACTATGATAGCAGACGACAAACGTTTCTGGGAGATGTCTATAGCGTAAAATGGCTAGAAAACTCTGACCAGGCCAACCTCAACACTGAAACCCTCACTCAACAGTTTAAAACGGTGAAAGCCGAAACAAACGAAAGTCATGTTACGGAATACGGAGACTTGACCATGGGAAGTTTGGTGTTGGGGCTGTTCCAAGGCGAAAGCACTTCGCTTGAAGAAGTTACTGAAAGTGTTCCTATTACCGATGTTGTTCCTTCCCCGGATGTTCCCGTAGAGATTTTCCTTCACCGAATGGAAGATGCCAAGACGAAAGAAGAACACGATGATGCAGAGAAGAAGTTAAGAGATGAACTCAACAGGCGGAGGTCGGTGGTTGAGGTGGTGCGAGGAATTGTGCATAAACTGGCGACCGCAGAGGAAGCGGAGGAGGTGTTGAACAAACCTGCAATGCCTTACCACGAGGAATGTTACAAACATTCAGTCTCTCATTTCCGCAAACATTGTTTTGACTTTAACAGGTACGAACATGCGCTGAGACATGTCTATGTCCTTGCTAACCTCTGTGATAAAGGTTTCCATACCCAACGAATCTTGGACGTTATTGAGCAGAGCTGTCCTGTTGCTTTTTAATTCTTCGCCCTCTTCAGAGATTTCTtacttagttttttttttatatgattCTTCagttcttttaaatatttgtacaTATTTTAATCAGTTTTTTAACGGAACGCTTTGCAAGTCGCAATTGTTAATTTGTTATGTGTTCTTTGTAACATTAATCATTTTTGAGAAGTTTTTTCCAGGAACTAGTTTGTTTTATCACTGGGGAATACTGTCAAAACTCTCATTGATAAAGATAAGATTGATATAAGAAACGAATTTTTAATGACCTCAAAGGAATAATCCACAGAATCACCATGAGCACGGTACGCTTGctatgtttgaaaatattcagGAATAAATCCGATGAcggaaaatttcaaatttgtcTGAAATTCATAAGATTCATTCTATTTCTCAATTGGTTATAACTCTTTTTCTATacatttttatggtttttgaCTATAGAAAAGGTTGTTCCCCATAACAAATGCTAAAAAATAGTGTACAGTATGTCCTATtatgaaaaacttaaaattttcatatttaaggGATTGTGACGTCATTGAGCAGAGCTGTCCTGTTGCTTTTTAATTCTTCGCCCTCTTCAGAGATTTCTTacttagtttttttttatatgattCTTCagttcttttaaatatttgtacaTATTTTAATCAGTTTTTTAACGGAACGCTTTGCAAGTCGCAATTGTTAATTTGTTATGTGTTCTTTGTAACATTAATCATTTTTGAGAAGTGGGGATATTTTGTTGCGTCATCTACACAGTATATCTGAGAAAATCGATGCTATTGTGATTGAATACACTTCTCCAAACATATTTGTAAGAAATGGCACTCTAATAAGACCGAAGGAAGGTTGTAATAAGTGAGACTTTGGATAAAGGGTTTGCTTTTGTACACACGCGTGTTTGATATTAGCTAGCTGCTGGTAAATTGAGTTAATTAAACTATAATTaacgataaaagacggttctcgacgataagaccaatcaaacagTCTTCT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q4R4T8	Legumain OS=Macaca fascicularis OX=9541 GN=LGMN PE=2 SV=1
Q99538	Legumain OS=Homo sapiens OX=9606 GN=LGMN PE=1 SV=1
Q5R5D9	Legumain OS=Pongo abelii OX=9601 GN=LGMN PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003724 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01650 all species →	Peptidase_C13	Peptidase C13 family	Family	Interproscan
PF20985 all species →	Legum_prodom	Legumain, prodomain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR043577 all species →	Family	Asparaginyl endopeptidase	Interproscan
IPR046427 all species →	Homologous_superfamily	Legumain prodomain superfamily	Interproscan
IPR001096 all species →	Family	Peptidase C13, legumain	Interproscan
IPR048501 all species →	Domain	Legumain, prodomain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12000 all species →	HEMOGLOBINASE FAMILY MEMBER	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004197 all species →	Molecular Function	cysteine-type endopeptidase activity	Interproscan
GO:0051603 all species →	Biological Process	proteolysis involved in protein catabolic process	Interproscan
GO:0006508 all species →	Biological Process	proteolysis	Interproscan
GO:0008233 all species →	Molecular Function	peptidase activity	Interproscan
GO:0006624 all species →	Biological Process	vacuolar protein processing	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01369	LGMN; legumain	EC:3.4.22.34	Peptidases and inhibitors	ko01002	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Candelabrum cocksii tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Candelabrum cocksii, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →