Genomic Location: :...
NR annotation: XP_047123873.1, E3 ubiquitin-protein ligase HERC2 isoform X1 [Hydra vulgaris]
| CDS | |||||
| ENSQNNT00000022273 | |||||
| Transcript |
| ENSQNNT00000022273 |
| Protein |
| ENSQNNP00000021503.1 |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q4U2R1 | E3 ubiquitin-protein ligase HERC2 OS=Mus musculus OX=10090 GN=Herc2 PE=1 SV=3 | ||||
| O95714 | E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN=HERC2 PE=1 SV=2 | ||||
| Q9VR91 | Probable E3 ubiquitin-protein ligase HERC2 OS=Drosophila melanogaster OX=7227 GN=HERC2 PE=1 SV=3 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | E3|E3 activity|HECT |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00632 | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF00415 | RCC1 | Regulator of chromosome condensation (RCC1) repeat | Repeat | Interproscan |
| PF06701 | MIB_HERC2 | Mib_herc2 | Domain | Interproscan |
| PF13540 | RCC1_2 | Regulator of chromosome condensation (RCC1) repeat | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000408 | Repeat | Regulator of chromosome condensation, RCC1 | Interproscan |
| IPR009091 | Homologous_superfamily | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II | Interproscan |
| IPR035983 | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| IPR000569 | Domain | HECT domain | Interproscan |
| IPR037252 | Homologous_superfamily | Mib/herc2 domain superfamily | Interproscan |
| IPR010606 | Domain | Mib-herc2 | Interproscan |
| IPR051210 | Family | Ubiquitin ligases and GEF domain-containing protein | Interproscan |
| IPR015940 | Domain | Ubiquitin-associated domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22870 | REGULATOR OF CHROMOSOME CONDENSATION | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004842 | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0016567 | Biological Process | protein ubiquitination | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K10595 | HERC2; E3 ubiquitin-protein ligase HERC2 | EC:2.3.2.26 | DNA repair and recombination proteins | ko03400 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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